Dual intent view contrastive learning for knowledge aware recommender systems.

Knowledge-aware recommendation systems often face challenges owing to sparse supervision signals and redundant entity relations, which can diminish the advantages of utilizing knowledge graphs for enhancing recommendation performance. To tackle these challenges, we propose a novel recommendation model named Dual-Intent-View Contrastive Learning network (DIVCL), inspired by recent advancements in contrastive and intent learning. DIVCL employs a dual-view representation learning approach using Graph Neural Networks (GNNs), consisting of two distinct views: a local view based on the user-item interaction graph and a global view based on the user-item-entity knowledge graph.

Effect of different Agrobacterium rhizogenes strains on hairy root induction and analysis of metabolites in Physalis peruviana L.

Physalis peruviana L. (P. peruviana) is an edible medicinal plant rich in bioactive phenolics.

Export competitiveness network of Chinese provincial agricultural products: E volution, performance, and influencing factors.

The development of top-tier agricultural product bases and demonstration zones aims to propel Chinese agriculture into the global market, form international competitiveness, and advance to the high end of the global industrial and value chain. This study contributes to the existing literature by investigating the performance and factors influencing the competitiveness of Chinese agricultural product exports at the provincial level, using a complex network perspective, and offers recommendations for improvement. In this regard, the article uses agricultural product export data from 2015 to 2022 to create export competitiveness networks of Chinese provincial agricultural products.

Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2.

Aims: Magnesium ions (Mg) play an important role in promoting cartilage repair in cartilage lesions. However, no research has focused on the role of Mg combined with microfracture (MFX) in hyaline-like cartilage repair mediated by cartilage injury. This study aimed to investigate the beneficial effects of the combination of MFX and Mg in cartilage repair.

Understanding pollutant-driven shifts of antibiotic resistome in activated sludge: A lab-scale study.

Non-antibiotic pollutants have been identified as contributors to the development of antibiotic resistance across various environments. Wastewater treatment plants, recognized as hotspots for antibiotic resistance genes (ARGs), have received extensive attention regarding the mechanisms driving resistance changes in activated sludge. However, the specific impacts of heavy metals and aromatic organics-common pollutants in industrial wastewater-on the resistome of activated sludge, as well as the underlying mechanisms driving these effects, remain underexplored.

Control of HS synthesis by the monomer-oligomer transition of OsCBSX3 for modulating rice growth-immunity balance.

Hydrogen sulfide (H2S) is recognized as an important gaseous signaling molecule, similar to nitric oxide and carbon monoxide. However, the synthesis mechanism of H2S and its role in enhancing rice resistance to Xanthomonas oryzae pv. oryzicola (Xoc) and Xanthomonas oryzae pv.

A novel lncRNA PDG1 targets NADP-ME to modulate TCA cycle and JH in Aspongopus chinensis diapause.

Diapause is essential for insect survival under adverse environmental conditions and plays a crucial role in regulating reproduction. However, the role of long non-coding RNAs (lncRNAs) in this process remains unclear. In this study, we investigated the function of lncRNAs in the diapause of Aspongopus chinensis.

Neurophysiological data augmentation for EEG-fNIRS multimodal features based on a denoising diffusion probabilistic model.

Background And Objective: The hybrid brain computer interfaces (BCI) combining electroencephalogram (EEG) and functional near-infrared spectroscopy (fNIRS) have attracted extensive attention for overcoming the decoding limitations of the single-modality BCI. With the deepening application of deep learning approaches in BCI systems, its significant performance improvement has become apparent. However, the scarcity of brain signal data limits the performance of deep learning models.

Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder. Antiamyloid antibody treatments modestly slow disease progression in mild dementia due to AD. Emerging evidence shows that homeostatic dysregulation of the brain immune system, especially that orchestrated by microglia, plays an important role in disease onset and progression.

