Publications by authors named "Yin-Ping Qiu"
Article Synopsis
- - The study focused on creating a real-time risk prediction model for extrauterine growth retardation (EUGR) in very preterm infants, utilizing data from 2,514 infants split into training and validation sets.
- - Key predictors, including birth weight, small for gestational age, and others, were identified and used in a logistic regression model, with a nomogram visualization to help assess risk.
- - The model demonstrated strong predictive ability, achieving ROC curve areas of 83.1% and 84.6% for the training and validation sets, respectively, and indicating good calibration and clinical applicability for risk assessment.
Background: With the increasing survival rate of smaller newborns and twins, previous growth curves may not accurately assess the growth of extremely preterm infants (EPIs). Our study aimed to establish birth weight percentile curves for singletons and twins in EPIs from China and the USA and compare the differences between them.
Methods: In China, EPIs were from 31 provinces, from 2010 to 2021.
Background: Hyperglycemia in pregnancy (HGP) has generally been considered a risk factor associated with adverse outcomes in offspring, but its impact on the short-term outcomes of very preterm infants remains unclear.
Methods: A secondary analysis was performed based on clinical data collected prospectively from 28 hospitals in seven regions of China from September 2019 to December 2020. According to maternal HGP, all infants were divided into the HGP group or the non-HGP group.
Article Synopsis
- NEC is a serious illness that mostly affects premature babies, showing up usually after they are a week old.
- This study looked at data from over 2,500 premature babies to understand the causes of late-onset NEC and how it affects their health in the short term, especially focusing on their nutrition.
- Results showed that babies with late-onset NEC faced more health issues like anemia and required more treatments, had slower weight gain, and breastfeeding rates were lower among them.
Background: To analyze the real-world growth pattern of very premature infants (VPI) with small for gestational age (SGA) after birth by using the ΔZ value of weight at discharge.
Methods: The clinical data were collected from 28 hospitals in China from September 2019 to December 2020. They were divided into the EUGR(Extrauterine Growth Restriction) and the non-EUGR group according to the criterion of ΔZ value of weight at discharge < -1.
Objectives: The management of enteral nutrition in very preterm infants (VPIs) is still controversial, and there is no consensus on the optimal time point after birth at which enteral nutrition can be started. The aim of this study was to investigate the effect of early initiation of enteral nutrition on the short-term clinical outcomes of VPIs.
Methods: Data of infants (n = 2514) born before 32 wk of gestation were collected from 28 hospitals located in seven different regions of China.
Background: The incidence of extrauterine growth retardation (EUGR) varies considerably in different countries due to the distinct definitions and inclusion criteria of individual studies. Most studies included small for gestational age (SGA) very preterm infants (VPIs), resulting in a higher incidence of EUGR. Experts have suggested the accurate definition of "EUGR" in SGA infants is not "true EUGR".
View Article and Find Full Text PDFObjective: To investigate the incidence and related factors of extrauterine growth retardation (EUGR) and "true EUGR" in very preterm infants (VPI) from different regions of China.
Materials And Methods: Clinical data of VPI were prospectively collected from 28 hospitals in seven different regions of China from September 2019 to December 2020. The infants were divided into a small for gestational age (SGA) group or non-SGA group at birth, with non-SGA infants at 36 weeks of gestation or at discharge being further divided into a EUGR group or a non-EUGR group.
Objective: Nutritional deficiency soon after birth is a risk factor of chronic lung disease (bronchopulmonary dysplasia, BPD). Afflicted infants are further prone to inadequate growth during hospitalization (extrauterine growth restriction, EUGR). This multi-center retrospective study investigated risk factors of EUGR, specifically in very preterm infants with BPD.
View Article and Find Full Text PDFObjectives: To investigate the incidence of extrauterine growth retardation (EUGR) and its risk factors in very preterm infants (VPIs) during hospitalization in China.
Methods: A prospective multicenter study was performed on the medical data of 2 514 VPIs who were hospitalized in the department of neonatology in 28 hospitals from 7 areas of China between September 2019 and December 2020. According to the presence or absence of EUGR based on the evaluation of body weight at the corrected gestational age of 36 weeks or at discharge, the VPIs were classified to two groups: EUGR group (=1 189) and non-EUGR (=1 325).
Background: We retrospectively investigated incidence, morbidity, and mortality of neonatal necrotizing enterocolitis in China, with special emphasis on determining the predictors of necrotizing enterocolitis associated mortality.
Methods: We identified neonates as having necrotizing enterocolitis if they met the accepted diagnostic criterion. Data pertaining to antenatal period, labor and birth, and the postnatal course of illness were collected.
Article Synopsis
- * 744 neonates died in 26 NICUs, representing 1.2% of admissions, with preterm deaths being predominant (59.3%), largely due to pulmonary diseases and infections.
- * A significant number of deaths occurred after medical care was withdrawn, often due to parents' concerns about long-term outcomes, highlighting the need for better evaluation and communication regarding treatment options.
Article Synopsis
- The study investigated the short-term outcomes of extremely low birth weight (ELBW) infants in neonatal intensive care units (NICUs) across mainland China, finding that out of 258 infants admitted, the overall survival rate at discharge was 50%.
- Key risk factors for mortality included a birth weight under 750 g and a gestational age less than 28 weeks, while being small for gestational age provided some protection; common complications included respiratory distress syndrome and patent ductus arteriosus.
- This research marks the first comprehensive survey of ELBW infant outcomes in China, highlighting significant regional differences in survival rates and various health challenges faced during NICU stays.
[Effect of jinfu kang to experimental precancerous colon lesions and urinary metabolites in rat].
Zhongguo Zhong Yao Za Zhi
November 2008
Objective: : To profile urinary metabolite variations from 1, 2-dimethylhydrazine (DMH)-induced precancerous colon rats, Jinfu Kang treated rats and healthy controls.
Method: We used ethyl chloroformate derivatization and gas chromatography-mass spectrometry (GC-MS) based metabonomic method to analyze rat urines.
Result: The time-dependent variations of metabolite profile showed a progressive deviation of the metabolism in the model group from the initial pattern over time and a systemic recovery of the metabolism in the treatment group, which is consistent with the histological results.