Cerebral Arteriovenous Malformation in Wyburn-Mason Syndrome.

The cases of Wyburn-Mason syndrome reported in recent years have been professional and significant. However, most of the reports focus on retinal lesions and few demonstrate the disorder of the brain; thus, to the best of the authors' knowledge, there is no effective method to cure the retinal lesions at this time. Racemose hemangioma in the ocular fundus is easy for an ophthalmologist to detect, and once this is identified, the ophthalmologist should closely monitor the patient's brain.

Time-dependent expression of PEDF and VEGF in blood serum and retina of rats with oxygen-induced retinopathy.

The effects of the balance changes of pigment epithelium growth factor (PEDF) and vascular endothelial growth factor (VEGF) in whole-body and retinal tissue on rats with oxygen-induced retinopathy were investigated. Forty-eight neonatal SD rats at the age of 7 days were randomly divided into 4 groups. The neonatal rats in experimental groups were exposed to 75% to 80% oxygen for 5 days and then to normal air, and those in control groups were kept feeding in normal air.

Changed trends of major causes of visual impairment in Sichuan, China from 1987 to 2006.

Aim: To study the trends of major causes of visual impairment (VI) in adults in Sichuan, China and evaluate the effect of aging on the trends.

Methods: We used data from the National Sample Survey on Disabilities (NSSD) in Sichuan province conducted in 1987 and 2006. The age-adjusted prevalence of major causes of VI and the prevalence stratified by age in each cause were calculated and compared.

[Rapid assessment of avoidable blindness cataract in country Anyue in Sichuan Province].

Objective: To explore the prevalence of cataract and measure the outcomes after cataract surgery in patients aged ≥ 50 years and to evaluate the validity of Rapid Assessment of Avoidable Blindness (RAAB).

Methods: A total of 76 clusters of 50 patients aged ≥ 50 years were selected through probability proportionate to size sampling. The measurements of visual acuity (VA) were made with a tumbling-E chart and the diagnosis of the principal cause of visual impairment by an ophthalmologist.

Comparison on conjunctival sac bacterial flora of the seniors with dry eye in Ganzi autonomous prefecture.

Aim: To compare the bacterial flora in palpebral conjunctiva of xerophthalmia seniors of Tibetan, Yi and Han, and analyze the differences and similarities of the bacteria.

Methods: The test subjects were selected from 2 Tibetan, 2 Yi and 3 Han populated places, respectively. Total 222 seniors (444 eyes) with dry eye were examined.

[Bacterial profiles in conjunctival sac of dry eyes and normal eyes in middle- and old-aged Yi populations].

Objective: To compare the bacterial profiles in conjunctival sac of dry eyes and normal eyes in Yi people aged 40 years or old.

Methods: A cross-sectional survey was conducted with standardized training and protocol. A total of 140 dry eyes of 70 individuals from Yi people in Jiulong county underwent ophthalmological examinations.

Comparative study of bacterial status from conjunctival sac of the elder Qiang minority and Han people with dry eye in Sichuan, China.

Aim: To compare the status of bacteria in the conjunctival sac from the elder Qiang minority and Han people with dry eyes in Sichuan, China.

Methods: Total of 54 elder Qiang people with dry eyes (108 eyes) were examined by cluster sampling. In the similar habitation region of Han people, 80 (160 dry eyes) Han people were analyzed as the control group.

[Bacterial profiles in conjunctival sac of middle-aged and elderly Qiang with dry eyes and normal eyes].

Objective: To compare the bacteria profiles in conjunctival sac of Qiang aged 40 years and over between those with dry eyes and those with normal eyes.

Methods: This survey was undertaken with a standardized protocol in Beichuan county. Ophthalmological examinations were performed on 54 individuals with dry eyes (108 eyes) and 52 individuals with normal eyes (104 eyes).

[Effects of travoprost on actin cytoskeleton and β-catenin in the human trabecular meshwork cells treated with Dexamethasone].

Objective: To investigate the effect of travoprost on changes of actin cytoskeletal and β-catenin protein in the cultured human trabecular meshwork (HTM) cells treated with dexamethasone (DEX).

Methods: It was a control experiment study. The HTM cells were cultured in vitro and divided into control group, DEX (1 × 10(-6) mol/L) group, travoprost (1 × 10(-6) mol/L) group, and DEX (1 × 10(-6) mol/L) plus travoprost (1 × 10(-6) mol/L) group.

Prevalence and causes of visual impairment and blindness in Sichuan province of China.

Aim: To describe the prevalence and causes of low vision and blindness in a population within Sichuan province in southwestern China.

Methods: A stratified, multi-phased and cluster probability sampling design was employed to enumerate 125641 participants from 40351 households within 38 counties/cities. Participants underwent a comprehensive eye examination, including standardized visual acuity (VA) tests using logarithm of the minimum angle resolution charts.

[A novel GJA8 mutation in a Chinese family with autosomal dominant congenital cataract].

Objective: To identify the mutations in the gap junction protein alpha3/alpha8 gene (GJA3 or GJA8) in the Chinese family with autosomal dominant congenital cataract (ADCC).

Methods: All subjects(5 family members and 100 unrelated control individuals)were undergone comprehensive ophthalmic examination, and genomic DNA was extracted from peripheral blood (5 mL). The exons and flanking introns of GJA3/GJA8 genes were amplified by polymerase chain reaction (PCR).