Polyethyleneimine-assisted one-pot synthesis of Au nanodendrites on carbon nanotube sheet as an efficient SERS substrate.

A polyethyleneimine (PEI)-assisted simple and efficient one-pot hydrothermal reduction method is reported to prepare high-quality gold nanodendrites (AuNDs) on a carbon nanotube (CNT) sheet. We observed that the prepared AuNDs have a well-defined backbone-multiple branching structure. With the systematical investigation of the growth mechanism, it was found that the bromide (Br) ion concentration has an essential effect on the formation of AuNDs.

Effectiveness of high-intensity focused ultrasound combined with gonadotropin-releasing hormone agonist or combined with levonorgestrel-releasing intrauterine system for adenomyosis: A systematic review and meta-analysis.

Gonadotropin-Releasing Hormone Agonist (GnRH-a) and levonorgestrel releasing intrauterine system (LNG-IUS) are conventional conservative treatments for adenomyosis, and high-intensity focused ultrasound (HIFU) is a novel ablation technique. This study aimed to investigate the effectiveness of HIFU combined with GnRH-a or LNG-IUS for adenomyosis patients. In this systematic review and meta-analysis, Pubmed, Embase, Cochrane Library and Scopus databases were searched up to December 2021.

Vigour testing for the rice seed with computer vision-based techniques.

Rice is the staple food for approximately half of the world's population. Seed vigour has a crucial impact on the yield, which can be evaluated by germination rate, vigor index and . Existing seed vigour testing methods heavily rely on manual inspections that are destructive, time-consuming, and labor-intensive.

Differential effects of subchronic acrylonitrile exposure on hydrogen sulfide levels in rat blood, brain, and liver.

Background: Hydrogen sulfide (HS), as the third gasotransmitter participates in both cellular physiological and pathological processes, including chemical-induced injuries. We recently reported acute acrylonitrile (AN) treatment inhibited endogenous HS biosynthesis pathway in rat and astrocyte models. However, there is still no evidence to address the correlation between endogenous HS and sub-chronic AN exposure.

High-grade endometrial stromal sarcoma in cesarean section scar isthmocele - case report.

Objective: Cesarean section scar defect isthmocele, the pouchlike defect in the anterior uterine wall of the prior cesarean site. No previous report of malignant neoplasm in the isthmocele have been published. We reported a case of High-grade endometrial stromal sarcoma in isthmocele.

Acute acrylonitrile exposure inhibits endogenous HS biosynthesis in rat brain and liver: The role of CBS/3-MPST-HS pathway in its astrocytic toxicity.

Hydrogen sulfide (HS) as the third gasotransmitter molecule serves various biological regulatory roles in health and disease. Acrylonitrile (AN) is a common occupational toxicant and environmental pollutant, causing brain and liver damage in mammals. The biotransformation of AN is dependent-upon reduced glutathione (GSH), cysteine and other sulfur-containing compounds.

Lensfree Diffraction Reconstruction Approach Enables Early Detection of Cancer In Vitro Based on Molecular Diagnosis.

Before there are any megascopic cancer clinical symptoms, molecular diagnosis is the main method for detecting cancer-associated gene and tumor marker. The existing detection facilities are all expensive, complicated to operate, and time-consuming, thereby making them difficult to popularize and benefit humans. In this study, we proposed a high-throughput and cost-effective approach, which enables accurate detection of extremely rare cancer cells based on molecular diagnosis of target tumor marker and a lensfree diffraction imaging platform.

Differential susceptibility of PC12 and BRL cells and the regulatory role of HIF-1α signaling pathway in response to acute methylmercury exposure under normoxia.

Hypoxia-inducible factor 1 (HIF-1) is a critical nuclear transcription factor for adaptation to hypoxia; its regulatable subunit, HIF-1α, is a cytoprotective regulatory factor. We examined the effects of methylmercury (MeHg) in rat adrenal pheochromocytoma (PC12) cells and the rat hepatocyte cell line BRL. MeHg treatment led to time- and concentration-dependent toxicity in both lines with statistically significant cytotoxic effects at 5 μM and 10 μM in PC12 and BRL, respectively, at 0.

Acute Methylmercury Exposure and the Hypoxia-Inducible Signaling Pathway under Normoxic Conditions in the Rat Brain and Astrocytes .

Background: As a ubiquitous environmental pollutant, methylmercury (MeHg) induces toxic effects in the nervous system, one of its main targets. However, the exact mechanisms of its neurotoxicity have not been fully elucidated. Hypoxia-inducible (), a transcription factor, plays a crucial role in adaptive and cytoprotective responses in cells and is involved in cell survival, proliferation, apoptosis, inflammation, angiogenesis, glucose metabolism, erythropoiesis, and other physiological activities.

Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ.

Methylmercury (MeHg) is a ubiquitous environmental toxicant that leads to long-lasting neurological deficits in animals and humans. Curcumin, a polyphenol obtained from the rhizome of turmeric, has well-known antioxidant functions. Here, we evaluated curcumin's efficacy in mitigating MeHg-induced cytotoxicity and further investigated the underlying mechanism of this neuroprotection in primary rat astrocytes.

