Publications by authors named "Ying-Shun Zhou"
Article Synopsis
- * A study identified a specific strain, SWU01, which had a 162,552-bp plasmid (pSWU01) containing important resistance (bla) and virulence (iroN) genes.
- * The plasmid's genetic makeup includes multiple resistance genes and virulence factors, posing new challenges for treatment of infections caused by this hypermucoviscous K. pneumoniae strain.
Article Synopsis
- - The study investigated the prevalence of virulence genes in Klebsiella pneumoniae strains that produce beta-lactamase (bla) and form high biofilms, analyzing 43 unique isolates collected over two years out of 429 tested.
- - The results showed that the strains exhibited varying degrees of antibiotic resistance (MIC for carbapenems ranged from 4 to 32 μg/ml) and were primarily classified into K2 and ST11 genotypes, with 23 out of 43 strains being ST11.
- - All isolates possessed key virulence factors, indicating a high frequency of potentially harmful traits in these biofilm-producing strains, underscoring the need for greater clinical awareness of infections caused by Klebsi
One genome and 12 Nsp2 genes of porcine reproductive and respiratory syndrome virus (PRRSV), isolated from southwestern China during 2009-2010, were sequenced and analyzed. The whole genome comparison analysis revealed that SCwhn09CD is a North American-type PRRSV with separate 30aa deletion in Nsp2 gene, and its sequence highly identical to highly pathogenic PRRSV (HP-PRRSV) outbreak in 2006 in almost half area of China. However, an extra 7aa deletion was detected in its Nsp2 coding region.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the avian infectious bronchitis virus (IBV) and the effectiveness of a multi-epitope peptide called EpiC in generating immune responses.
- Researchers introduced the EpiC gene into Lactococcus lactis NZ3900 to create recombinant strains that can express the peptide in different forms.
- Oral vaccination of chickens with these recombinant strains led to stronger immune responses and protection against a lethal IBV strain, suggesting L. lactis could be a viable option for oral vaccines against IBV infection.
Infectious bronchitis virus (IBV) strain H120 was successfully rescued as infectious clone by reverse genetics. Thirteen 1.5-2.
View Article and Find Full Text PDFBackground: Foot-and-mouth disease virus (FMDV) serotype Asia1 generally infects cattle and sheep, while its infection of pigs is rarely reported. In 2005-2007, FMD outbreaks caused by Asia1 type occurred in many regions of China, as well as some parts of East Asia countries. During the outbreaks, there was not any report that pigs were found to be clinically infected.
View Article and Find Full Text PDFThis study aims to describe the erythromycin resistance phenotypes and genotypes, and the prevalence of virulence genes of Enterococcus faecalis isolated from swine in China. A total of 117 nonreplicate E. faecalis isolates, obtained from 502 clinical samples taken from different pig farms between 2007 and 2009 were included in the study.
View Article and Find Full Text PDFLittle is known about the antimicrobial resistance mechanisms in Klebsiella pneumoniae from swine in China. Thus, this paper aims to demonstrate the β-lactam resistance phenotypes and genotypes of K. pneumoniae isolates from swine in southwestern China, detect possible new β-lactamase variants, and determine whether or not the variants differ in their antibiotic resistance.
View Article and Find Full Text PDF