Publications by authors named "Ying-Ping Xiao"

Article Synopsis
  • The study investigates the common genetic factors between pediatric acute lymphoblastic leukemia (ALL) and pediatric sepsis, aiming to identify shared key genes.
  • Researchers analyzed data from the Gene Expression Omnibus (GEO) database, focusing on differentially expressed genes (DEGs) in two specific datasets (GSE13904 and GSE79533).
  • They discovered three key genes (HCK, NOG, RNF125) that show potential diagnostic value for both conditions, concluding that these genes may have varying effects on immune responses in ALL and sepsis.
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Host defense peptides (HDPs) represent a large group of diverse small peptides that play important roles in host defense and disease resistance. In vertebrates, one of the main types of HDPs belong to defensins, which are less than 100 amino acid residues and characterized by a highly conserved motif of cysteine residues. Recently, a subfamily of defensins, namely ovodefensins (OvoDs), has been identified in birds and reptiles.

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A novel metabolomic method based on gas chromatography/mass spectrometry (GC-MS) was applied to determine the metabolites in the serum of piglets in response to weaning and dietary L-glutamine (Gln) supplementation. Thirty-six 21-d-old piglets were randomly assigned into three groups. One group continued to suckle from the sows (suckling group), whereas the other two groups were weaned and their diets were supplemented with 1% (w/w) Gln or isonitrogenous L-alanine, respectively, representing Gln group or control group.

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