Publications by authors named "Ying-Yu Jiang"
Although essential for cardiovascular therapy, the pleiotropic effects of statins on ischemic stroke lack clinical evidence. This study examined the effects of statins beyond low-density lipoprotein cholesterol (LDL-C) levels on mortality and stroke severity. A total of 825,874 patients with ischemic stroke were included in this study, of whom 125,650 statin users were 1:1 matched with non-users based on their LDL-C levels (±0.
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- Efforts to enhance stroke care in rural China have revealed a significant lack of comprehensive data comparing care and outcomes between rural and urban hospitals.
- A study analyzing 1,583,271 patients from 1930 hospitals found that rural hospitals provided less effective management for acute ischemic stroke, evidenced by lower rates of critical treatments compared to urban hospitals.
- Despite these disparities in treatment quality, the overall differences in in-hospital outcomes between rural and urban patients were minimal, with rural patients showing slightly higher in-hospital death or discharge against medical advice but lower rates of complications.
Aim: The aim of the study was to analyze the association between inflammatory marker profiles and in-hospital neurological deterioration (ND) in acute ischemic stroke (AIS) patients.
Methods: Data from patients with minor AIS from the Third China National Stroke Registry were analyzed. Inflammatory cytokine levels within 24 h of admission were measured.
The modified Rankin Scale change score (ΔmRS) is useful for evaluating acute poststroke functional improvement or deterioration. We investigated the relationship between multiple biomarkers and ΔmRS by analyzing data on 6931 patients with acute ischemic stroke (average age 62.3 ± 11.
View Article and Find Full Text PDFDuring the acute stage of ischemic stroke, it remains unclear how to interpret the low low-density lipoprotein cholesterol (LDL-C) level. We aimed to evaluate the association between LDL-C levels, post-stroke infection, and all-cause mortality. 804,855 ischemic stroke patients were included.
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- The study aimed to compare the likelihood of young adults (<50 years) receiving intravenous tissue plasminogen activator (IV tPA) for acute ischemic stroke (AIS) versus older adults (≥50 years) and assess treatment times.
- Data from the Chinese Stroke Center Alliance registry showed that a higher percentage of young adults received IV tPA compared to older adults, but both groups had similar treatment times.
- Young adults demonstrated better in-hospital outcomes, showing lower in-hospital mortality and higher chances of independent ambulation at discharge than older adults, likely influenced by differences in stroke severity.