Publications by authors named "Yinan Ren"

ZnO whiskers have many applications, such as in medical and photocatalysis fields. In this study, an unconventional preparation approach is reported, realizing the in-situ growth of ZnO whiskers on TiZnC. The weak bonding between the layer of TiC-octahedron and the Zn-atom layers leads to the easy extraction of Zn atoms from TiZnC lattice points, resulting in the formation of ZnO whiskers on the TiZnC surface.

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Article Synopsis
  • After the publication of Gemstone-302, seven PD-(L)1 inhibitors were either launched or set to launch in China, but no direct comparisons of their effectiveness for treating squamous non-small cell lung cancer (sq-NSCLC) exist.* -
  • This study aimed to indirectly evaluate the efficacy of these treatments by analyzing phase III clinical trials for patients with advanced sq-NSCLC, using methods like Bayesian network meta-analysis to assess outcomes including overall survival (OS) and progression-free survival (PFS).* -
  • The results indicated that sugemalimab showed the best performance for both OS and PFS compared to other treatments, with strong evidence supporting its use in long-term survival benefits.*
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Background: We evaluated the cost-effectiveness of the screening in mainland China for Alzheimer's disease (AD) patients aged over 60.

Methods: Individuals in mainland China, received an initial screening by questionnaire on mental state, and those with scores deemed suspicious for AD were referred to diagnostic tests. A 9-state Markov model was developed to simulate the disease progression of a cohort of 100,000 subjects aging from 60 to 80.

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Objective: Results of CameL-sq has revealed the clinical benefits to patients with advanced squamous non-small-cell lung cancer (sq-NSCLC). This study aims to evaluate the cost-effectiveness of camrelizumab plus chemotherapy to treat sq-NSCLC from the perspective of the Chinese healthcare system.

Methods: We used a partitioned survival model with a lifetime horizon to evaluate the cost-effectiveness of camrelizumab plus chemotherapy vs.

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Objective: This study aimed to evaluate the cost-effectiveness of the colorectal cancer screening in China, and that when the screening was implemented in a specific region.

Methods: A 13-state Markov model was established to compare four screening protocols, including annual fecal immunochemical testing (FIT1), biennial fecal immunochemical testing (FIT2), electronic colonoscopy every 10 years (e-CSPY10), and electronic colonoscopy every 5 years (e-CSPY5), with no screening from the perspective of Chinese healthcare system. The model simulated the health states of a cohort of 100,000 average-risk individuals aging from 50 to 75.

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China has ~6 million patients with active epilepsy every year, around 60% of whom suffer from partial-onset seizures. Perampanel (PER) is a novel anti-epileptic drug for partial-onset seizures. PER has been included in the latest Chinese National Reimbursement Drug List (NRDL) in 2020.

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