B cell subsets were associated with prognosis in elderly patients with community acquired pneumonia.

Background: The role of B cell subsets remained to be elucidated in a variety of immune diseases, though which was used as an effective biomarker for anti-inflammatory or antiviral response. This study aimed to evaluate the early changes of B cell subtypes distribution in elderly patients with community acquired pneumonia (CAP), as well as the association between B cell subtypes and prognosis.

Methods: This prospective study included elderly patients with CAP, severe CAP (sCAP) and healthy elderly subjects between April 2016 and March 2018.

A Multistrategy Artificial Bee Colony Algorithm Enlightened by Variable Neighborhood Search.

Artificial bee colony (ABC) has a good exploration ability against its exploitation ability. For enhancing its comprehensive performance, we proposed a multistrategy artificial bee colony (ABCVNS for short) based on the variable neighborhood search method. First, a search strategy candidate pool composed of two search strategies, i.

An Enhanced Differential Evolution Algorithm Based on Multiple Mutation Strategies.

Differential evolution algorithm is a simple yet efficient metaheuristic for global optimization over continuous spaces. However, there is a shortcoming of premature convergence in standard DE, especially in DE/best/1/bin. In order to take advantage of direction guidance information of the best individual of DE/best/1/bin and avoid getting into local trap, based on multiple mutation strategies, an enhanced differential evolution algorithm, named EDE, is proposed in this paper.

[Relationship between mutations of epidermal growth factor receptor gene and clinicopathologic features of non-small cell lung cancers].

Objective: To explore the relationship between the mutations of epidermal growth factor receptor (EGFR) gene and clinicopathological characteristics in patients with non-small cell lung cancers (NSCLC).

Methods: Paraffin-embedded tissue specimens were obtained from 1444 patients with NSCLC. The genomic DNA was extracted.

[Comparison study on the diagnosis of erectile dysfunction with color Doppler ultrasonography and nocturnal electrobioimpedance volumetric assessment].

Objective: To study the diagnostic value of color Doppler ultrasonography(CDUS) and nocturnal electrobioimpedance volumetric assessment (NEVA) in the assessment of erectile dysfunction (ED) and in differentiating the causes of ED.

Methods: CDUS and NEVA were performed in the 45 patients with ED. The patients were classified into 3 groups according to their results of CDUS, and compared all parameters of NEVA between each two groups, and then studied the correlation between CDUS and NEVA in the assessment of ED.