Publications by authors named "Ying-Xin Ouyang"
Int J Mol Sci
August 2022
Article Synopsis
- Citrullination of proteins is important for protein function and immune responses, specifically in the context of autoimmune arthritis.
- In a study using HLA-DR1 transgenic mice, citrullinated collagen did not reduce arthritis severity, unlike native collagen which showed protective effects.
- The research indicates that citrullinated collagen may block the signaling pathway of a key inhibitory receptor (LAIR-1), suggesting a potential target for treating autoimmune arthritis by manipulating T-cell responses.
