Publications by authors named "Yin-xia Zhao"
Article Synopsis
- - Hepatitis B virus (HBV) is a major global health issue, infecting around 360 million people and causing approximately 1 million deaths each year due to severe liver disease and liver cancer, with current treatments often failing to provide a complete cure.
- - This study found a significant positive correlation between serum sphingosine-1-phosphate (S1P) levels and HBV DNA in patients with chronic hepatitis B, indicating a connection between the virus and liver injury.
- - The research identified USF1 as a key factor that regulates the expression of sphingosine kinase 1 (SphK1) during HBV infection, suggesting that the SphK1-S1P pathway could be a promising
Viral myocarditis (VMC) is a cardiac disease associated with myocardial inflammation and injury induced by virus infection. Cardiomyocytes have recently been regarded as key players in eliciting and modulating inflammation within the myocardium. Kruppel-like factor 10 (KLF10) is a crucial regulator of various pathological processes and plays different roles in a variety of diseases.
View Article and Find Full Text PDF[Magnetic resonance imaging versus DR for whole spine imaging in patients with degenerative spinal disease].
Nan Fang Yi Ke Da Xue Xue Bao
September 2017
Objective: To assess the quality of whole spine images obtained by DR and magnetic resonance imaging (MRI) and analyze the whole spinal imaging sagittal parameters for standing DR and supine MRI.
Methods: Sixty-one patients aged 49.9∓17.
[Correlation between vertebral bone marrow fat and abdomen fat: a prospective study].
Nan Fang Yi Ke Da Xue Xue Bao
February 2016
Objective: To investigate the correlation between the lumbar bone marrow fat and abdominal fat.
Methods: A total of 68 individuals (32 men and 36 women, aged 21-74 years with a median of 49.5 years) were included in this study.
Objective: To further reveal the chemical constituents of Polypodium hastatum, volatile components from this plant were investigated.
Methods: The volatile components were extracted under reflux from the whole plant of Polypodium hastatum, and then analyzed qualitatively and quantitatively by GC-MS.
Results: 60 volatile components were detected and of all components detected, the structures and relative contents of 34 volatile compounds were elucidated.
Many recent studies have suggested that bergapten (BP), a class of native compound with numerous biological activities such as anti-resorptive properties, may exert protective effects against postmenopausal bone loss. However, it remains unknown whether BP regulates or improves the osteogenic function of bone marrow stromal cells (BMSCs) in the treatment and prevention of osteoporosis. In our study, BMSCs were cultured in osteogenic induction medium with the addition of BP for 2 weeks and an ovariectomized mouse model of osteoporosis was used to investigate the anti-resorptive effect of BP by gavage administration for 3 months.
View Article and Find Full Text PDFObjective: To observe the expression of Toll-like receptor 8 (TLR8) in human cervical cancer cell-line HeLa cells, and the effects of TLR8 agonist CL075 on the survival and proliferation of HeLa cells.
Methods: PCR and RT-PCR were used to detect the expression of TLR8 in 13 cancer cell lines, and the expression of COX-2, Bcl-2, VEGF mRNA in the HeLa cells stimulated by TLR8 agonist CL075 were also measured by RT-PCR. Immunofluorescence technique was used to determine the exact location of TLR8 in the cells.