Publications by authors named "Yimin Lin"

The global burden of respiratory diseases such as influenza, tuberculosis, and viral pneumonia necessitates rapid, accurate diagnostic tools to improve healthcare responses. Current methods, including RT-PCR and chest radiography, face limitations in accuracy, speed, accessibility, and cost-effectiveness, especially in resource-constrained settings, often delaying treatment and increasing transmission. This study introduces an Enhanced Multi-Model Deep Learning (EMDL) approach to address these challenges.

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Background: Cerebral protection strategies in type A aortic dissection (TAAD) surgery are critical yet inconclusive. We propose an integrated cerebral protection protocol. This study aimed to evaluate the effectiveness of this protocol.

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Background: Early prediction of heart failure (HF) after acute myocardial infarction (AMI) is essential for personalized treatment. We aimed to use interpretable machine learning (ML) methods to develop a risk prediction model for HF in AMI patients.

Methods: We retrospectively included patients initially with AMI who received percutaneous coronary intervention (PCI) in our hospital from November 2016 to February 2020.

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Intraoperative bleeding is a common issue in various surgical procedures, and the extent of bleeding significantly impacts the safety, efficacy, and prognosis of surgery. Therefore, accurate assessment of intraoperative blood loss and timely intervention are essential for the smooth progression of surgery and favorable clinical outcomes. Currently, clinical methods for estimating blood loss are generally classified into two main categories: visual and calculation methods.

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Smoking is one of the major contributors to airway injuries. N-acetylcysteine (NAC) has been proposed as a treatment or preventive measure for such injuries. However, the exact nature of the smoking-induced injury and the protective mechanism of NAC are not yet fully understood.

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Article Synopsis
  • The Chinese government and academia are focusing on the ecological restoration of historical abandoned mines, especially in Ganzhou, a key mineral resource city.
  • A new evaluation system is created that uses residents' satisfaction as a key measure, including ecology, economy, and society.
  • The study finds that while ecological benefits are prioritized, residents feel unsatisfied with the social and economic improvements, leading to proposed countermeasures for better ecological restoration efforts.
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  • The promotion of green intelligent buildings (GIBs) is crucial for reducing carbon emissions and environmental pollution, necessitating a well-structured subsidy mechanism.
  • There is a lack of research on dynamic subsidy mechanisms, so this study develops an evolutionary game model to analyze the strategies of local governments and developers under these subsidies.
  • Key findings indicate that a dynamic subsidy mechanism leads to an evolutionarily stable strategy, with the subsidy adjustment rate being the most influential factor for promoting the effective diffusion of GIBs.
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  • Type-2 diabetes mellitus (T2DM) is linked to insulin resistance and insufficient insulin release, and the study investigates the traditional Chinese medicine extract AMK-CCL for its potential therapeutic effects on this condition using a diabetic fly model.
  • The active components of AMK-CCL were analyzed, and various metabolic parameters were measured to assess its impact on glucose regulation and metabolic health in diabetic flies.
  • The results show that AMK-CCL significantly improved insulin sensitivity by enhancing PI3K/Akt signaling, leading to better glucose uptake and metabolic outcomes, indicating its potential for clinical application in treating T2DM.
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Fenton and Fenton-like processes, which could produce highly reactive species to degrade organic contaminants, have been widely used in the field of wastewater treatment. Therein, the chemistry of Fenton process including the nature of active oxidants, the complicated reactions involved, and the behind reason for its strongly pH-dependent performance, is the basis for the application of Fenton and Fenton-like processes in wastewater treatment. Nevertheless, the conflicting views still exist about the mechanism of the Fenton process.

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We systematically studied the relation between the conditional auto-correlation function (CACF) and cross-correlation function (CCF) of biphotons or pairs of single photons. The biphotons were generated from a heated atomic vapor via the spontaneous four-wave mixing (SFWM) process. In practical usage, one single photon of a pair is utilized as the heralding photon, and another is employed as the heralded photon.

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Background: The common clinical method to evaluate blood loss during pancreaticoduodenectomy (PD) is visual inspection, but most scholars believe that this method is extremely subjective and inaccurate. Currently, there is no accurate, objective method to evaluate the amount of blood loss in PD patients.

Aim: The hemoglobin (Hb) loss method was used to analyze the amount of blood loss during PD, which was compared with the blood loss estimated by traditional visual methods.

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Enterotoxigenic (ETEC) is an important type of pathogenic bacteria that causes diarrhea in humans and young livestock. The pathogen has a high morbidity and mortality rate, resulting in significant economic losses in the pig industry. To effectively prevent piglet diarrhea, we developed a new tetravalent genetically engineered vaccine that specifically targets ETEC.

