Publications by authors named "Ying-Yu Hu"
Dinoflagellate genomes have a unique architecture that may constrain their physiological and biochemical responsiveness to environmental stressors. Here we quantified how nitrogen (N) starvation influenced macromolecular allocation and C:N:P of three photosynthetic marine dinoflagellates, representing different taxonomic classes and genome sizes. Dinoflagellates respond to nitrogen starvation by decreasing cellular nitrogen, protein and RNA content, but unlike many other eukaryotic phytoplankton examined RNA:protein is invariant.
View Article and Find Full Text PDFBackground: Previous studies have indicated that nitric oxide synthase 2 () genetic variations are involved in delayed fracture healing and fracture non-union. Whether these genetic variants associate with the development of osteomyelitis (OM) remains unclear. Here, we analyzed the potential relationships between genetic variations and the risk of developing post-traumatic OM (PTOM) in a Chinese Han population.
View Article and Find Full Text PDFArticle Synopsis
- The study identified high levels of MCF2L in hepatocellular carcinoma (HCC) tissues, suggesting it plays a role in resistance to sorafenib, a common cancer treatment.
- Various experiments confirmed that reducing MCF2L levels increased cell death when treated with sorafenib, and that this process is linked to ferroptosis, a specific type of cell death.
- The research also indicated that MCF2L influences the PI3K/AKT signaling pathway via a RhoA/Rac1-dependent mechanism, making it a potential target for overcoming treatment resistance in HCC.
Objective: To help selecting appropriate meridians and acupoints in clinical practice and experimental study for Parkinson's disease (PD), the rules of meridians and acupoints selection of acupuncture and moxibustion were analyzed in domestic and foreign clinical treatment for PD based on data mining techniques.
Methods: Literature about PD treated by acupuncture and moxibustion in China and abroad was searched and selected from China National Knowledge Infrastructure and MEDLINE. Then the data from all eligible articles were extracted to establish the database of acupuncture-moxibustion for PD.