Publications by authors named "Yin-Yee Tey"
Article Synopsis
- - The study investigated the prevalence and contributing factors of female sexual dysfunction among women aged 50 and older in a Malaysian outpatient clinic, using a self-administered questionnaire based on the Female Sexual Function Index.
- - Out of 263 participants, 68.8% reported experiencing female sexual dysfunction, with the highest issues in sexual desire (85.2%) and satisfaction (74.9%), while factors such as Indian ethnicity and less frequent sexual intercourse were linked to higher dysfunction risks.
- - The findings conclude that a significant portion of middle-aged women struggle with sexual dysfunction, highlighting the need for further research and interventions to address this issue.
Heritability of major depressive disorder (MDD) is between 36 and 44%, suggesting that up to nearly half of the phenotypic variability is attributable to genes. A number of genetic polymorphisms have been shown to predispose certain individuals to depression. Of particular interest are the polymorphisms of the vitamin D receptor (VDR) gene.
View Article and Find Full Text PDFA total of 201 patients with major depressive disorder from four hospitals in Malaysia were followed up for 5 years to determine the prognostic factors of recurrent major depressive disorder that could potentially contribute to improving the management of MDD patients. For each individual patient, at the time of recruitment as part of a case-control study, information was collected on recent threatening life events, personality and social and occupational functioning, while blood samples were collected to genotype single nucleotide polymorphisms of vitamin D receptor (VDR), zinc transporter-3 (ZnT3), dopamine transporter-1 (DAT1), brain-derived neurotropic factor (BDNF), serotonin receptor 1A (HT1A) and 2A (HT2A) genes. Kaplan-Meier and Cox-regression were used to estimate hazard functions for recurrence of major depressive disorder.
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