Delayed Administration of IGFBP7 Improved Bone Defect Healing via ZO-1 Dependent Vessel Stabilization.

The vascular response following injury is pivotal for successful bone-defect repair but constitutes a major hurdle in the field of regenerative medicine. Throughout this process, vessel stabilization is crucial to provide an adequate nutrient supply and facilitate efficient waste removal. Therefore, this study investigated whether promoting vascular stabilization improves bone defect repair outcomes.

Comprehensive review of patients with hypercoagulable state in rheumatoid arthritis and strategies to reduce readmission rates: A retrospective cohort study based on protective exploration of traditional Chinese medicine.

This study aimed to investigate the effect of traditional Chinese medicine (TCM) intervention on the risk of readmission and laboratory indicators in patients with rheumatoid arthritis hypercoagulable state. In the retrospective cohort design, patients with RA hospitalized between June 2013 and June 2021 at the First Affiliated Hospital of Anhui University of Chinese Medicine were followed up by telephone. Propensity score matching (PSM) was used to balance deviations in baseline information between patients in the hypercoagulable (HC) and non-hypercoagulable (Non-HC) groups, with exposure defined as receiving TCM treatment for ≥ 1 month.

Red Blood Cell-Related Parameters in Rheumatoid Arthritis: Clinical Value and Immunological Significance.

Rheumatoid arthritis (RA) is characterized by chronic inflammation and autoimmunity. Moreover, the disease activity, co-morbidities, and prognosis of RA are closely associated with changes in red blood cell (RBC)-related parameters. The role of these parameters in RA has therefore been extensively studied.

A new birth weight chart and optimal birth weight percentiles for predicting infant mortality.

Prescriptive BW charts can facilitate discrimination between normal and abnormal birthweight. This study aimed to develop a prescriptive BW chart specific to Asian populations and assess its utility in predicting infant mortality. A retrospective cohort study was conducted using data from Taiwan National Health Insurance Research Database and National Birth Reporting Database.

Multi-scale heterogeneous composite elastomer absorbers synergistically enhanced by CoNi nanospheres and carbon nanotubes.

The advancement of high-performance absorbers is essential for applications in electromagnetic wave absorption (EWA) and stealth technologies. To enhance EWA performances, it is imperative to employ advanced design strategies that incorporate heterogeneous interfaces and multi-scale structures. In this study, we developed a composite elastomer demonstrating exceptional EWA characteristics using a two-step process involving liquid-phase reduction followed by thermal curing.

The prevalence of suboptimal health status among Chinese secondary school students and its relationship with family health: the mediating role of perceived stress and problematic internet use.

Background: The health status of secondary school students has received widespread attention, and family plays an extremely important role in protecting and promoting their health. However, the relationship between family health and suboptimal health status (SHS) among secondary school students and its underlying mechanisms are unclear. This study aims to understand the prevalence of SHS among Chinese secondary school students and analyze the relationship between family health and SHS, and examine the mediating roles of perceived stress and problematic internet use.

Discrepancy in coordination and variation of root and leaf traits among herbaceous and shrub species in the desert, China.

Introduction: Alterations in life forms could simultaneously influence the variability of fine root and leaf traits. However, our understanding of the organ-level coordination and patterns of variation in fine root and leaf traits among desert herbs and shrubs with distinct habits remains limited.

Methods: Consequently, this study examined the leaf and fine root traits of 9 shrubs and 9 herbs across three desert habitats through Sperman's correlation analysis, principal component analysis (PCA), and standardized major axis (SMA) analysis as a means of identifying the hub traits and the resource trade-off strategies employed by desert plants to adapt to their environment.

The efficacy of InterRhythmic care for depression: A randomized control trial.

Objective: This study investigates the efficacy of an InterRhythmic Care (IRC) for major depressive disorder (MDD). There is a lack of clinical studies on its effect on depression.

Methods: In this eight-week, randomized, single-blind, controlled trial, 120 patients with MDD were randomly assigned to receive IRC or Internet general psychoeducation (IGP).

Progress and perspectives of rapid Joule heating for the preparation of highly efficient catalysts.

