Alternating electrodeposition fabrication of graphene-buffered nickel-cobalt layered double hydroxide supercapacitor electrodes with superior rate capability.

Combining pseudocapacitive materials with carbon materials, such as graphene, is a promising strategy to enhance their performance. In this study, we present a novel and feasible approach involving the alternating electrodeposition of reduced graphene oxide (rGO) and nickel-cobalt layered double hydroxide (NiCo-LDH) onto carbon cloth (CC) current collectors to fabricate binder-free supercapacitor electrodes with a layered LDH/rGO/LDH/rGO/CC architecture. The rGO layers are not only coated on CC substrate to regulate the electrodeposition of LDH nanosheets, but also interposed between the LDH layers to further enhance conductivity and provide buffering effects.

A Study on the Electrochemical Performance of SLMed Al6061/TiB2 Composite Anodes Caused by Laser Power.

Aluminum-air batteries have attracted more attention in recent years due to the theoretical possibility of replacing lithium batteries. Al6061/0.5wt.

27-Hydroxymangiferolic Acid Extends Lifespan and Improves Neurodegeneration in by Activating Nuclear Receptors.

27-Hydroxymangiferolic acid (27-HMA) is a naturally occurring compound in mango fruits that exhibits diverse biological functions. Here, we show that 27-HMA activates the transcriptional activity of farnesoid X receptor (FXR), a nuclear receptor transcription factor, extending the lifespan and healthspan in (). Meanwhile, the longevity-promoting effect of 27-HMA was attenuated in the mutants of and the FXR homologs, indicating that the longevity effects of 27-HMA in may depend on nuclear hormone receptors (NHRs).

The ARC neurons play a crucial role in the regulation of energy homeostasis.

Recent single-cell RNA sequencing study suggested that CRABP1 expressing neurons in the arcuate nucleus (ARC neurons) were a distinct group of neurons. However, the physiological role of ARC neurons remains unexplored. Here, we demonstrated that ARC neurons played a crucial role in regulation of energy homeostasis in male mice.

Economic impact of chicken diseases and other causes of morbidity or mortality in backyard farms in low-income and middle-income countries: a systematic review and meta-analysis.

Background: Backyard chicken farming is usually subsistence and predominates in low-income countries and, to a lesser extent, in middle-income countries. Chicken flocks are generally raised by households in a low-input, low-output system in contact with other flocks, livestock, and wildlife. This low biosecurity setting predisposes chickens to diseases and injuries.

Quantum Monte Carlo and Density Functional Theory Study of Strain and Magnetism in 2D 1T-VSe with Charge Density Wave States.

Two-dimensional (2D) 1T-VSe has prompted significant interest due to the discrepancies regarding alleged ferromagnetism (FM) at room temperature, charge density wave (CDW) states, and the interplay between the two. We employed a combined Diffusion Monte Carlo (DMC) and density functional theory (DFT) approach to accurately investigate the magnetic properties, CDW states, and their responses to strain in monolayer 1T-VSe. Our calculations show the delicate competition between various phases, revealing critical insights into the relationship between their energetic and structural properties.

Atomic Engineering and Aggregation Effect to Regulate Synergistically Type I Reactive Oxygen Species of AIE-Active Deep Red/Near Infrared Red Photosensitizer.

"Molecular science" has long been regarded as the golden rule to guide the design of organic materials' performances in the past many years, but some interesting phenomena of conventional aggregation-caused fluorescence quenching and new aggregation-induced emission reflect that materials' properties would be changed from "molecule" to "aggregate". Therefore, "molecular science" theory faces certain limitations to guide regulating the performance of materials at aggregation. In this work, it is discovered that the photosensitizer's performances contain fluorescence and reactive oxygen species, which could be affected by changing molecular atoms and aggregation form.

Flower-like MoS-Induced α-FeO/Fe(MoO) Nanocomposite as an Ultrafast Sensor for Ethanol Detection.

An ultrafast-responsive α-FeO/Fe(MoO) nanocomposite was developed for the detection of ethanol vapor. The α-FeO/Fe(MoO) nanocomposite was synthesized utilizing a green, normal-pressure, microwave-assisted method followed by an in situ solid-state reaction process with flower-like MoS as a unique precursor. The resulting α-FeO/Fe(MoO) composite presents a porous, agminated petal-like structure with α-FeO nanoparticles homogeneously attached to the surfaces of Fe(MoO) nanosheets.

Involvement of the AVP/OT system and lateral septum in the modulation of anxiety/depression caused by 14-week and 20-week social isolation.