Activation of autophagic flux and the Nrf2/ARE signaling pathway by hydrogen sulfide protects against acrylonitrile-induced neurotoxicity in primary rat astrocytes.

Hydrogen sulfide (HS), the third gasotransmitter, has been shown to act as a neuroprotective factor in numerous pathological processes; however, its underlying mechanism(s) of action remain unclear. It is widely accepted that activation of moderate autophagy and the Nrf2/ARE signaling pathway play important roles in the biological self-defense systems. In the present study, we investigated whether exogenous HS protects against the cytotoxicity of acrylonitrile (AN), a neurotoxin, in primary rat astrocytes.

An approach for cell viability online detection based on the characteristics of lensfree cell diffraction fingerprint.

To overcome the drawbacks such as low automation and high cost, an approach for cell viability online detection is proposed, based on the extracted lensfree cell diffraction fingerprint characteristics. The cell fingerprints are acquired by a constructed large field-of-view (FOV) diffraction imaging platform without any lenses. The approach realizes distinguishing live and dead cells online and calculating cell viability index based on the number of live cells.

Molecular genetic characterization of a prenatally detected de novo interstitial deletion of chromosome 20p (20p12-p13) encompassing JAG1 and a literature review of prenatal diagnosis of Alagille syndrome.

Objective: We present prenatal diagnosis and molecular genetic characterization of a de novo interstitial deletion of chromosome 20p (20p12-p13) and a literature review of prenatal diagnosis of Alagille syndrome (ALGS).

Case Report: A 33-year-old woman underwent amniocentesis at 17 weeks of gestation because of an abnormal result of combined first-trimester screening. Her husband was 35 years old, and there was no family history of congenital malformations.

Preconditioning of endoplasmic reticulum stress protects against acrylonitrile-induced cytotoxicity in primary rat astrocytes: The role of autophagy.

This study explored the protective effects of endoplasmic reticulum (ER) stress preconditioning induced by 2-deoxy-d-glucose (2-DG) or oxidized dithiothreitol (DTTox) on acrylonitrile (AN)-induced cytotocity in primary rat astrocytes. Cells were pretreated with 2-DG or DTTox for different times at various concentration. Next, astrocytes were treated with 2.

Differential protection of pre- versus post-treatment with curcumin, Trolox, and N-acetylcysteine against acrylonitrile-induced cytotoxicity in primary rat astrocytes.

Objective: This study was designed to examine the differential protection of pre- versus post-treatment with three different antioxidants, curcumin (CUR), Trolox, and N-acetylcysteine (NAC), on acrylonitrile (AN)-induced cytotoxicity in primary rat astrocytes.

Methods: Primary astrocyte cultures were treated with CUR, Trolox and NAC for 4h prior to, or following 24h treatment with AN (2.5mM).

Pregnancy after hysteroscopic endometrial ablation without endometrial preparation: a report of five cases and a literature review.

Objective: Treating menorrhagia in women of reproductive age by endometrial ablation (EA) decreases menstrual flow and increases quality of life. However, unexpected pregnancy and associated complications are challenges following EA.

Materials And Methods: From January 2000 to March 2008, a total of 356 women aged 26-45 years with persistent menorrhagia underwent total hysteroresectoscopic EA with follow-up at our hospital and were retrospectively evaluated.

A 51-month follow-up of fresh autologous hemi-ovary transplantation at the pfannenstiel incision site after hysterectomy and accidental bilateral salpingo-oophorectomy in a premenopausal woman.

Objective: This case report evaluates a 51-month follow-up of the hormonal profiles and the menopausal status after fresh autologous hemi-ovary transplantation to the Pfannenstiel incision site in a woman aged 32 years after a total hysterectomy and accidental bilateral salpingo-oophorectomy.

Case Report: A 32-year-old, unmarried woman without sexual experience had undergone a total hysterectomy and accidental bilateral salpingo-oophorectomy for huge uterine fibroids and dense pelvic adhesion. A fresh autologous right normal hemi-ovary was transplanted into the adipose tissue on the right side of the Pfannenstiel incision site.

Predicted value of renin activity in a woman who had severe ovarian hyperstimulation syndrome with internal jugular vein thrombosis.

Objective: To assess plasma renin activity in a patient with severe ovarian hyperstimulation syndrome (OHSS) and internal jugular vein thrombosis.

Design: Case report.

Setting: University-affiliated infertility center.

Continuous abdominal paracentesis for management of late type severe ovarian hyperstimulation syndrome.

The ovarian hyperstimulation syndrome (OHSS) is often observed in patients undergoing assisted reproductive technology (ART). In severe form OHSS is a serious and potentially life-threatening. Here we report a 36-year-old woman with primary infertility due to endometriosis who underwent controlled ovarian hyperstimulation.

A useful technique for the control of severe cesarean hemorrhage: report of three cases.

When we are confronted with a patient experiencing placenta previa with massive hemorrhage in cesarean delivery, hemostasis is first attempted using uterotonic drugs, uterine massage, and intrauterine packing. However, if these maneuvers fail, then uterine artery ligation, whole myometrial suture, and subendometrial vasopressin injection should be attempted. Perhaps these procedures alone or in combination can successfully control the hemorrhage.