Publications by authors named "Ying-Guo Tian"
Bioengineered
December 2021
Article Synopsis
- MiR-130a-3p shows anti-tumor effects across various cancers and may specifically inhibit the Wnt signaling pathway, which is crucial in tumor development.
- Both colorectal cancer (CRC) tissues and cell lines exhibited lower levels of miR-130a-3p compared to normal controls, indicating its potential role in CRC progression.
- Overexpression of miR-130a-3p reduced CRC cell growth and downregulated WNT1 and its downstream factors, with WNT1 acting as a direct target of miR-130a-3p; thus, both could be promising targets for CRC treatment.
