Increased annexin A2 and decreased β-catenin in adenomyosis contribute to adenomyosis-associated dysmenorrhea.

Objective: To investigate the expression of annexin A2 (ANXA2) and β-catenin in eutopic and ectopic endometrium, and their relationships with adenomyosis-associated dysmenorrhea.

Methods: From December 2013 to June 2014, ectopic endometrium (n=30) and eutopic endometrium (n=30) of adenomyosis were collected as experimental group, and endometrium (n=30) of uterine myoma as control group from the department of gynecology and obstetrics, the affiliated hospital of Inner Mongolia medical university. The expression of ANXA2 and β-catenin was detected by immunohistochemical S-P method, followed by the Pearson correlations for the correlation analysis of ANXA2 and β-catenin with adenomyosis-associated dysmenorrhea.