Background: One anastomosis gastric bypass (OAGB) is recognized as a standard procedure in metabolic surgery. However, concerns about postoperative bile reflux and nutritional risks are prevalent. Comparatively, sleeve gastrectomy with loop duodenojejunal bypass (SG + LoopDJB) bypasses an equivalent length of the foregut as OAGB while maintaining pyloric function.
View Article and Find Full Text PDFMajor BMS are modified through loop rather than Roux-en-Y type reconstruction recently, and this study systematically reviews the BMS from the perspective of SA (single anastomosis) and DA (double anastomosis) procedures, aiming to research the differences among bariatric procedures. A total of 39 studies compared SA- and DA-BMS were finally eligible for analysis after searching in PubMed, Web of Science, and Cochrane Library. Compared with DA, SA shortens operative time and decreases complications especially obstruction, internal hernia, and reoperation.
View Article and Find Full Text PDFObjective: The goal of this study was to compare measures of weight regain (WR) and their association with the glucose metabolism deterioration within 3 years following bariatric surgery among Chinese patients with obesity and type 2 diabetes mellitus (T2DM).
Methods: Among a retrospective cohort of 249 patients with obesity and T2DM who underwent bariatric surgery and were followed up to 3 years, WR was assessed by weight changes, BMI changes, percentage of presurgery weight, percentage of nadir weight, and percentage of maximum weight lost (%MWL). Glucose metabolism deterioration was defined as a change from an absence of antidiabetic medication use to use, or absence of insulin use to use, or an increase in glycated hemoglobin by at least 0.
Here, we studied the metabolic function of LAMTOR1 from macrophages using LAMTOR1 macrophage-specific knockout (MKO) mice. LAMTOR1 MKO mice showed resistance to high-fat diet (HFD)-induced obesity, lipid steatosis, and glucose metabolic disorders, with elevated levels of pro-inflammatory cytokines. The energy expenditure, oxygen consumption, and CO production increased significantly in HFD-fed MKO vs.
View Article and Find Full Text PDFDeveloping highly-efficient multifunctional electrocatalysts for energy conversion devices is of great importance. A sequence of nano-sized bimetal (Al, Cr, Fe) niobium oxide nanoparticles anchored on aloe peel-derived porous carbon skeleton hybrids (AN/APPC, CN/APPC, and FN/APPC) are successfully prepared via co-precipitation avenue and used as electrocatalysts for photovoltaics and alkaline hydrogen evolution reaction. Benefiting from the synergies between nano-sized metal niobium oxides and highly conductive porous carbon skeleton, these robust polycomponent hybrid electrocatalysts exhibit superior catalytic performances for accelerating the triiodide reduction and hydrogen evolution reaction.
View Article and Find Full Text PDFObjective: The aim of this study was to explore the association of 1,5-anhydroglucitol with acute C peptide response (ACPR) to arginine among patients with type 2 diabetes.
Methods: Patients with type 2 diabetes were enrolled from the Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital. ACPR was assessed using arginine stimulation test.
Manganese tungstate (MnWO), zinc tungstate (ZnWO), and copper tungstate (CuWO) embedded biomass-derived carbon (MWO-C, ZWO-C, CWO-C) was synthesized by hydrothermal treatment and investigated as counter electrode (CE) catalysts to test electrochemical activity. Biomass-derived carbon was used as the shape controlling agent, which changed the morphology of MWO from spherical to spindle-like. Owing to the synergistic effect between tungsten-based bimetal oxides and biomass-derived carbon, the MWO-C, ZWO-C, and CWO-C catalysts exhibited enhanced electrochemical performance in dye-sensitized solar cells (DSSCs) system.
View Article and Find Full Text PDFAims: The association between β-cell function and glycemic variability remains to be clarified in insulin-treated patients with type 2 diabetes. Therefore, the study sought to examine the association of various indices of β-cell function with glycemic variability in Chinese insulin-treated patients with type 2 diabetes.
Methods: Glycemic variability was assessed by the coefficient of variation (CV) of glucose levels with the use of continuous glucose monitoring (CGM).