Construction of geriatric hypoalbuminemia predicting model for hypoalbuminemia patients with and without pneumonia and explainability analysis.

Background And Objectives: Pneumonia portrays a critical health concern in geriatrics. Geriatric pneumonia can lead to changes on other complications, in which hypoalbuminemia is a common complication. However, few studies have looked at the impact of pneumonia on the course of hypoalbuminemia and predicting.

A Chiral Sensing Platform Based on a Starfish-Shaped AuCu Alloy for Chiral Analysis.

Designing alloys with intrinsic chirality for chiral analysis is an interesting subject, since most alloys are achiral. Here, a starfish-shaped AuCu alloy is facilely prepared through simultaneous reduction of chloroauric acid (HAuCl) and copper chloride (CuCl) by l-ascorbic acid (l-AA). The resultant AuCu alloy exhibits fascinating chirality due to the chiral lattice distortion generated in the alloy.

Construction of N-E bonds via Lewis acid-promoted functionalization of chromium-dinitrogen complexes.

Direct conversion of dinitrogen (N) into N-containing compounds beyond ammonia under ambient conditions remains a longstanding challenge. Herein, we present a Lewis acid-promoted strategy for diverse nitrogen-element bonds formation from N using chromium dinitrogen complex [Cp*(IPrMe)Cr(N)]K (1). With the help of Lewis acids AlMe and BF, we successfully trap a series of fleeting diazenido intermediates and synthesize value-added compounds containing N-B, N-Ge, and N-P bonds with 3 d metals, offering a method for isolating unstable intermediates.

CK-666 exerts anticancer effects by regulating autophagy, tunneling nanotubes and extracellular vesicles formation.

CK-666, an inhibitor of the actin-related protein complex 2/3 (Arp2/3), can suppress lamellipodia formation and cell migration. However, research on its application in tumor therapy is still limited. Using RNA-seq, we clustered and analyzed the functions of differentially expressed mRNAs in CK-666-treated tumor cells.

Sirolimus as a repurposed drug for tendinopathy: A systems biology approach combining computational and experimental methods.

Background: Effective drugs for tendinopathy are lacking, resulting in significant morbidity and re-tearing rate after operation. Applying systems biology to identify new applications for current pharmaceuticals can decrease the duration, expenses, and likelihood of failure associated with the development of new drugs.

Methods: We identify tendinopathy signature genes employing a transcriptomics database encompassing 154 clinical tendon samples.

DCFE-YOLO: A novel fabric defect detection method.

Accurate detection of fabric defects is crucial for quality control in the textile industry. However, the task of fabric defect detection remains highly challenging due to the complex textures and diverse defect patterns. To address the issues of inaccurate localization and false positives caused by complex textures and varying defect sizes, this paper proposes an improved YOLOv8-based fabric defect detection method.

A discrete choice experiment on Chinese parents' preferences of vaccine schedules against six childhood infectious diseases.

Background: China's Expanded Program on Immunization (EPI) provides vaccinations against 12 vaccine preventable diseases (VPDs) at no cost to families. For some VPDs, parents may opt to substitute equivalent non-program vaccines, including combination vaccines, for EPI vaccines; substitute vaccines must be paid for by the family. Although parents have several choices for vaccinating their children, their preferences for vaccines and immunization schedules have not been systematically evaluated.

A pan-genome perspective on the evolutionary dynamics of polyphyly, virulence, and antibiotic resistance in serovar Mbandaka highlights emerging threats to public health and food safety posed by cloud gene families.

serovar Mbandaka, a prevalent foodborne pathogen, poses a threat to public health but remains poorly understood. We have determined the phylogenomic tree, genetic diversity, virulence, and antimicrobial resistance (AMR) profiles on a large genomic scale to elucidate the evolutionary dynamics within the Mbandaka pan-genome. The polyphyletic nature of this serovar is characterized by two distinct phylogenetic groups and inter-serovar recombination boundaries, that potentially arising from recombination events at the H2-antigen loci.

