Publications by authors named "Yin-Chao Li"
Article Synopsis
- Oridonin is a substance taken from a Chinese herb called Rabdosia rubescens, and it helps control how cancer cells move and invade other areas.
- In a study, when cells were treated with oridonin, it made a specific protein (myosin IIA) work differently, which affected the cells' ability to move.
- The results showed that oridonin could be useful in stopping cancer cells from spreading by changing how myosin IIA interacts with another protein complex.
NMR spectra and structures of oridonin derivatives complexes with β-cyclodextrin.
Magn Reson Chem
September 2011
Complexations between three oridonin derivatives and β-cyclodextrin (βCD) were studied by nuclear magnetic resonance (NMR) method. Job's plots for complexes were depicted by (1)H NMR spectra chemical shifts, which proved the 1:1 stoichiometry inclusion complex formation between each derivative and βCD. Two-dimensional rotating frame overhauser effect spectroscopy (2D ROESY) support the above conclusion and also proved that ring A of each oridonin derivative deeply enters into hydrophobic cavity from the wider rim and the other parts are outside the cavity.
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