Publications by authors named "Yin-Jie Ao"
The application of basic SMAS rhytidectomy and comprehensive SMAS rhytidectomy.
Medicine (Baltimore)
October 2024
Rhytidectomy has made great progress in the past 50 years, especially after the proposition of the concept of superficial musculoaponeurotic system (SMAS). Our previous research had classified SMAS rhytidectomy into basic SMAS rhytidectomy (B-SMAS) and comprehensive SMAS rhytidectomy (C-SMAS) according to whether the treatment of SMAS aponeurosis is combined with retaining ligament, fat pad, mimetic muscles, etc. The purpose of this paper is to compare the outcomes of the 2 methods.
View Article and Find Full Text PDFPoly-L-lactin acid (PLLA) has been widely used in the field of bio-medicine. In 2004, as an injectable material, PLLA was approved by the FDA to treat AIDS-related facial atrophy. Since then, several injectable stuffs containing PLLA have been approved for marketing in various countries and regions.
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- * A mouse model simulating laryngopharyngeal reflux was used to observe changes in the laryngeal epithelium after treatment with pepsin, revealing significant cell proliferation over time.
- * Results indicated that blocking Glut-1 reduced cell growth, and the study found increased expression of Glut-1 and H/K-ATPase proteins following pepsin exposure, suggesting their roles in laryngeal hyperplasia.
Article Synopsis
- * Recent research has started to recognize the importance of tumor stroma, particularly fibroblasts, in cancer development and progression beyond just the epithelial cells.
- * This study aims to review the effects of tobacco on fibroblasts and examine how these interactions influence cancer development.
Article Synopsis
- The study examines how Glut-1 and H/K-ATPase expressions affect the growth of human vocal cord leukoplakia cells after exposure to pepsin, a component of gastric juice.
- Researchers found that pepsin enhances the migration and proliferation of these cells while reducing their rate of apoptosis over time.
- The results suggest that higher Glut-1 levels may contribute to the progression of vocal cord leukoplakia to laryngeal carcinoma by increasing H/K-ATPase expression, leading to further damage to the laryngeal tissue.
Primary poorly differentiated small cell type neuroendocrine carcinoma of the hypopharynx.
Onco Targets Ther
February 2019
The incidence of primary poorly differentiated neuroendocrine carcinoma (PDNC) of the hypopharynx iŝ4%. However, the disease pathogenesis, natural history, and prognostic factors remain poorly understood. We report the case of a 66-year-old man who presented with multiple metastases from primary PDNC of the hypopharynx.
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