Effect of pulmonary rehabilitation training on postoperative recovery in lung cancer patients undergoing thoracoscopic partial pulmonary resection: a meta-analysis.

Objective: To systematically analyze the impact of pulmonary rehabilitation (PR) on postoperative recovery of lung cancer patients undergoing thoracoscopic partial pulmonary resection.

Methods: This study has been registered with PROSPERO (CRD42024574965). A comprehensive search was conducted in PubMed, The Cochrane Library, Embase, Web of Science and CINAHL for literature on the effects of PR on postoperative rehabilitation in lung cancer patients undergoing thoracoscopic partial pulmonary resection, up to May 2024.

The impact of tax burden on welfare attitudes: Micro evidence from welfare states.

The attitudes of the general public with regard to social welfare are of crucial importance in determining the efficacy and stability of a nation's welfare system. The manner in which taxation is employed as a means of funding mechanism for welfare policies is of great consequence. Nevertheless, existing research on the subject of welfare attitudes has largely neglected the tax perspective, underscoring the need for investigations that bridge this gap and provide a more comprehensive understanding of the intertwined dynamics between taxation and public perception of social benefits.

A Guide to the Implementation and Design of Ex Vivo Perfusion Machines for Vascularized Composite Allotransplantation.

Background: Ex vivo machine perfusion (EVMP) is a versatile platform utilized in vascularized composite allotransplantation (VCA) to prolong preservation, salvage tissue, and evaluate graft viability. However, there is no consensus on best practices for VCA. This article discusses the common components, modifications, and considerations necessary for a successful VCA perfusion.

Real-world analysis of levetiracetam-associated rhabdomyolysis: insights from the FDA adverse event reporting system.

Background: Levetiracetam, a widely prescribed antiseizure medication, is recognized for its broad-spectrum efficacy, good tolerability, and minimal drug interactions. This study examines the association between levetiracetam and rhabdomyolysis, utilizing real-world data from the FDA Adverse Event Reporting System (FAERS) database to further elucidate its safety profile.

Methods: This study extracted adverse events related to levetiracetam from the FAERS database (Q1 2013 to Q1 2024).

Method of Motion Planning for Digital Twin Navigation and Cutting of Shearer.

To further enhance the intelligence level of coal mining faces and achieve the autonomous derivation, learning, and optimization of shearer navigation cutting, this paper proposes the methods of shearer digital twin navigation cutting motion planning based on the concept of shearer autonomous navigation cutting technology and intelligent coal mining face digital twins. This study includes the digital twin theory and the construction method of the shearer digital twin navigation cutting motion planning system based on this theory. Based on the digital twin theory, a shearer digital twin navigation cutting motion planning system was constructed.

Pressure Characteristics and Secondary Ignition Effects of Gas Produced in RDE Using Lignite and Anthracite/CH Fuel.

This study aims to address the energy efficiency release and environmental impact of coal dust in rotating detonation engines (RDEs) by monitoring the detonation characteristics of lignite and anthracite in methane gas-solid mixtures using high-precision sensor technology. Experimental results indicate that the peak detonation pressure of anthracite is 1.4% higher than that of lignite, and its detonation wave propagation speed is at least 5.

Experimental Study and Application Prospects of Coal Dust/Methane/Oxygen Pulse Detonation Performance: Coal Dust Equivalence Ratio and Types.

In order to achieve reliable application of coal in pulse detonation combustion chambers, this study explored the influence mechanism of equivalence ratio and coal type (lignite, anthracite) on the detonation characteristics of coal/methane/oxygen methane-solid two-phase fuel. A high-energy ignition device was used to ignite the preblast methane fuel, and the high-temperature and high-pressure energy generated directly initiated the detonation of coal/methane/oxygen methane-solid two-phase fuel. The experimental results are as follows: (1) The maximum detonation pressure of coal/methane/air fuel is positively correlated with the initial pressure.

Bexarotene Induce Differentiation of Myeloid-Derived Suppressor Cells through Arg-1 Signalling Pathway.

Background: Cellular therapy has emerged as a promising strategy to minimize the use of conventional immunosuppressive drugs and ultimately induce long-term graft survival. Myeloid-derived suppressor cells (MDSCs) can be used for immunosuppressive treatment of solid organ transplants.

Methods: Granular macrophage colony-stimulating factor (GM-CSF) and bexarotene, an X receptor-selective retinoid, were used for in vitro MDSC induction.

YiQi GuBen formula alleviates airway inflammation and airway remodeling in OVA-induced asthma mice through TLR4/NF-κB signaling pathway.

Background: We aim to investigate the effect of YiQi GuBen formula (YQGB) on airway inflammation and airway remodeling in the ovalbumin (OVA)-induced asthma model to further explore the potential mechanisms of YQGB in treating allergic asthma.

Methods: Mice were divided into five groups randomly (n = 10): the control group, OVA group, OVA + Dex (0.1 mg/kg) group, OVA + low-dose (1.

Design of Digital Twin Cutting Experiment System for Shearer.

This study presents an advanced simulated shearer machine cutting experiment system enhanced with digital twin technology. Central to this system is a simulated shearer drum, designed based on similarity theory to accurately mirror the operational dynamics of actual mining cutters. The setup incorporates a modified machining center equipped with sophisticated sensors that monitor various parameters such as cutting states, forces, torque, vibration, temperature, and sound.

Study on detonation characteristics of pulverized coal and evolution law of detonation residue.

This study explores the detonation characteristics and compositional changes of pulverized coal, focusing on its use in Rotary Detonation Wave (RDW) technologies. While pulverized coal has shown high fuel efficiency in RDW settings, transitioning from theory to practical detonation engineering presents substantial scientific and technical hurdles. A key issue is the reprocessing of detonation byproducts for in-situ coal mine gob filling, a topic that has received little attention.

