The bone is the most common metastatic site of breast cancer. Bone metastasis causes pain, pathologic fractures, and severely reduces the quality of life. Breast cancer causes osteolytic bone metastasis, which is dependent on osteoclast-mediated bone resorption.
View Article and Find Full Text PDFThis study investigates the anticancer effect of arctigenin (ATG), a natural lignan product of Arctium lappa L., in human breast cancer MDA-MB-231 cells. Results indicate that ATG inhibits MDA-MB-231 cell growth by inducing apoptosis in vitro and in vivo.
View Article and Find Full Text PDFMetal-free dyes (BP-1 to BP-3) containing a 9,10-dihydrophenanthrene unit in the spacer have been synthesized. The dye with the highest cell efficiency, BP-2, was used in combination with SQ2 for cosensitized DSSCs. The cosensitized DSSC in which the ratio of BP-2 and SQ2 is 8:2 (v/v) has a record high efficiency of 8.
View Article and Find Full Text PDFNew heteroleptic ruthenium complexes have been synthesized and used as the sensitizers for dye-sensitized solar cells (DSSCs). The ancillary bipyridine ligand contains rigid aromatic segments (fluorene-, carbazole-, or dithieno[3,2-b:2',3'-d]pyrrole-substituted bipyridine) tethered with a hydrophobic hexyl substituent. The conjugated aromatic segment results in significant bathochromic shift and hyperchromic effects in these complexes compared with Z907 (cis-[RuLL'(NCS)(2)]; L=4,4'-dicarboxylic acid-2,2'-bipyridine, L'=4,4'-dinonyl-2,2'- bipyridine).
View Article and Find Full Text PDFA new series of amphiphilic heteroleptic ruthenium(II) sensitizers with a fluorous bis-ponytailed bipyridine ancillary ligand, [Ru(H(2)dcbpy)(4,4'-bis(R(f)CH(2)OCH(2))-2,2'-bpy)(NCS)(2)] [where R(f) = HCF(2)CF(2) (CT4), C(3)F(7) (CT7), and HCF(2)CF(2)CF(2)CF(2) (CT8)], have been synthesized and fully characterized by UV/vis, visible emission, NMR, fast atom bombardment mass spectrometry, and cyclic voltammetric studies. Dye-sensitized solar cells (DSCs) based on these dyes exhibit efficiencies comparable with that of the standard cell based on N719. The conversion efficiency of a CT7- or CT8-based DSC is ~9% higher than that of Z907 with a nonfluorous bis-ponytailed bipyridine ancillary ligand.
View Article and Find Full Text PDFThe synthesis, electronic properties, and performance in dye-sensitized solar cells (DSSCs) of four cone-shaped organic dyes (ITD, ITD-Th, ITD-Hx, and ITD-OM) containing the isotruxene π-scaffold are reported. Selective substitution of the unsymmetrical isotruxene core with two diarylamino donors and one cyanocarboxylic acid acceptor was achieved by using a prefunctionalized dibromoisotruxene building block. The ortho-para-branched isotruxene core allows strong electronic couplings among the donors and the acceptor, leading to red-shifted absorption profiles with significant charge-transfer character.
View Article and Find Full Text PDFA detailed study of the synthesis and photophysical properties of a new series of dipolar organic photosensitizers that feature a 1,3-cyclohexadiene moiety integrated into the π-conjugated structural backbone has been carried out. Dye-sensitized solar cells (DSSCs) based on these structurally simple dyes have shown appreciable photo-to-electrical energy conversion efficiency, with the highest one up to 4.03 %.
View Article and Find Full Text PDFA novel series of dipolar organic dyes containing diarylamine as the electron donor, 2-cyanoacrylic acid as the electron acceptor, and fluorene and a heteroaromatic ring as the conjugating bridge have been developed and characterized. These metal-free dyes exhibited very high molar extinction coefficients in the electronic absorption spectra and have been successfully fabricated as efficient nanocrystalline TiO(2) dye-sensitized solar cells (DSSCs). The solar-energy-to-electricity conversion efficiencies of DSSCs ranged from 4.
View Article and Find Full Text PDFNew dipolar compounds incorporating a dithieno[3,2-b:2',3'-d]thiophene unit as the electron donor, an oligothiophene moiety as the conjugated spacer, and 2-cyanoacrylic acid as the electron acceptor have been synthesized. These nonarylamine type metal-free organic compounds have been successfully used as the sensitizers of dye-sensitized solar cells (DSSCs). The conversion efficiencies of the DSSCs range from 3.
View Article and Find Full Text PDFA series of donor-pi-acceptor-type organic dyes based on 1-alkyl-1H-imidazole spacers 1-5 have been developed and characterized. The two electron donors are at positions 4 and 5 of the imidazole, while the electron-accepting cyanoacrylic acid is incorporated at position 2 by a spacer-containing heteroaromatic rings, such as thiophene and thiazole. Detailed investigation on the relationship between the structure, spectral and electrochemical properties, and performance of DSSC is described here.
View Article and Find Full Text PDFTwo isomeric compounds (1 and 2) containing a dibenzo[f,h]thieno[3,4-b]quinoxaline core and two peripheral arylamines were synthesized. Solution-processed bulk heterojunction (BHJ) solar cells based on these sensitizers and [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) are reported. The cell fabricated from 1/67 wt % of PCBM exhibited a high power conversion efficiency of 1.
View Article and Find Full Text PDFA series of structurally simple dipolar light-harvesting organic dyes featuring 1,3-cyclohexadiene in the aromatic pi framework for dye-sensitized solar cells has been synthesized and characterized. The highest conversion efficiency of the DSSCs based on these dyes can reach up to 4.4%.
View Article and Find Full Text PDFNew metal-free dyes with a furan moiety in the conjugated spacer between the arylamine donor and the 2-cyanoacrylic acid acceptor have been synthesized, and high efficiency dye-sensitized solar cells were fabricated using these molecules as light-harvesting sensitizers.
View Article and Find Full Text PDFNew organic dyes that contain variable lengths of conjugation featuring alternating thiophene and fluorene segments have been synthesized and efficient nano-crystalline TiO2 based dye-sensitized solar cells were fabricated using these molecules as light-harvesting sensitizers.
View Article and Find Full Text PDFVersatile dyes based on benzothiadiazole and benzoselenadiazole chromophores have been developed that perform efficiently in dye-sensitized solar cells. Power conversion efficiency of 3.77% is realized for a dye in which charge recombination is probably hindered by the nonplanar charge-separated structure.
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