Comparison of efficacy and usability of custom mandibular advancement devices fabricated with the conventional method and digital workflow: A pilot clinical study.

Purpose: To compare the effects of fabricating methods of custom monoblock mandibular advancement devices (MADs) on usability and efficacy in patients with mild and moderate obstructive sleep apnea (OSA).

Materials And Methods: Digitally fabricated custom MADs (dMADs) were produced for 11 OSA participants who had previously used conventionally fabricated custom MADs (cMADs). The participants answered a modified usability questionnaire for both MADs, and the average scores that were given to the questionnaire were evaluated by age, sex, and body mass index (BMI), and the scores of cMADs and dMADs were compared.

Discovery of Small Molecule COX-1 and Akt Inhibitors as Anti-NSCLC Agents Endowed with Anti-Inflammatory Action.

Targeted therapies have come into prominence in the ongoing battle against non-small cell lung cancer (NSCLC) because of the shortcomings of traditional chemotherapy. In this context, indole-based small molecules, which were synthesized efficiently, were subjected to an in vitro colorimetric assay to evaluate their cyclooxygenase (COX) inhibitory profiles. Compounds and were found to be the most selective COX-1 inhibitors in this series with IC values of 8.

Fabricating a custom monoblock mandibular advancement device by using an open-source nondental CAD software program and additive manufacturing: A dental technique.

Custom mandibular advancement devices (MADs) can be fabricated by using either conventional processes or computer-aided design and computer-aided manufacturing (CAD-CAM). The CAD-CAM technique involves digitizing the dental arches of the patients, designing by using a dental CAD software program, and additive manufacturing with a suitable material. This article describes the steps of the design of a custom MAD by using an open-source nondental CAD software program and of the fabrication with additive manufacturing.

Design and fabrication of an interim fixed restoration with an open-source nondental CAD software program and additive manufacturing: A technical report.

This technique aimed to identify the potential of an open-source software program and to present the design and fabrication procedures of a single interim crown with a nondental CAD software program. The steps included defining the margins, establishing the cement interval value, completing the virtual modeling of the crown, and checking the proximal and occlusal contacts by using color mapping.

Effects of sintering protocol and dipping time on the optical properties of monolithic zirconia.

Statement Of Problem: The use of monolithic zirconia for restorations has become popular. However, the effects of the coloring process and sintering procedure on the optical properties of monolithic zirconia remain unclear.

Purpose: The purpose of this in vitro study was to evaluate the effects of the different sintering protocols and dipping times on the CIELab color parameters, color difference (ΔE), translucency parameter (TP), opalescence parameter (OP), and contrast ratio (CR) of monolithic zirconia.

Novel and known myxobolids (Cnidaria, Myxozoa) infecting Chondrostoma angorense (Cypriniformes: Leuciscidae) in Turkey.

Turkey has more than 200 endemic freshwater fish species, one of which is the Ankara nase, Chondrostoma angorense Elvira, 1987 (Cypriniformes: Leuciscidae), a food fish in northern Turkey. Like most endemic fish species in Turkey, its myxosporean parasite fauna (Cnidaria: Myxosporea) are not yet described. We surveyed twenty C.

Four novel Myxobolus species (Cnidaria: Myxozoa) infecting Anatolian khramulya Capoeta tinca (Cyprinidae) in northern Turkey.

We identified Myxobolus anatolicus Pekmezci, Yardimci, Yilmaz & Polat, 2014 and 4 novel Myxobolus species from the Anatolian khramulya Capoeta tinca (Cyprinidae) in northern Turkey based on morphology, histology, and phylogenetic analysis. M. karaeri sp.

Effect of fabrication techniques on the optical properties of zirconia-based systems.

Statement Of Problem: How the optical properties of zirconia restorations are affected by their differing processing techniques is unclear.

Purpose: The purpose of this in vitro study was to evaluate the effects of 5 different fabrication techniques on the optical properties of zirconia-based systems, including the color difference between the corresponding shades (ΔE∗, ΔE), translucency parameter, opalescence parameter, and fluorescence (ΔE∗-FL).

Material And Methods: Sixty zirconia disks (IPS e.

The prevalence of childhood psychopathology in Turkey: a cross-sectional multicenter nationwide study (EPICPAT-T).

Aim: The aim of this study was to determine the prevalence of childhood psychopathologies in Turkey.

Method: A nation-wide, randomly selected, representative population of 5830 children (6-13 years-old) enrolled as a 2nd,3rd or 4th grade student in 30 cities were evaluated for presence of a psychiatric or mental disorder by a Sociodemographic Form, Kiddie Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version (K-SADS-PL), and DSM-IV-Based Screening Scale for Disruptive Behavior Disorders in Children and Adolescents scales. Impairment criterion was assessed via a 3 point-Likert scale by the parent and the teacher independently.

Effect of Veneering Techniques on Shear and Microtensile Bond Strengths of Zirconia-Based All-Ceramic Systems.

Purpose: To evaluate shear (SBS) and microtensile (μTBS) bond strengths of zirconia cores veneered using different fabrication techniques.

Materials And Methods: Seventy-five IPS e.max ZirCAD plates were fabricated and divided into three groups according to the following veneering techniques: layering, pressing, and CAD-on.

