Publications by authors named "Ying-Zhen Yu"
Int J Mol Sci
February 2021
Article Synopsis
- Regulation of actin dynamics is crucial for cell movement, particularly in cancer, where cells invade and spread; ABRACL plays a significant role in this process.
- High levels of ABRACL are linked to increased migration and tumor growth in cancer cells, with evidence showing that ABRACL localizes with actin at the leading edge of migrating cells.
- The study indicates that ABRACL interacts with cofilin, enhancing actin polymerization, and its high expression in colorectal cancer correlates with metastatic spread, suggesting its importance in cancer progression.
