Corrigendum to "Selenium enhancement strategy under precise fertilization in foxtail millet rhizosphere" [Heliyon Volume , Issue 11, 15 June 2024, e32764].

[This corrects the article DOI: 10.1016/j.heliyon.

TRIOL attenuates intracerebral hemorrhage injury by bidirectionally modulating microglia- and neuron-mediated hematoma clearance.

Intracerebral hemorrhage (ICH) represents the most severe subtype of stroke, and the lack of effective clinical pharmacotherapies poses a substantial threat to human health. Hematoma plays a crucial role in determining the prognosis of ICH patients by causing primary mechanical extrusion, followed by secondary brain injuries, such as cerebral edema, iron-mediated oxidative stress, and inflammation resulting from its degradation products. 5α-androst-3β,5α,6β-triol (TRIOL) is a neuroprotective steroid currently undergoing phase II clinical trial for acute ischemic stroke with anti-oxidative and anti-inflammatory properties.

Biodynamic Modeling and Analysis of Human-Exoskeleton Interactions in Simulated Patient Handling Tasks.

Objective: To investigate the biodynamics of human-exoskeleton interactions during patient handling tasks using a subject-specific modeling approach.

Background: Exoskeleton technology holds promise for mitigating musculoskeletal disorders caused by manual handling and most alarmingly by patient handling jobs. A deeper, more unified understanding of the biomechanical effects of exoskeleton use calls for advanced subject-specific models of complex, dynamic human-exoskeleton interactions.

A Flexible Yet Robust 3D-Hybrid Gel Solid-State Electrolyte Based on Metal-Organic Frameworks for Rechargeable Lithium Metal Batteries.

Compared to traditional liquid electrolytes, solid electrolytes have received widespread attention due to their higher safety. In this work, a vinyl functionalized metal-organic framework porous material (MIL-101(Cr)-NH-Met, noted as MCN-M) is synthesized by postsynthetic modification. A novel three-dimensional hybrid gel composite solid electrolyte (GCSE-P/MCN-M) is successfully prepared via in situ gel reaction of a mixture containing multifunctional hybrid crosslinker (MCN-M), lithium bis(trifluoromethanesulfonyl)imide (LiTFSI), ethylene carbonate (EC), diethylene glycol monomethyl ether methacrylate (EGM) and polyethylene (vinylidene fluoridee) (PVDF).

Development and evaluation of a clinical nursing decision support system for the prevention of neonatal hypoglycaemia.

Background: Hypoglycaemia is one of the most common complications during the neonatal period. Recurrent hypoglycaemia episodes can result in neurodevelopmental deficits and even sudden death. Available evidence indicates that healthcare professionals ought to promptly assess the risk of hypoglycaemia in newborns immediately following birth and formulate the most suitable preventive strategies.

NAT10 Modulates Atherosclerosis Progression Mediated by Macrophage Polarization Through Regulating ac4C Modification of TLR9.

Atherosclerosis (AS) is an inflammatory disease affected by macrophage polarization. N-acetylcytosine (ac4C) modification mediated by N-acetyltransferase 10 (NAT10). In this study, we aimed to elucidate the role of ac4C modification mediated macrophage polarization in AS through in vivo and in vitro experiments.

2-Hydroxyisobutyric acid targeted binding to MT-ND3 boosts mitochondrial respiratory chain homeostasis in hippocampus to rescue diabetic cognitive impairment.

Background: The prevalence of diabetic cognitive impairment (DCI) is significant, some studies have shown that it is related to mitochondrial respiratory chain homeostasis, but the specific mechanism is not clear. 2-hydroxyisobutyric acid (2-HIBA) is a novel short-chain fatty acid with potential applications in the treatment of metabolic diseases because it can regulate mitochondrial disorders. Our aim was to explore a novel mechanism of action for 2-HIBA in the treatment of DCI in mitochondrial respiratory chain homeostasis.

The influence of parents' oral health literacy and behavior on oral health of preschool children aged 3-6 years- evidence from China.

Background: Direct and indirect associations have been identified among health literacy, health behavior, and health status. Thus, we aimed to investigate the influence of oral health literacy and behaviors in parents on their children's oral health status. Moreover, we aimed to analyze the mentioned mediating effects through oral health behavior management.

Matrine regulates autophagy in ileal epithelial cells in a porcine circovirus type 2-infected murine model.

Introduction: Porcine circovirus type 2 (PCV2) is an important pathogen that causes diarrhea in nursery and fattening pigs, resulting in huge economic losses for commercial pig farms. Protective efficacy of vaccines is compromised by mutations in pathogens. There is an urgent need to articulate the mechanism by which PCV2 destroys the host's intestinal mucosal barrier and to find effective therapeutic drugs.

Spatiotemporal dynamic assessment and obstacle analysis of economic resilience in China's marine fisheries.

With global climate change and increased overfishing, the sustainable development of marine fisheries economies faces many challenges. This study evaluates the resilience of the marine fishery system in China's coastal areas in a systematic, scientific, and comprehensive manner by establishing the ANP-EWM-TOPSIS comprehensive evaluation system, analyzing the temporal and spatial changes in the economic resilience of marine fisheries, and exploring the main obstacles affecting resilience. The results show that the fishery system in Chinese marine regions demonstrates significant resilience both temporally and spatially.

Black shale high geological background potential toxic elements(PTEs) in middle reaches of the Yangtze River tributary basin water environment, China: Distribution, pollution sources, and risk assessment.

As a typical high geological background area in the middle reaches of the Yangtze River tributary basin in China, the Loushao Basin in Hunan is covered with high mineral black shale, with an average element value 4.76-8.97 times higher than the world average rock level.