Impact of Symptoms of Maternal Anxiety and Depression on Quality of Life of Children with Cerebral Palsy.

Introduction: Cerebral palsy (CP) interferes with the quality of life (QOL) of children with CP, and given that parents report having to often guide their children's decision making, it is important to understand the psychosocial factors that have a potential influence on parent-proxy reports. The purpose of this study was to investigate the impact of maternal anxiety and depression symptoms on parent proxy-reported health-related QOL (HRQOL) for children with CP, while controlling other clinical and demographical variables that may have affect HRQOL.

Methods: The HRQOL scores of 97 outpatients with CP, aged 7-18 years, were assessed using the Pediatric QOL Inventory, Parent version (PedsQL-P).

An assessment of marital adjustment in patients with rheumatoid arthritis.

Aim To investigate marital adjustment in patients with rheumatoid arthritis and factors affecting this. Methods A total of 32 patients diagnosed with Steinbrocker class 1-2 rheumatoid arthritis and 32 healthy individuals from a similar age group were included. Sociodemographic characteristics, the Beck Depression Inventory (BDI), short-form 36(SF-36) and the dyadic adjustment scale (DAS) were evaluated in both groups.

Evaluation of paravertebral muscle atrophy and fatty degeneration in ankylosing spondylitis.

Aim: The purpose of this study was to assess morphological changes in the paravertebral muscles in patients with ankylosing spondylitis.

Materials And Methods: Fifty-one patients diagnosed with ankylosing spondylitis and a 50 member control group were included in the study. The surface area of the multifidus and erector spinae muscles was measured at four levels between L1 and L5, and fatty degeneration in these muscles was scored.

The Relationship Between Parental Affective Temperament Traits and Disruptive Behavior Disorders Symptoms in Children With ADHD.

Objective: This study investigated the relationship between parental affective temperaments and the oppositional defiant disorder (ODD) and conduct disorder (CD) symptoms of children with ADHD.

Method: The sample consisted of 542 treatment-naive children with ADHD and their biological parents. Children were assessed via both parent- and teacher-rated behavioral disorder scales.

Effect of Different Surface Treatments on the Bond Strength of Lithium Disilicate Ceramic to the Zirconia Core.

Objective: The aim of this study was to evaluate the effect of different surface treatments [sandblasting, Erbium:Yttrium-Aluminium-Garnet (Er:YAG), and femtosecond lasers] on the shear bond strength (SBS) of the CAD-on technique.

Background Data: Although demand for all-ceramic restorations has increased, chipping remains one of the major problems for zirconia-based restorations.

Materials And Methods: Forty yttrium-stabilized tetragonal zirconia polycrystalline (Y-TZP) zirconia plates (IPS e.

Association of Reactive-Proactive Aggression and Anxiety Sensitivity with Internalizing and Externalizing Symptoms in Children with Attention-Deficit/Hyperactivity Disorder.

This study evaluates the associations among the symptoms of anxiety, depression, and disruptive behavioral disorders (DBD) in the context of their relationships with reactive-proactive aggression and anxiety sensitivity in children with attention-deficit/hyperactivity disorder (ADHD). The sample consisted of 342 treatment-naive children with ADHD. The severity of ADHD and DBD symptoms were assessed via parent- and teacher-rated inventories.

Relationships among depression, anxiety, anxiety sensitivity, and perceived social support in adolescents with conversion disorder.

Objective: This study aimed to assess the relationships of depression, anxiety, anxiety sensitivity, and perceived social support with conversion symptoms in adolescents with conversion disorder (CD).

Methods: Fifty outpatients, aged 8-18 years, who had been diagnosed with CD and members of a control group were assessed using the psychological questionnaires.

Results: Compared with controls, adolescents with CD scored higher on the Child Depression Inventory (CDI), Screen for Child Anxiety-related Emotional Disorders (SCARED), Childhood Anxiety Sensitivity Index (CASI) total, CASI physical and cognitive subscales, and Multidimensional Scale of Perceived Social Support family subscale.

The relationship between C-reactive protein rs3091244 polymorphism and ankylosing spondylitis.

Aims: Previous studies have shown that C-reactive protein (CRP) gene polymorphism can be related to inflammatory changes. The present study aimed to examine the association between CRP gene polymorphism and clinical and laboratory findings in ankylosing spondylitis (AS) patients.

Materials And Methods: A total of 80 patients, 40 with AS and 40 controls, were included in the study.

Color Stability of CAD/CAM Fabricated Inlays after Accelerated Artificial Aging.

Purpose: To investigate the influence of accelerated artificial aging on the color stability of three different inlay restorations produced with a CAD/CAM system.

Materials And Methods: Thirty non-carious human mandibular molar teeth were used. The teeth were embedded in autopolymerizing acrylic resin blocks.

[Adaptation of the Childhood Anxiety Sensitivity Index for Use in Turkey].

Objective: Anxiety sensitivity (AS) refers to the fear of anxiety-related sensations. The aim of the present study is to investigate the validity and reliability of Childhood Anxiety Sensitivity Index (CASI) and adapting it into Turkish.

Method: The study group consisted of 328 healthy individuals whose age between 8-15 years old.