Publications by authors named "Ying-Lu Ge"
Characterization of Altered Oropharyngeal Microbiota in Hospitalized Patients With Mild SARS-CoV-2 Infection.
Front Cell Infect Microbiol
April 2022
Article Synopsis
- COVID-19 is a significant global health issue, and this study explores the relationship between oropharyngeal microbiota and the severity of the infection in mild COVID-19 patients compared to healthy individuals.
- Researchers used full-length 16S rRNA gene sequencing to analyze the microbiota of 10 mild COVID-19 patients and 10 healthy controls, finding distinct differences in microbial composition, including increased opportunistic pathogens and decreased beneficial species in COVID-19 patients.
- The study suggests that changes in oropharyngeal microbiota might influence COVID-19 severity, as certain bacteria correlate with viral load and clinical indicators; however, the small sample size means these findings should be interpreted cautiously.
Changes in Serum Neutralizing Antibodies Levels During Convalescence of COVID-19 Patients.
Front Med (Lausanne)
February 2022
Article Synopsis
- Detection of SARS-CoV-2 antibodies in serum is being used to identify COVID-19 cases and track immune response over time.
- A study analyzed 148 serum samples from 37 COVID-19 patients and found that neutralizing antibodies and IgG can persist at low levels for 190-266 days post-infection.
- These findings enhance understanding of antibody duration in COVID-19 patients and can inform evaluations of immune responses following vaccination.
H9N2 viruses can cause great economic losses to the domestic poultry industry when co-infected with other influenza viruses or pathogens. . To better understand the molecular characteristics of H9N2 avian influenza viruses (AIVs) and analyze the genetic evolutionary relationship, we isolated three H9N2 subtypes AIVs from nasopharyngeal swab specimens from the three cases reported in Anhui province since 2015, and systematically reviewed the genome-wide data of 21 poultry--isolated H9N2 viruses during 1998-2017.
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