Publications by authors named "Ying-Zhi Qin"

Background: Acupuncture, a traditional Chinese medical treatment, has been gaining popularity over the years. However, it also presents certain risks. We report a case of a patient who discovered a foreign body in their lung several years after undergoing acupuncture.

View Article and Find Full Text PDF

Background: Our current study was performed with an attempt to detect the expression of microRNA-22-3p (miR-22-3p) in lung adenocarcinoma, as well as to analyze its role in clinical practice. In addition, its relationship with vascular endothelial growth factor (VEGF) and metastasis related indexes was focused.

Material And Method: The trials in which 62 cases of lung adenocarcinoma were received to collect tumor tissue (study group) and normal lung tissue (control group) were eligible for this study.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigated how silencing the TUSC3 gene affects the growth and sensitivity to radiation in human lung cancer (A549) cells under low oxygen (hypoxic) conditions.
  • It established a hypoxic model using varying concentrations of CoCl and observed that increased TUSC3 levels hinder cell growth while promoting apoptosis (cell death).
  • The findings showed that silencing TUSC3 not only inhibited cell proliferation but also increased the sensitivity to radiation treatment and enhanced autophagy in these hypoxic cancer cells.
View Article and Find Full Text PDF
Article Synopsis
  • Thymic neuroendocrine carcinomas (TNECs) are rare tumors that can cause ectopic ACTH syndrome (EAS), which leads to Cushing's syndrome; however, there's a lack of comprehensive treatment guidelines in existing literature.
  • This study analyzed the surgical outcomes of 16 patients (ages 13-47) with EAS from TNECs at a medical institution over 30 years, showing that early diagnosis and surgical intervention significantly improve overall and progression-free survival rates.
  • The research emphasizes the importance of contrast-enhanced thoracic CT scans for diagnosis and highlights that complete surgical resection is the most effective treatment for these aggressive tumors.
View Article and Find Full Text PDF

Background: Altered miR-148/152 family expression contributes to human carcinogenesis. This study was designed to detect the potential for using miR-148/152 family as biomarkers for NSCLC patients.

Material/methods: The relative expression levels of miR-148/152 family (miR-148a, miR-148b, and miR-152) in serum of 36 non-small-cell lung carcinoma (NSCLC) patients, 20 patients with benign pulmonary diseases (BPD), and 10 healthy individuals were assessed by real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR).

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed 48 patients with intrathoracic Castleman disease (CD) over a 20-year period, distinguishing between unicentric CD (UCD) and multicentric CD (MCD).
  • UCD patients were younger and presented fewer symptoms compared to the older and more symptomatic MCD patients, who often showed severe illness indicators such as fever and organ enlargement.
  • The research found that UCD predominantly displayed solitary masses, while MCD had more complex CT findings and required a variety of biopsy methods, with many MCD patients undergoing chemotherapy and experiencing variable outcomes.
View Article and Find Full Text PDF
Article Synopsis
  • * Out of 208 patients, 168 were successfully weaned (around 80%), with different average RSBI values observed between the PSV and T-piece groups at the 30-minute mark (67.18 vs. 99.11 breaths/min/L).
  • * Threshold values of 75 breaths/min/L for PSV and 100 breaths/min/L for T-piece were found to have the highest diagnostic accuracy for predicting successful weaning, reinforcing that RSBI changes can also indicate weaning success.
View Article and Find Full Text PDF

Objective: To analyze the clinical features, diagnosis and treatment of lung cancer associated paraneoplastic limbic encephalitis (PLE).

Methods: The clinical data of 7 cases of patients with lung cancer associated PLE out of 8927 patients of lung cancer from January 2000 to May 2010 was analyzed retrospectively. All the patients were male, aging from 41 to 54 years with a mean of 48 years.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to evaluate how well a respiratory multiple index (CROP), which includes factors like compliance, respiratory rate, and oxygenation, predicts the success of weaning patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) from mechanical ventilation.
  • - Conducted over two years, the prospective study involved 215 AECOPD patients in the ICU, all of whom had severe respiratory issues and underwent a spontaneous breathing trial before extubation; their respiratory metrics were recorded to calculate the CROP value.
  • - Out of 215 patients, 182 successfully weaned from ventilation, while 33 did not; results showed no significant demographic or health score differences between the two groups, indicating C
View Article and Find Full Text PDF

Objective: To evaluate the use of titanium mesh reconstruction after sternal tumor resection.

