Functional angiography-derived index of microcirculatory resistance validated with microvascular obstruction in cardiac magnetic resonance after STEMI.

Introduction And Objectives: The index of microcirculatory resistance (IMR) measured after primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) is associated with microvascular obstruction (MVO) and adverse clinical events. To evaluate MVO after successful primary PCI for STEMI without pressure wires or hyperemic agents, we investigated the feasibility and usefulness of functional angiography-derived IMR (angio-IMR).

Methods: The current study included a total of 285 STEMI patients who underwent primary PCI and cardiac magnetic resonance (CMR).

Functional Coronary Angiography-Derived Index of Microcirculatory Resistance in Patients With ST-Segment Elevation Myocardial Infarction.

Objectives: The aim of this study was to evaluate the diagnostic accuracy and prognostic implications of angiography-derived index of microcirculatory resistance (angio-IMR) in patients with ST-segment elevation myocardial infarction (STEMI).

Background: The index of microcirculatory resistance (IMR) is a reliable invasive measure of coronary microvascular dysfunction in patients with STEMI. A functional coronary angiography-derived method to estimate IMR is a wire- and hyperemic agent-free alternative to IMR.

The acute effects of temperature variability on heart rate variability: A repeated-measure study.

Background: The impacts of temperature variability on cardiac autonomic function remain unclear.

Objective: To explore the short-term associations between daily temperature variability and parameters of heart rate variability (HRV).

Methods: This is a repeated-measure study among 78 eligible participants in Shanghai, China.

Size-fractionated particulate air pollution and myocardial infarction emergency hospitalization in Shanghai, China.

Background: Fine particulate matter (PM) air pollution has been associated with increased risks of acute myocardial infarction (AMI), but it remains unknown about the potentially differentiated effects of size-fractionated particulate matter on AMI risk.

Objective: To identify the specific size ranges that dominate the effects of particulate matter on AMI onset.

Methods: We conducted a time-series study in Shanghai, China from January 2014 to December 2018.

Fine particulate matter constituents and heart rate variability: A panel study in Shanghai, China.

Background: Short-term exposure to fine particulate matter (PM) has been associated with reduced heart rate variability (HRV), an established indicator of cardiac autonomic function, but it remains uncertain which specific constituents of PM had key impacts.

Objective: To examine the short-term associations between various PM constituents and HRV measures.

Methods: We conducted a retrospective panel study among 78 participants who received repeated 24-h electrocardiogram testing in Shanghai, China from 2015 to 2019.

Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs.

Overcoming multidrug resistance has always been a major challenge in cancer treatment. Recent evidence suggested epithelial-mesenchymal transition plays a role in MDR, but the mechanism behind this link remains unclear. We found that the expression of multiple ABC transporters was elevated in concordance with an increased drug efflux in cancer cells during EMT.

Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin.

Many gastrointestinal diseases exhibit a protracted and aggravated inflammatory response that can lead to hypercytokinaemia, culminating in extensive tissue damage. Recently, angiopoietin-like 4 (ANGPTL4) has been implicated in many inflammation-associated diseases. However, how ANGPTL4 regulates colonic inflammation remains unclear.

Enhanced Photocatalytic Activity of CdS-Decorated TiO₂/Carbon Core-Shell Microspheres Derived from Microcrystalline Cellulose.

The fabrication of reusable and biodegradation materials from renewable resources such as cellulose is essential for a sustainable world. The core-shell structured CdS-decorated TiO₂/Carbon microspheres (CdS/TiO₂/Carbon MS) photocatalyst was synthesized with controlled hydrolysis and a novel sonochemical method. It was prepared by using crosslinked microcrystalline cellulose as the core, tetrabutyl titanate as the titania source and CdS as the photosensitizer.

A comparison of the efficacy of surgical renal denervation and pharmacologic therapies in post-myocardial infarction heart failure.

Objective: Although renal denervation (RD) has been shown to be effective in treating post- myocardial Infarction (MI) heart failure (HF) in animal models and clinical trials, its utility as a standalone treatment without traditional drug treatment for post-MI HF still needs to be investigated.

Methods: Rats were randomly assigned into seven experimental groups: N group (control group with no MI and no RD, n = 10), MI group (MI, n = 20), RD group (renal denervation, n = 10), RD-3d+MI group (RD performed three days before MI, n = 15), β-blocker-3d+MI group (Metoprolol treated three days before MI, n = 15), ACEI-3d+MI group (Perindopril treated three days before MI, n = 15), and ARB-3d+MI group (Losartan treated three days before MI, n = 15). Cardiac function, autonomic nervous system parameters, and neuroendocrine activities were evaluated 8 weeks post MI.

Effect of C/N ratios on the performance of earthworm eco-filter for treatment of synthetics domestic sewage.

Purpose: The performances of filter systems that use earthworms and plants, combined with earthworm eco-filter (EE) systems in treating synthetic domestic sewage (SDS) with different C/N ratios, were investigated for a 9-month period.

Methods: The effects of the combination of filters, earthworms, plants, as well as the combination of earthworms and plants on SDS nutrient removal efficiency were separately investigated to select the optimum system for treating SDS. The results of the current study could be used to determine how treatment performance responds to different C/N ratios and to explain and predict the performance of an operating EE system.

Evaluation of Takayasu arteritis activity by delayed contrast-enhanced magnetic resonance imaging.

Background: To measure and assess the disease activity of Takayasu arteritis (TA) quantitatively by magnetic resonance angiography (MRA).

Methods: Twenty-six Chinese TA patients were divided into an active group and an inactive group. All patients underwent delayed contrast-enhanced MRI.

Radiographic verification of pedicle screw pilot hole placement in thoracic spine using Kirschner wires versus spiral wires.

Objective: To evaluate the feasibility of the pedicle screw pilot holes placement in thoracic spine using the spiral wires as the guide pin.

Methods: The pedicle screw pilot holes were drilled within the center of the pedicle and the lateral and medial pedicle walls were violated in 9 human dried thoracic vertebrae. Kirschner wires or spiral wires were separately placed in the holes, and then the posteroanterior and lateral radiographs were taken.

Prosthetic replacement in treatment of subcapital femoral neck fractures in the elderly.

Objective: To compare the results of femoral head replacement (FHR) and total hip replacement (THR) in treatment of subcapital femoral neck fractures (SFNF).

Methods: Between May 1987 and July 1998, 56 elderly patients (6 5-90 years; average 73.5 years) with SFNF were treated with prosthetic replacement.