The antifungal activity of plant essential oils (EOs) extracted by steam distillation from seven different species (Cinnamon, Anise, Clove, Citronella, Peppermint, Pepper, and Camphor) was investigated. Three common fungi were isolated from moldy wheat bread, which were identified as Aspergillus niger, A. oryzae, and A.
View Article and Find Full Text PDFMethyl protodioscin (MPD) is a steroid saponin which has been well known for its pharmacological properties. Herein, we evaluated the anti-cancer activity of MPD for proliferation inhibition and apoptosis induction in Hela cells. MPD was purified from the rhizoma of Polygonatum sibiricum primarily and identified by HPLC, UPLC-TOF-MS/MS and NMR analysis, respectively.
View Article and Find Full Text PDFThe molecular mechanism of Juglone-induced cell cycle arrest and apoptosis in human endometrial cancer cells was investigated. Juglone was purified from the green husk of Carya cathayensis Sarg and identified by HPLC, LC-MS/MS, and NMR. At an IC of 20.
View Article and Find Full Text PDFWe investigated the anti-cancer activity of Licochalcone A (LCA), extracted from licorice root. LCA inhibited the proliferation of HepG cells with IC (65.96 μM) for 24 h and IC (44.
View Article and Find Full Text PDFDioscin has been known for its anti-cancer activity; however, its detailed molecular mechanisms have not been studied so far. Herein, we evaluated the anti-cancer activity of dioscin for proliferation inhibition and apoptosis in HepG2 cancer cells. Initially, dioscin was purified and identified from Polygonatum sibiricum by HPLC, MS, and NMR analysis, respectively.
View Article and Find Full Text PDFThe peony seed dreg polysaccharide (PSDPs) fractions and their modified derivatives were examined for their antibacterial potential. PSDPs along with their derivatives exhibited appreciable antibacterial activity against both Gram-positive (B. subtilis and S.
View Article and Find Full Text PDFFour types of sequentially extracted peony seed dreg polysaccharides (PSDPs) fractions were modified through sulfation, phosphorylation and carboxymethylation and studied for their in vitro antioxidant characteristics. The modified derivatives showed decreased sugar and protein content, while uronic acid content was elevated as compared to native (un-modified) polysaccharides. Further, modified derivatives shared the similar maximum absorption peaks indicating their homogeneous nature.
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