Reactivities of tertiary phosphines towards allenic, acetylenic, and vinylic Michael acceptors.

The addition of phosphines (PR) to Michael acceptors is a key step in many Lewis-base catalysed reactions. The kinetics of the reactions of ten phosphines with ethyl acrylate, ethyl allenoate, ethyl propiolate, ethenesulfonyl fluoride, and ethyl 2-butynoate in dichloromethane at 20 °C was followed by photometric and NMR spectroscopic methods. The experimentally determined second-order rate constants show that electronic effects in sterically unencumbered phosphines affect their nucleophilicity towards different classes of Michael acceptors in the same ordering.

Substrate-Controlled [8 + 3] Cycloaddition of Tropsulfimides and Tropones with Zwitterionic Allenyl Palladium Species Derived from Vinylidenecyclopropane-diesters.

A palladium-catalyzed regioselective [8 + 3] cycloaddition of tropsulfimides and tropones with vinylidenecyclopropane-diesters (VDCP-diesters) has been disclosed in this paper, affording decahydro-1-cyclohepta[]pyridine derivatives bearing an allene moiety or decahydro-1-cyclohepta[]pyran derivatives having a conjugated diene unit in moderate to good yields. The reactions proceed through a zwitterionic allenyl palladium species derived from VDCP-diesters. The substrate scopes have been investigated and the plausible reaction mechanisms have also been proposed according to the previous work, the first captured zwitterionic Pd-allenyl intermediate, and control experiments.

Impact of the COVID-19 pandemic on patients with peripheral arterial disease in China: a multicenter cross-sectional study.

This study aims to understand the repercussions of the COVID-19 pandemic on hospitalized patients with peripheral arterial disease (PAD) in China, who did not contract SARS-CoV-2. We conducted a multicenter cross-sectional analysis comparing the characteristics and outcomes of hospitalized PAD patients across two distinct periods: Pre-pandemic (P1, from January 2018 to December 2019) and during the pandemic (P2, from January 2020 to December 2021). During P1, 762 hospitalized patients were treated, with an average age of 72.

Research of multi-label text classification based on label attention and correlation networks.

Multi-Label Text Classification (MLTC) is a crucial task in natural language processing. Compared to single-label text classification, MLTC is more challenging due to its vast collection of labels which include extracting local semantic information, learning label correlations, and solving label data imbalance problems. This paper proposes a model of Label Attention and Correlation Networks (LACN) to address the challenges of classifying multi-label text and enhance classification performance.

Baicalin Inhibits FIPV Infection In Vitro by Modulating the PI3K-AKT Pathway and Apoptosis Pathway.

Feline infectious peritonitis (FIP), a serious infectious disease in cats, has become a challenging problem for pet owners and the industry due to the lack of effective vaccinations and medications for prevention and treatment. Currently, most natural compounds have been proven to have good antiviral activity. Hence, it is essential to develop efficacious novel natural compounds that inhibit FIPV infection.

Concentration-QTc analysis of soticlestat in healthy adults: An alternative to a thorough QT study.

Aim: This study aimed to examine the cardiac and overall safety and pharmacokinetic (PK) profiles of soticlestat (TAK-935), an oral, first-in-class selective cholesterol 24-hydroxylase inhibitor.

Methods: Data came from a randomised, phase 1 study of soticlestat in 33 healthy Japanese adults (NCT04461483); 24 adults in Part 1 (single-dose soticlestat 200-1200 mg or placebo) and 9 in Part 2 (soticlestat 100-300 mg twice daily or placebo for 21 days). PK sample collection was paired with 12-lead electrocardiogram data from continuous Holter recordings.

Microbiological and clinical effects of probiotic-related Zeger therapy on gingival health: a randomized controlled clinical trial.

Background: This single-blind randomized controlled trial was aimed to evaluate the microbiological and clinical effects of Zeger therapy on gingival health.

Methods: Twenty-four adults with gingivitis were recruited and monitored micro-biologically and clinically at baseline (Day 0), 4 weeks (Day 29) after therapy. All volunteers received one-stage full-mouth supragingival scaling as basic oral health care for baseline, and then randomly divided into experimental (koumiss, n = 12) or control (none, n = 12) group.

The Synergistic Inhibitory Effect of Combination Drug Treatment of Enteromorpha Prolifera Polysaccaharide and Doxorubicin Hydrochloride on A549 Cell.

Background: As a common drug for tumor therapy, doxorubicin hydrochloride (DOX) is not yet widely used as a clinical solution. This is due to its toxicity and potential drug resistance.

Objective: This study investigated the inhibitory effect of enteromorpha prolifera polysaccaharide (EPP) combined with doxorubicin hydrochloride (DOX) on A549 cells, which fall into the cell line of human non-small cell lung cancer (NSCLC).

Determining Individualized Foot Progression Angle for Reduction of Knee Medial Compartment Loading during Stepping.

Purpose: Modifying foot progression angle (FPA), the angle between the line from the heel to the second metatarsal head and the line of progression, can reduce peak knee adduction moment (pKAM). However, determining the optimal FPA that minimizes pKAM without inducing unnatural walking patterns can be challenging. This study investigated the FPA-pKAM relationship using a robotic stepping trainer to assess the feasibility of determining the optimal FPA based on this relationship.

Transport Pathways of Nitrate in Stormwater Runoff Inferred from High-Frequency Sampling and Stable Water Isotopes.

Storm events can mobilize nitrogen species from landscapes into streams, exacerbating eutrophication and threatening aquatic ecosystems as well as human health. However, the transport pathways and storm responses of different nitrogen forms remain elusive. We used high-frequency chemical and isotopic sampling to partition sources of stormwater runoff and determine transport pathways of multiple nitrogen forms in an agricultural catchment.