[Changes of plasma fibrinolysis system and the effect of captopril in high altitude pulmonary edema].

Objective: To investigate the changes of plasma fibrinolysis system and the effect of captopril in patients with high altitude pulmonary edema.

Methods: The plasma levels of tissue plasminogen activator (tPA) and plasminogen activator inhibitor-1 (PAI-1) were measured before and after treatment in the captopril-group (group A, 35 cases) and the routine-group (group B, 37 cases) of patients with HAPE, while 20 healthy volunteers served as the control (group C).

Results: The plasma level of tPA was (0.