Publications by authors named "Ying-Cong Ren"
Hyperoxia-induced acute lung injury (HALI) is a complication of oxygen therapy. Ferroptosis is a vital factor in HALI. This paper was anticipated to investigate the underlying mechanism of wedelolactone (WED) on ferroptosis in HALI.
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- Sepsis-induced myocardial injury is a serious complication in ICU patients, and the protective role of a short peptide called Annexin A1 (ANXA1sp) against this condition is being investigated.
- ANXA1sp improves survival and cardiac function in sepsis models by reducing inflammatory markers and enhancing mitochondrial health through the upregulation of a protein called SIRT3.
- The study shows that ANXA1sp helps mitigate sepsis-induced myocardial injury by promoting mitochondrial biosynthesis and limiting oxidative stress, highlighting the importance of SIRT3 in this protective mechanism.
Inhibition of type II alveolar epithelial (AE-II) cell apoptosis is a critical way to cure hyperoxia-induced acute lung injury (HALI). It has been reported that miR-21-5p could reduce HO-induced apoptosis in AE-II cells. However, the upstream molecular mechanism remains unclear.
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