Functional catalytic materials play an important role in environmental, biological, energy, and other fields, wherein unique properties can be endowed through various synthesis strategies. However, conventional catalyst preparation methods suffer from mild conditions, prolonged treatment and low energy transfer efficiency, thus leading to limited inherent characterisation of catalysts (such as surface oxidation and agglomeration). Recently, the rapid Joule heating method, as a novel synthesis method, has attracted widespread attention owing to its controllable kinetic conditions and eco-friendly operation, while the mechanisms, advantages and recent progress of this method have been summarized in few reviews.

Association of relative fat mass with prevalence of erectile dysfunction in US men: an analysis of NHANES 2001-2004.

The high prevalence of erectile dysfunction (ED) underscores the critical importance of interventions and preventive measures targeting potential risk factors, among which obesity stands out. Relative fat mass (RFM) emerges as a superior indicator for quantifying body fat compared to traditional metrics like body mass index (BMI) or waist circumference (WC). However, research on the relationship between RFM and ED is extremely limited.

Ultra-highly conductive optoelectronic modulated single-molecule nickel bis(dithiolene) junctions with strong molecule-electrode coupling.

Strong molecule-electrode coupling originating from orbit hybridization between gold and the delocalized molecular wires in single-molecule junctions facilitates facile transport towards smart molecular devices. In this paper, we report ultra-highly conductive single-molecule circuits based on highly delocalized nickel bis(dithiolene) (NiS) molecular junctions using scanning tunneling microscope break junction technique. Single-molecule charge transport measurement of both NiS reveals they exhibits high conductance of 10G and 10G, respectively.

The protective effect of higher serum triacylglycerol (51:4) levels against Parkinson's disease.

Emerging evidence has shown a strong correlation between serum triacylglycerol (TAG) levels, the inflammatory response, and Parkinson's disease (PD) onset. However, the causal relationship between TAG levels and PD has not been well-established. We aimed to investigate the relationship between serum TAG levels and risk of PD and explore the potential mediating role of circulating immune cells and inflammatory proteins.

Association between pyrrolizidine alkaloids exposure and risk of abnormal serum indices-Insights from a descriptive cross-sectional study in Yunnan Province.

The hazard of pyrrolizidine alkaloids (PAs) has been widely reported in animal studies but rarely in population-based research, especially reports about daily exposure. A single-centre descriptive cross-sectional study was conducted on 552 Lahu Autonomous County residents recruited in 2021. Blood PAs exposure biomarker (pyrrole- protein adduct, PPA) and serum biochemical indices were measured.

1D/2D Heterostructures: Synthesis and Application in Photodetectors and Sensors.

Two-dimensional (2D) semiconductor components have excellent physical attributes, such as excellent mechanical ductility, high mobility, low dielectric constant, and tunable bandgap, which have attracted much attention to the fields of flexible devices, optoelectronic conversion, and microelectronic devices. Additionally, one-dimensional (1D) semiconductor materials with unique physical attributes, such as high surface area and mechanical potency, show great potential in many applications. However, isolated 1D and 2D materials often do not meet the demand for multifunctionality.

Global burden of zoonotic infectious diseases of poverty, 1990-2021.

Background: The zoonotic infectious diseases of poverty (zIDPs) are a group of diseases contributing to global poverty, with significant impacts on a substantial population. This study aims to describe the global, regional, and national burden of zIDPs-schistosomiasis, cystic echinococcosis, cysticercosis, and food-borne trematodiases (FBTs)-to support policy making and resource allocation for their control and elimination.

Methods: Data of zIDPs from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 were retrieved from 1990 to 2021.

Targeting right orbitofrontal cortex (OFC) with transcranial direct current stimulation (tDCS) can improve cognitive executive function in a major depressive episode, but not depressive mood: A Double-blind Randomized Controlled Pilot Trial.

Transcranial direct current stimulation (tDCS) has emerged as a potential treatment for major depressive episodes (MDE). This study aimed to evaluate the efficacy of targeting the right orbitofrontal cortex (rOFC) with tDCS in improving depressed mood and cognitive function in patients with depression. A double-blind, randomized sham-controlled trial was conducted in which 70 patients with depression were randomly assigned to receive rOFC-tDCS (n = 24), left dorsolateral prefrontal cortex (lDLPFC) tDCS (n = 23), or SHAM (n = 23).