Publications by authors named "Ying-Qia Hong"
Metabolomic research has revealed that metabolites play an important role in prostate cancer development and progression. Previous studies have suggested that prostate cancer cell proliferation is induced by advanced glycation end products (AGEs) exposure, but the mechanism of this induction remains unknown. This study investigated the molecular mechanisms underlying the proliferative response of prostate cancer cell to the interaction of AGEs and the receptor for advanced glycation end products (RAGE).
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- A meta-analysis was conducted to examine the relationship between FOXO3A gene polymorphisms and human longevity, involving seven studies with over 10,000 participants from various ethnic backgrounds.
- Five specific polymorphisms (rs2802292, rs2764264, rs13217795, rs1935949, and rs2802288) were found to be associated with increased longevity, with rs2802292 and rs2764264 showing significant effects specifically in males.
- The study concluded that while there are notable associations between these FOXO3A polymorphisms and longevity, more research is needed to validate the findings and explore their mechanisms.
[A meta-analysis of holmium laser enucleation of the prostate for benign prostatic hyperplasia].
Zhonghua Nan Ke Xue
December 2011
Objective: To evaluate the effectiveness and safety of holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostate (TURP)/open prostatectomy (OP) in the treatment of bladder outlet obstruction (BOO) secondary to benign prostatic hyperplasia (BPH).
Methods: We searched Medline, Cochrane Library, Embase, Wanfang and CBM for randomized controlled trials (RCT) comparing HoLEP with TURP/OP. Comparable data were extracted from eligible studies and pooled for meta-analysis using RevMan5.