Publications by authors named "Yin-Tian Zhang"
[Correlation between U2AF1 Gene Mutation Characteristics and Clinical Manifestations and Prognosis in Patients with Myelodysplastic Syndrome].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2020
Article Synopsis
- The study aimed to analyze the relationship between U2AF1 gene mutations and clinical outcomes in patients with myelodysplastic syndromes (MDS).
- Approximately 11.3% of the 203 MDS patients studied had U2AF1 mutations, with a higher incidence in males, but no significant differences in prognosis or clinical features were found between mutated and non-mutated groups.
- The research highlights that U2AF1 mutations do not seem to significantly impact overall survival, transformation to acute myeloid leukemia, or response to treatment with hypomethylating agents.
[Clinical characteristics of hemophagocytic syndrome: analysis of 46 cases].
Nan Fang Yi Ke Da Xue Xue Bao
June 2018
Objective: To analyze the clinical manifestations, laboratory findings, treatment and prognosis of patients with hemophagocytic syndrome (HPS).
Methods: A retrospective study was carried out to analyze the underlying disease, clinical characteristics, laboratory findings and outcomes of 46 patients with HPS.
Results: This cohort included 19 cases of HPS secondary to cancer, 11 cases of HPS secondary to infection, 10 cases of suspected malignant lymphoma based on PET-CT findings (without biopsy), and 6 cases of unknown etiology.