Publications by authors named "Ying-Yi Shen"
Article Synopsis
- The study aims to understand how alveolar bone changes after maxillary incisor extraction in East Asian individuals, which is crucial for planning dental implants.
- Researchers used cone-beam computerized tomography (CBCT) to analyze the bone measurements in 125 patients three months after extraction, finding significant resorption in both width and height.
- Results showed a notable horizontal resorption pattern, creating an "inverted triangle" shape in the remaining bone, indicating that the changes are consistent across genders and tooth positions but vary by distance from the ridge crest.
Objective: To investigate the effects of cyclic stretch-induced periodontal ligament cell (PDLC) exosomes on osteoblast differentiation, and to explore their regulatory role in mechanical force-related periodontal tissue remodeling.
Design: After applying 20 % cyclic stretch loading to PDLCs, exosomes were extracted from the supernatant and co-cultured with osteoblasts to detect their effects on osteogenic differentiation. Meanwhile, the exosomes were sequenced by high-throughput microRNA sequencing for bioinformatic analysis and validation to explore exosome signaling pathways through miRNAs.