Methods: From January 2007 to January 2011, 14 patients with sternal tumors were admitted into Peking Union Medical Hospital. The clinical characteristics, surgical resection, and technique of reconstruction were reviewed.

View Article and Find Full Text PDF

Objective: To evaluate the clinical features, diagnosis, treatment, and outcome of intralobar pulmonary sequestration (ILS).

Methods: Patients who were diagnosed with ILS in our hospital between January 1988 and January 2009 were retrospectively reviewed. We recorded the clinical symptoms, imaging findings, operative technique, complications, and outcome of these patients.

View Article and Find Full Text PDF

Objective: To summarize the clinical method and initial experience of extracorporeal membrane oxygenation (ECMO) supportive treatment in influenza A H1N1 serious patients.

Methods: In 5 critically ill patients with influenza A H1N1, their arterial oxygen saturation was 0.70 to 0.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to investigate the effectiveness of extracorporeal membrane oxygenation (ECMO) for patients with severe pneumonia caused by influenza A H1N1, focusing on protecting lung function.
  • Five patients were treated with ECMO alongside various mechanical ventilation methods, resulting in two patient deaths and three recoveries, with different ventilation strategies employed.
  • The findings suggest that ECMO can significantly improve outcomes for patients with severe pneumonia by reducing lung damage when using a lung protection strategy, emphasizing the importance of lung rest during treatment.
View Article and Find Full Text PDF
Article Synopsis
  • * Methods: Five sheep, under anesthesia and on mechanical ventilation, were monitored using different tidal volume levels (6, 10, 15, 20 ml/kg) in bi-level positive airway pressure (BiPAP) mode versus synchronized intermittent mandatory ventilation (SIMV) mode.
  • * Results: Increasing tidal volumes resulted in decreased cardiac index and intrathoracic blood volume index, with significant differences noted at 15 ml/kg and 20 ml/kg compared to 6 ml/kg, along with changes in systemic vascular resistance index and mean
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to compare the effects of different mechanical ventilation modes (BIPAP vs SIMV) on cardiac index (CI) and intrathoracic blood volume index (ITBVI) in patients with normal versus dysfunctional hearts.
  • Twenty-four patients were monitored, revealing that in patients with normal heart function, there were no significant differences in arterial pressure, CI, and ITBVI between the two ventilation modes, although systemic vascular resistance was higher in the BIPAP mode.
  • In patients with heart dysfunction, both CI and ITBVI decreased in SIMV mode, significantly so in the 10 ml/kg group, while BIPAP consistently demonstrated higher mean airway pressure across all tidal volume levels.
View Article and Find Full Text PDF
Article Synopsis
  • This study aims to assess the effectiveness of preemptive anti-Candida treatment in critically ill patients at high risk for invasive Candida infections, using a corrected colonization index (CCI) to guide treatment decisions.* -
  • Conducted in five hospitals, 110 patients were divided into two groups—one receiving treatment based on clinical judgment and the other guided by CCI readings—with no substantial differences in patient demographics or outcomes between the groups.* -
  • Results indicate that while the CCI group initiated anti-Candida treatment significantly earlier during sepsis onset, they experienced longer ICU stays and increased complications related to enteral nutrition compared to the control group.*
View Article and Find Full Text PDF

Objective: To determine the threshold value of rapid-shallow-breathing index (RSBI) and its increased percentage (Delta RSBI) as predictors for successful weaning in spontaneous breathing trial (SBT) with pressure support ventilation (PSV) and T-piece.

Methods: In 2007, there were 208 patients on ventilators with oral intubation. They were divided into two groups: the PSV group (93 patients) and the T-piece group (115 patients).

View Article and Find Full Text PDF

Objective: To study the value of cough peak expiratory flow (CPEF) in predicting extubation outcome of patients.

Methods: A prospective study of 200 adult patients was conducted and treated in the Third Central Hospital intensive care unit (ICU), receiving mechanical ventilation (MV) via an endotracheal tube during November 2006 through December 2007. All the patients received MV longer than 24 hours.

View Article and Find Full Text PDF