Publications by authors named "Ying-chan Wang"

We aimed to determine the relationship between electrophysiological signatures of error monitoring and clinical insight among outpatients with attenuated psychosis syndrome (APS) and first-episode psychosis (FEP). Error-related negativity (ERN), error positivity (Pe), and correct response negativity (CRN) were recorded during a modified flanker task for patients with FEP (n = 32), APS individuals (n = 58), and healthy controls (HC, n = 49). Clinical insight was measured using the Schedule of Assessment of Insight (SAI) and included awareness of illness (SAI-illness), relabeling of specific symptoms (SAI-symptoms), and treatment compliance (SAI-treatment).

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Error monitoring plays a key role in people's adjustment to social life. This study aimed to examine the direct (DE) and indirect effects (IDE) of error monitoring, as indicated by error-related negativity (ERN), on social functioning in a clinical cohort from high-risk (APS) to first-episode psychosis (FEP). This study recruited 100 outpatients and 49 healthy controls (HC).

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Poor cognitive insight, including low self-reflectiveness and high self-certainty, contributes to poor clinical insight, which includes awareness of illness, relabelling of specific symptoms, and treatment compliance. However, inconsistent results regarding cognitive insight among individuals at clinical high risk of psychosis (CHR) have been reported. This study investigated the difference in cognitive insight among groups with different severity of positive symptoms and analysed the effect of cognitive insight on clinical insight in each group.

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This study examines whether cognitive insight is impaired in high-risk individuals with attenuated psychotic symptoms (APS) and explores the relationship between cognitive and clinical insight at different durations of untreated attenuated psychotic symptoms (DUAPS). The Structured Interview for Psychosis high-risk Syndrome (SIPS) was used to identify APS individuals. APS ( = 121) and healthy control (HC, = 87) subjects were asked to complete the Beck Cognitive Insight Scale (BCIS).

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Article Synopsis
  • - The study investigates the various subclones present in acute myeloid leukemia (AML) characterized by the genetic abnormality t(8;21), using a detailed method called quantitative multicolor-fluorescence in situ hybridization (QM-FISH) to track genetic variations and evolutionary relationships among them.
  • - Researchers examined 36 AML cases along with one relapsed case, identifying multiple genetic alterations including additional signals for genes such as AML1, ETO, and WT1, revealing crucial information about how these subclones differ and evolve over time.
  • - Results showed that a significant portion of the cases displayed genetic abnormalities, particularly indicating that male patients often experienced deletion of the AML1 signal, suggesting a potential link between these
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