Evaluating Intervention Reporting in Nursing Journal RCTs Using the TIDieR Checklist: A Cross-Sectional Study.

Aim: To assess the completeness of intervention reporting in randomised controlled trials (RCTs) published in nursing journals based on the Template for Intervention Description and Replication (TIDieR) checklist.

Design: A cross-sectional study.

Methods: RCTs published in English in nursing journals between January 2022 and December 2022 were identified through PubMed.

Delay Minimization for BAC-NOMA Offloading in UAV Networks.

The rapid deployment and enhanced communication capabilities of unmanned aerial vehicles (UAVs) have enabled numerous real-time sensing applications. These scenarios often necessitate task offloading and execution under stringent transmission delay constraints, particularly for time-critical applications such as disaster rescue and environmental monitoring. This paper investigates the improvement of MEC-based task offloading services in energy-constrained UAV networks using backscatter communication (BackCom) with non-orthogonal multiple access (BAC-NOMA).

Abamectin Causes Neurotoxicity in Zebrafish Embryos.

Abamectin is an insecticide, miticide and nematicide that has been extensively used in agriculture for many years. The excessive use of abamectin inevitably pollutes water and soil and might even cause adverse effects on aquatic biota. However, it is currently unclear how abamectin exposure causes neurotoxicity in aquatic organisms.

Investigating the Impact of Circulating MicroRNAs on Knee and Hip Osteoarthritis: Causal Links, Biological Mechanisms, and Drug Interactions.

Osteoarthritis (OA), particularly in the knee and hip, poses a significant global health challenge due to limited therapeutic options. To elucidate the molecular mechanisms of OA and identify potential biomarkers and therapeutic targets, we utilized genome-wide association studies (GWAS) and cis-miRNA expression quantitative trait loci (cis-miR-eQTL) datasets to identify miRNAs associated with OA, revealing 16 that were linked to knee OA and 21 to hip OA. Among these, hsa-miR-1303 was significantly upregulated in both knee and hip OA (IVW: = 6.

Synthesis of Highly Expandable Poly(methacrylimide) (PMI) Precursor Beads Through Optimized Suspension Polymerization of MAA-MAN-tBMA Copolymers.

Bead-foaming technology effectively addresses production cycles, polymerization control, and cellular structure defects in conventional bulk foaming, especially in high-performance PMI foams. In this work, highly expandable PMI beads were synthesized based on the aqueous suspension polymerization of methacrylic acid-methacrylonitrile-tert-butyl methacrylate (MAA-MAN-tBMA) copolymers. The suspension polymerization was stabilized by reducing the solubility of MAA by the salting-out effect and replacing formamide (a common PMI foaming agent) with tBMA.

Effect of Patient Positioning on CT Number Accuracy: A Phantom Study Comparing Energy Integrating and Deep Silicon Photon Counting Detector CT.

Objective: Patient positioning during clinical practice can be challenging, and mispositioning leads to a change in CT number. CT number fluctuation was assessed in single-energy (SE) EID, dual-energy (DE) EID, and deep silicon photon-counting detector (PCD) CT over water-equivalent diameter (WED) with different mispositions.

Methods: A phantom containing five clinically relevant inserts (Mercury Phantom, Gammex) was scanned on a clinical EID CT and a deep silicon PCD CT prototype at vertical positions of 0, 4, 8, and 12 cm.

V6 encoded by mulberry crinkle leaf virus is important for viral DNA replication.

Mulberry crinkle leaf virus (MCLV) is a representative species of the genus Mulcrilevirus in the family Geminiviridae. Here, we identified an additional V6 ORF which embedded within the V4 ORF in the MCLV virion-sense strand. The expression of V6 was confirmed by analyzing the promoter activity of V6 ORF upstream sequences and quantifying the viral DNA accumulation in V6-mutant MCLV-infected tomato plants.