Introduction: Chronic social isolation (CSI) stress leads to numerous maladaptive changes in physiology and psychology, however, very little is known about the effects of longer time-scale CSI and there are divergent views regarding the underlying mechanisms. This study aimed to elucidate the common neuroendocrine mechanisms underlying the maladaptive changes caused by 14-week (14wk-) and 20-week (20wk-) CSI.

Methods: We investigated the impacts of 14wk- and 20wk- CSI on anxiety/depression-like behaviors in male C57BL/6N mice with classical behavioral tests, and the immunofluorescence method was used for quantification of the arginine vasopressin (AVP)/Oxytocin (OT) positive neurons in the PVN and screening out the differential activation brain regions (DABrs) on exposure of tail suspension.

A multicenter prospective clinical trial reveals cell free DNA methylation markers for early esophageal cancer.

Background: Current methods for detecting esophageal cancer (EC) are generally invasive or exhibit limited sensitivity and specificity, especially for the identification of early-stage tumors.

Methods: We identified potential methylated DNA markers (MDM) from multiple genomic regions in a discovery cohort and a diagnostic model was developed and verified in a model-verification cohort of 297 participants. The accuracy of the MDM panel was validated in a multicenter, prospective cohort (n = 1429).

Augmented reality guided versus computed tomography guided percutaneous lung nodule localization: a noninferiority randomized clinical trial.

Hypothesis: This study hypothesized that augmented reality (AR) technology has comparable accuracy and safety to conventional CT localization in guiding percutaneous transthoracic lung puncture (PTLP) to localize small pulmonary nodules.

Methods: This study was a prospective, non-inferiority randomized clinical trial. Patients were randomly assigned between 23 May 2023, and 26 September 2023.

Youth Who Control HIV on Antiretroviral Therapy Display Unique Plasma Biomarkers and Cellular Transcriptome Profiles Including DNA Repair and RNA Processing.

Combination antiretroviral therapy (ART) suppresses detectible HIV-1 replication, but latent reservoirs and persistent immune activation contribute to residual viral-associated morbidities and potential viral reactivation. youth with HIV (YWH) virally suppressed on ART early in infection before CD4 T cell decline with fewer comorbidities compared to adults represent a critical population for identifying markers associated with viral control and predictors of viral breakthrough. This study employed a multi-omics approach to evaluate plasma biomarkers and cellular gene expression profiles in 52 participants, including 27 YWH on ART for 144 weeks and 25 youth with no infection (NI) (ages 18-24).

Superior electron transport in the single-crystalline TiCoSb-based half-Heuslers.

Half-Heuslers emerged as promising candidates for medium- and high-temperature thermoelectric power generation. However, polycrystalline half-Heuslers inevitably suffer from the defect-dominated scattering of electrons that greatly limits the optimization of their electronic properties. Herein, high-quality TiCoSb-based single-crystals with a dimension above 1 cm have been obtained.

Development and validation of the systemic nutrition/inflammation index for improving perioperative management of non-small cell lung cancer.

Background: Systemic nutrition and inflammation status is recognized for its influence on cancer survival, yet its role in perioperative outcomes remains poorly defined. This study aimed to refine the assessment of systemic nutrition and inflammation status in non-small cell lung cancer (NSCLC) patients and to elucidate its impact on perioperative outcomes.

Methods: All patients underwent video-assisted thoracoscopic lobectomy, with their nutrition and inflammation status assessed based on preoperative blood tests.

A pelvis MR transformer-based deep learning model for predicting lung metastases risk in patients with rectal cancer.

Objective: Accurate preoperative evaluation of rectal cancer lung metastases (RCLM) is critical for implementing precise medicine. While artificial intelligence (AI) methods have been successful in detecting liver and lymph node metastases using magnetic resonance (MR) images, research on lung metastases is still limited. Utilizing MR images to classify RCLM could potentially reduce ionizing radiation exposure and the costs associated with chest CT in patients without metastases.

Reconstruction of multiple volar finger defects with a single-pedicle five-lobed free SCIP flap: a case report of two patients.

Background: The management of extensive volar soft tissue defects in multiple fingers remains challenging for plastic surgeons. To date, although various types of flaps have been developed as reconstruction options, the applications remain limited by the shortcomings of bloated appearance, insufficient flap area, prolonged treatment time, persistent donor complications, and the sharply increased surgical complexity with the increased number of injured fingers. The superficial circumflex iliac artery perforator (SCIP) flap avoids the shortcomings of conventional flaps whilst allowing harvesting as a single-pedicle multiple-lobed form, rendering it the standout first-tier flap procedure in the repair of multiple soft tissue defects.

