The comparison between modified one-portal bankart repair to prevent suture tangling and standard two-portal arthroscopic bankart repair technique.

We have carefully reviewed the letter to the editor by Kushtrim Grezda and deemed it highly noteworthy. To address the issues stated in the letter to the editor, we agreed to prepare the authors' response.

Eligibility of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulator therapies: cohort of cystic fibrosis registry of Türkiye.

Background: Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) variants are essential for determining eligibility for CFTR modulator drugs (CFTRms). In contrast to Europe and the USA, the treatment eligibility profile of cystic fibrosis (CF) patients in Türkiye is not known. In this study we aimed to determine the eligibility of CF patients in Türkiye for the CFTRms.

NETosis: A key player in autoimmunity, COVID-19, and long COVID.

NETosis, the process through which neutrophils release neutrophil extracellular traps (NETs), has emerged as a crucial mechanism in host defense and the pathogenesis of autoimmune responses. During the SARS-CoV-2 pandemic, this process received significant attention due to the central role of neutrophil recruitment and activation in infection control. However, elevated neutrophil levels and dysregulated NET formation have been linked to coagulopathy and endothelial damage, correlating with disease severity and poor prognosis in COVID-19.

Evaluating the push-pull strategy in eastern apple orchards: verbenone effectively reduces ambrosia beetle populations without the need for a pull factor in a species-specific manner.

Background: Non-native ambrosia beetles (Coleoptera: Curculionidae: Scolytinae), specifically Xylosandrus germanus (Blandford), Xylosandrus crassiusculus (Motschulsky), and more recently Anisandrus maiche (Kurentzov) are destructive wood-boring pests of apple trees (Malus domestica). Previous studies have demonstrated all three beetle species are strongly attracted to ethanol and verbenone interrupts their attraction to ethanol. We tested a 'push-pull' management strategy in eastern United States apple orchards in three states New York, Pennsylvania, and Ohio using verbenone sachets to 'push' beetles away from apple trees and high release ethanol lures to 'pull' them into clear sticky traps.

Longitudinal Investigation of Brain and Spinal Cord Pericytes After Inducible PDGFRβ Cell Ablation in Adult Mice.

Central nervous system (CNS) pericytes play crucial roles in vascular development and blood-brain barrier maturation during prenatal development, as well as in regulating cerebral blood flow in adults. They have also been implicated in the pathogenesis of numerous neurological disorders. However, the behavior of pericytes in the adult brain after injury remains poorly understood, partly due to limitations in existing pericyte ablation models.

Repeat Microvascular Decompression for Recurrent Trigeminal Neuralgia.

Introduction: Trigeminal neuralgia (TN) is described as the most excruciating pain typically involving the face. Microvascular decompression (MVD) is regarded as the established method of treatment of the condition. We aimed to detect the underlying pathology in recurrent TN cases, to prevent the recurrence rate of the patients and to determine the difficulties encountered during surgery.

Galectin-3 level in idiopathic pulmonary fibrosis patients and its relationship with response to antifibrotic treatment.

Object: Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease with characterized by progressive fibrosis. Galectin-3(Gal-3) is a B-galactoside binding lectin plays a central role in inflammation and fibrosis. In our study, we aimed to define levels of serum galectin-3 protein in IPF patients by comparing them with healthy subjects.

The Relationship Between Restless Legs Syndrome and Overactive Bladder: A Cross-Sectional, Controlled Study.

Objectives: We aimed to investigate the common mechanisms in restless legs syndrome (RLS) and overactive bladder (OAB), the prevalence of OAB in RLS, and the effects of RLS treatment on OAB.

Methods: Sixty patients newly diagnosed with RLS and 60 healthy individuals in the control group were included in the study. The patients completed the RLS-Severity Rating Scale and were started on pramipexole for treatment.

The Effectiveness of Pelvic Ultrasonography Findings in Diagnosing Precocious Puberty.

Objective: Gonadotropin-releasing hormone (GnRH) stimulation testing is the gold standard for distinguishing central precocious puberty (CPP) from premature thelarche (PT). Due to the limitations of this test, previous studies have elucidated the clinical and laboratory factors that predict CPP. This study explored the diagnostic importance of pelvic ultrasound in girls with CPP.

Is there any room for ChatGPT AI bot in speech-language pathology?

Purpose: This study investigates the potential of the ChatGPT-4.0 artificial intelligence bot to assist speech-language pathologists (SLPs) by assessing its accuracy, comprehensiveness, and relevance in various tasks related to speech, language, and swallowing disorders.

Method: In this cross-sectional descriptive study, 15 practicing SLPs evaluated ChatGPT-4.

Cardioprotective Effects of Dapagliflozin and Trimetazidine on Doxorubicin-Induced Cardiotoxicity in Streptozotocin-Induced Type 1 Diabetic Rats via Endoplasmic Reticulum Stress.

