Publications by authors named "Ying-wei Xie"
LIMD2 was found upregulated in various tumors and metastatic samples and associated with a poor prognosis. But the role of LIMD2 in clear cell renal cell carcinoma (ccRCC) remains elusive. The expression of LIMD2 in ccRCC was analyzed using cohort data downloaded from TCGA and ICGC databases.
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- - Lung cancer, particularly non-small cell lung carcinoma (Non-SCLC), is the leading cause of cancer-related deaths globally, with adenocarcinomas making up a significant portion.
- - Researchers used proteomics to compare protein profiles of lung adenocarcinoma tissue to normal tissue, identifying 32 differentially expressed proteins; notably, PKM2 and cofilin-1 were found to be upregulated in adenocarcinoma.
- - Further analysis revealed that targeting PKM2 and cofilin-1 could inhibit tumor growth and metastasis, suggesting they may be valuable for diagnostics, prognosis, and potential therapies for pulmonary adenocarcinoma.