Generation and characterization of a pluripotent stem cell line CIPi005-A derived from a female patient carrying non-canonical splice site c.827Â +Â 1G > A in WDR45.

β-propeller protein-associated neurodegeneration (BPAN) is a rare neurodegenerative disease with developmental retardation, epilepsy and extrapyramidal symptoms, associated with mutations in WDR45. In this article, we generated an iPSC line from peripheral blood mononuclear cells (PBMCs) of a 3-year-old girl who carries a splice site mutation c.827 + 1G > A in WDR45.

Circulating fatty acid profiles impact total, cardiovascular disease, and cancer mortality in a population-based prospective cohort study.

Background: Evidence linking circulating fatty acids (FAs) to mortality from age-related chronic diseases was limited and inconsistent. We aimed to investigate the associations of plasma FAs with total, cardiovascular disease (CVD), and cancer mortality and explore the potential mechanism.

Methods: 117,871 individuals were prospectively followed in the UK Biobank.

Geniposide Inhibits Non-Small Cell Lung Cancer by Regulating Proliferation, Apoptosis, Invasion, Migration, Epithelial-Mesenchymal Transition, and Cancer Stem-Like Cell Property Via Wnt/β-Catenin Pathway.

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. Geniposide, an active compound of Gardeniae Fructus, has antithrombotic, antitumor, neuroprotective, hepatoprotective, cholestatic, and other effects. The present study aimed to investigate the effects of geniposide on NSCLC cells, as well as its underlying mechanism.

Dynamic functional connectivity patterns predict early antidepressant treatment response in drug-naïve, first-episode adolescent MDD.

Objective: Adolescents with major depressive disorder (MDD) exhibit abnormal dynamic functional connectivity (dFC) patterns, but it remains unclear whether these aberrant dFC patterns are linked to antidepressant treatment. The aim of this study is to investigate whether dFC patterns will be changed by antidepressant treatment, as well as whether baseline dFC pattern could predict treatment response in adolescent MDD patients.

Method: We included 35 drug-naïve, first-episode MDD adolescents (age 14.

A shark-derived broadly neutralizing nanobody targeting a highly conserved epitope on the S2 domain of sarbecoviruses.

The continuously evolving Omicron subvariants has diminished the effectiveness of almost all RBD-targeted antibodies in neutralizing these subvariants. The development of broad-spectrum neutralizing antibodies is desired for addressing both current and future variants. Here, we identified a shark-derived nanobody, 79C11, that can neutralize all Omicron subvariants tested so far, including BA.

The prevalence and association of traditional bullying and cyber bullying with mental health among adolescent and youth students in China: a study after the lifting of COVID-19 restrictions.

Background: Although bullying may affect students' mental health, its prevalence and impact on mental health among students in China after the lifting of COVID-19 restrictions remains unclear. This study aimed to explored the prevalence and association of traditional and cyber bullying with mental health among Chinese adolescent and youth students post-COVID-19 restrictions.

Methods: An online survey included 82,873 students from various educational levels in Sichuan Province, China, assessing traditional and cyber victimization, cyber perpetration, COVID-19 experiences, insomnia, anxiety, depression, and post-traumatic stress disorder (PTSD).

Machine Learning in Predicting the Cognitive Improvement of Ventriculoperitoneal Shunt for Chronic Normal Pressure Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage.

Background: Chronic normal pressure hydrocephalus (CNPH) is a recognized sequela of aneurysmal subarachnoid hemorrhage (ASAH). Ventriculoperitoneal shunt (VPS) is a conventional treatment for hydrocephalus, though its effectiveness for CNPH post-ASAH remains unclear.

Methods: We included ASAH patients with CNPH who underwent VPS surgery.

Pathogenetic development, diagnosis and clinical therapeutic approaches for liver metastasis from colorectal cancer (Review).

Colorectal cancer (CRC) is a prevalent malignancy and a significant proportion of patients with CRC develop liver metastasis (CRLM), which is a major contributor to CRC‑related mortality. The present review aimed to comprehensively examine the pathogenetic development and diagnosis of CRLM and the clinical therapeutic approaches for treatment of this disease. The molecular mechanisms underlying CRLM were discussed, including the role of the tumour microenvironment and epithelial‑mesenchymal transition.

sp. nov., a methanogen isolated from potential methane hydrate bearing area offshore southwestern Taiwan.

A novel mesophilic, hydrogenotrophic methanogen, strain CWC-01, was isolated from the sediment sample of the piston core collected at station 3 at Good Weather Ridge area offshore southwestern Taiwan from ORI-902A cruise in 2009. Cells of strain CWC-01 are rod-shaped, measuring 0.4-0.