Mechanistic insights into targeting caspase-3 activation and alveolar macrophage pyroptosis by Ephedra and bitter almond compounds for treating pediatric pneumonia via network pharmacology and bioinformatics.

This study investigates the molecular mechanism of Ma Huang-Ku Xing Ren, a traditional Chinese medicine formula, in treating pediatric pneumonia. The focus is on the regulation of caspase-3 activation and reduction of alveolar macrophage necrosis through network pharmacology and bioinformatics analyses of Ephedra and bitter almond components. Active compounds and targets from ephedrine and bitter almond were obtained using TCMSP, TCMID, and GeneCards databases, identifying pediatric pneumonia-related genes.

YiQi GuBen capsule alleviates OVA-induced asthma through improving mitochondrial dysfunction.

This study aims to explore the effect of YiQi GuBen capsule on improving mitochondrial dysfunction in an animal model of asthma. The mice ( = 8) were divided into four groups including control (NC), ovalbumin (OVA), dexamethasone (OVA + DEX), and YiQi GuBen (OVA + YQGB) groups. Firstly, we established an OVA-induced mouse asthma model except for the NC group, which then were treated with dexamethasone and YiQi GuBen capsule.

Learning to Guide Particle Search for Dynamic Multiobjective Optimization.

Dynamic multiobjective optimization problems (DMOPs) are characterized by multiple objectives that change over time in varying environments. More specifically, environmental changes can be described as various dynamics. However, it is difficult for existing dynamic multiobjective algorithms (DMOAs) to handle DMOPs due to their inability to learn in different environments to guide the search.

Design and Experimental Results of a Three-Dimensional Force Sensor for Shearer Cutting Pick Force Monitoring.

The main focus of this work is the design and development of a three-dimensional force sensor for the cutting pick of a coal mining shearer's simulated drum. This sensor is capable of simultaneously measuring the magnitude of force along three directions of the cutting pick during the cutting sample process. The three-dimensional force sensor is built based on the strain theory of material mechanics, and reasonable structural design is implemented to improve its sensitivity and reduce inter-axis coupling errors.

Association between parental occupational exposure and the risk of asthma in offspring: A meta-analysis and systematic review.

Background: Previous epidemiological studies have shown inconsistent results regarding the relation between the risk of asthma in offspring and parental occupational exposure. Therefore, we conducted a comprehensive and systematic collection of currently available epidemiological data to quantify the correlation between the 2.

Methods: Related studies published before March 2023 were identified through searches of the Cochrane Library, Embase, PubMed, and Web of Science databases.

Online Sparse Representation Clustering for Evolving Data Streams.

Data stream clustering can be performed to discover the patterns underlying continuously arriving sequences of data. A number of data stream clustering algorithms for finding clusters in arbitrary shapes and handling outliers, such as density-based clustering algorithms, have been proposed. However, these algorithms are often limited in their ability to construct and merge microclusters by measuring the Euclidean distances between high-dimensional data objects, e.

Telomerase reverse transcriptase restores pancreatic microcirculation profiles and attenuates endothelial dysfunction by inhibiting mitochondrial superoxide production: A potential target for acute pancreatitis therapy.

Background: Acute pancreatitis (AP) is a potentially lethal disease related to prominent microcirculation dysfunction. Pancreatic microvascular endothelial dysfunction enhances oxidative stress with tissue damage. Increased superoxide production disrupts endothelial junction integrity and increases endothelial permeability.

Effects of tail nerve electrical stimulation on the activation and plasticity of the lumbar locomotor circuits and the prevention of skeletal muscle atrophy after spinal cord transection in rats.

Introduction: Severe spinal cord injury results in the loss of neurons in the relatively intact spinal cord below the injury area and skeletal muscle atrophy in the paralyzed limbs. These pathological processes are significant obstacles for motor function reconstruction.

Objective: We performed tail nerve electrical stimulation (TNES) to activate the motor neural circuits below the injury site of the spinal cord to elucidate the regulatory mechanisms of the excitatory afferent neurons in promoting the reconstruction of locomotor function.

Angiotensin-(1-7) ameliorates intestinal barrier dysfunction by activating the Keap1/Nrf2/HO-1 signaling pathway in acute pancreatitis.

Background: Intestinal barrier dysfunction is a serious complication associated with acute pancreatitis (AP). Angiotensin (Ang)-(1-7) plays a protective role in the intestinal barrier, but the underlying mechanism remains clear. This study investigated the impact of Ang-(1-7) on AP-induced intestinal dysfunction and its involvement in the Keap1/Nrf2/HO-1 pathway.

Microbiome Characteristics in Early Threatened Miscarriage Study (MCETMS): a study protocol for a prospective cohort investigation in China.

Introduction: Studies have suggested that the vaginal microbiome and gut microbiome are involved in pregnancy-related diseases, but little exploration of the link with early miscarriage or threatened miscarriage (TM) has been done. Whether the characteristics of the vaginal microbiome and gut microbiome in early pregnancy are related to TM and early pregnancy outcomes remains unclear.

Methods And Analysis: The Microbiome Characteristics in Early Threatened Miscarriage Study (MCETMS) is a prospective investigation that will recruit 326 pregnant women with early TM.

Dynamic Ensemble Selection for Imbalanced Data Streams With Concept Drift.

Ensemble learning, as a popular method to tackle concept drift in data stream, forms a combination of base classifiers according to their global performances. However, concept drift generally occurs in local data space, causing significantly different performances of a base classifier at different locations. Thus, employing global performance as a criterion to select base classifier is inappropriate.