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Permanganate/sulfite (Mn(VII)/S(IV)) process is a promising pre-oxidation technology for sequestering the emerging organic contaminants in drinking water treatment plant. Iopamidol (IPM), a representative of iodinated X-ray contrast media, has been widely detected in water sources and has the risk of forming iodinated disinfection byproducts (I-DBPs) in water treatment system. In this study, we investigated the evolution of iodine species during the IPM degradation by the Mn(VII)/S(IV) process and its effect on the subsequent formation of I-DBPs during chlorination at pH 7.

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Background: CCN6 is a matricellular protein that critically regulates the tumourigenesis and progression of breast cancer. Although the tumour-suppressive function of CCN6 has been extensively studied, molecular mechanisms regulating protein levels of CCN6 remain largely unclear. This study aims to investigate the regulation of CCN6 by ubiquitination and deubiquitinating enzymes (DUBs) in breast cancer.

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Fe(IV) and Fe(V) are promising oxidants for the selective removal of emerging organic contaminants (EOCs) from water under near-neutral conditions. The Fe(III)-assisted electrochemical oxidation system with a BDD anode (Fe(III)-EOS-BDD system) has been employed to generate Fe(VI), while the generation and contributions of Fe(IV) and Fe(V) have been largely ignored. Thus, we examined the feasibility and involved mechanisms of the selective degradation of EOCs in the Fe(III)-EOS-BDD system under near-neutral conditions.

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Background: Glycosylation involved in various biological function, aberrant glycosylation plays an important role in cancer development and progression. Glycosyltransferase 8 domain containing 1 (GLT8D1) and GLT8D2, as members of the glycosyltransferase family proteins, are associated with transferase activity. However, the association between GLT8D1/2 and gastric cancer (GC) remains unclear.

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Renal fibrosis is a crucial pathological feature of hypertensive renal disease (HRD). In-depth analysis of the pathogenesis of fibrosis is of great significance for the development of new drugs for the treatment of HRD. USP25 is a deubiquitinase that can regulate the progression of many diseases, but its function in the kidney remains unclear.

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Article Synopsis
  • Bismuth-halide-based inorganic-organic hybrid materials (Bi-IOHMs) are promising for luminescence applications because they are low in toxicity and chemically stable.
  • Two specific Bi-IOHMs, [Bpy][BiCl(Phen)] and [PP14][BiCl(Phen)]·0.25HO, were synthesized and characterized, revealing distinct structural features through single-crystal X-ray diffraction and photoluminescent properties under UV light.
  • The differences in their ionic liquid components resulted in varying rigidity and photoluminescence quantum yield, with implications for improved luminescence and temperature sensing capabilities.
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Background And Purpose: The NLR family pyrin domain-containing 3 (NLRP3) inflammasome is activated in many inflammatory conditions. So far, no low MW compounds inhibiting NLRP3 have entered clinical use. Identification of naturally occurring NLRP3 inhibitors may be beneficial to the design and development of compounds targeting NLRP3.

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Objective: To develop a trivalent genetically engineered inactivated Escherichia coli vaccine (K88ac-3STa-LTB) that neutralizes the STa toxin by targeting fimbriae and entertoxins for the treatment of enterotoxigenic E coli.

Animals: 18- to 22-g mice, rabbits, pregnant sows.

Procedures: Using PCR, the K88ac gene and LTB gene were cloned separately from the template C83902 plasmid.

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Background: The use of vonoprazan (VPZ) has improved the () eradication therapy in Japan. There is no agreement on the dosage and frequency of amoxicillin administration in the VPZ dual treatment in China. We aimed to investigate the clinical effectiveness and safety of 3 treatment regimens using VPZ as an acid-suppressing medication to eradicate .

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During oxidative treatment of iodide (I )-containing waters, I is easy to be oxidized into hypoiodous acid (HOI) by various oxidants and the further reaction of HOI with organic compounds can lead to the formation of iodinated disinfection by-products (I-DBPs). Oxidation of HOI to iodate (IO ) or reduction of HOI to I has been proposed to reduce the formation of I-DBPs. Because the reaction of HOI with sulfite proceeds rapidly, this study examined the fate of iodine and the formation of I-DBPs in Mn(VII)/sulfite process.

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The corrosion of Fe(0) in the presence of O in nature can lead to the oxidation of organic compounds, but the efficiency is very limited. Herein, attempts were made to establish a galvanic system that separates the anodic Fe(0) oxidation reaction and the cathodic O reduction reaction using an air-breathing cathode. Compared with the chemical Fe(0)/O system, it exhibited a substantially higher capability of destroying a variety of pollutants, such as organic dyes (12 types), phenol, nitrobenzene, acetaminophen, phenol, and ethylenediaminetetraacetic acid.

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Oolong tea is one of the world's most popular non-alcoholic beverages, particularly in coastal Southeast China. Hitherto, epidemiological studies on the association between oolong tea consumption and the risk of patients with oral squamous cell carcinoma (OSCC) are very limited. This study aimed to evaluate the potential effect of oolong tea consumption on OSCC risk in Southeast China.

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