Diabetic cardiomyopathy is a distinct myocardial dysfunction characterized by structural and functional changes in the heart that occur in diabetic patients independently of coronary artery disease or hypertension. It is closely associated with oxidative stress, inflammation, mitochondrial dysfunction, and endoplasmic reticulum (ER) stress, and contributes to progressive cardiac damage. This study aimed to evaluate the cardioprotective effects of dapagliflozin (DAPA) and trimetazidine (TMZ) in a rat model of doxorubicin-induced cardiomyopathy with streptozotocin-induced diabetes, focusing on their potential mechanisms related to ER stress.

Investigation of the Effect of Camellia Sinensis Essence Cream on Skin Burns.

Burn injuries are among the most common causes of trauma globally, affecting millions annually. Current treatments often rely on topical agents, but alternatives to synthetic formulations are increasingly sought due to safety and efficacy concerns. This study aimed to evaluate the therapeutic effects of a cream containing Camellia sinensis (white tea) extract on third-degree burn-induced skin lesions in a rat model.

Patients six months after arthroscopic rotator cuff repair exhibit increased thoracic kyphosis compared to healthy individuals despite standard rehabilitation protocol.

BackgroundShoulder pain is often accompanied by disturbances in spinal posture, such as increased thoracic kyphosis. Moreover, a high prevalence of scapular dyskinesis has been observed in the majority of shoulder pain patients. However, these alterations seen in individuals with shoulder pain have not been thoroughly examined after arthroscopic rotator cuff repair (RCr).

Epidemiological and clinical findings of ocular trauma in a public hospital in Türkiye.

Background: The aim of this study is to characterize the sociodemographic, epidemiological, and clinical characteristics of ocular injuries in a secondary-level public hospital in Türkiye, identify the risk factors in the region, raise awareness on this issue, and propose solutions for injury prevention.

Methods: This hospital-based retrospective cross-sectional study was conducted using data from patients who were followed up and treated for ocular trauma between January 2021 and January 2023 in a secondary-level public hospital located in the Middle Black Sea region of Türkiye. All patients, regardless of age, diagnosed with eyeball, eyelid, and orbital trauma were included.

The Relationship Between Anxiety and Readiness Levels Regarding Artificial Intelligence in Midwives: An Intergenerational Comparative Study.

This study aimed to compare Generations X, Y, and Z in terms of anxiety and readiness levels regarding artificial intelligence and investigate the relationship between anxiety and readiness levels regarding artificial intelligence in midwives across generations. This study is cross-sectional and comparative with a study sample of 218 midwives working in a province in the east of Turkey. Data were collected with the "Personal Information Form," "Artificial Intelligence Anxiety Scale," and "Medical Artificial Intelligence Readiness Scale.

Diagnostic value of bone scintigraphy versus CMR in cardiac amyloidosis.

Objectives And Background: Accurate diagnosis of transthyretin amyloidosis cardiomyopathy (ATTR-CM) and its differentiation from light-chain (AL) cardiac amyloidosis (CA) cases (AL-CM) is of paramount importance, since treatment strategies are totally different and obviously more successful in case of early disease detection. Surprisingly, comparative imaging data based on concurrent cardiovascular magnetic resonance (CMR) and bone scintigraphy in the same patients with biopsy-proven diagnosis of CA are still rare.

Methods: This was a real-world retrospective single-centre study based on a local clinical care pipeline and we carefully analysed clinical, laboratory, CMR, bone scintigraphy data (and if necessary additional endomyocardial biopsy (EMB) data) in patients with suspected CA.

A novel deep learning-based framework with particle swarm optimisation for intrusion detection in computer networks.

Intrusion detection plays a significant role in the provision of information security. The most critical element is the ability to precisely identify different types of intrusions into the network. However, the detection of intrusions poses a important challenge, as many new types of intrusion are now generated by cyber-attackers every day.

Evaluation of intra-abdominal injuries in patients referred to the emergency department as a result of traffic accidents.

Background: Traffic accidents are one of the most important reasons that increase the workload of emergency services all over the world. Especially in developing countries, this problem is difficult to solve due to rapid population growth.

Objective: The aim of this study was to evaluate the causes of mortality and morbidity, the organs affected by the injury, and the prognosis of the patients who are referred to the emergency department as a result of traffic accidents and underwent abdominal imaging.

A risk score to predict kidney survival in patients with autosomal recessive polycystic kidney disease at the age of two months.

Autosomal recessive polycystic kidney disease (ARPKD) is a severe hepatorenal fibrocystic disorder. Its rareness and the variability of disease courses have been major obstacles for the establishment of clinical trials on treatment of kidney disease in ARPKD. In this observational study we characterized kidney disease progression in a very large cohort of up to 658 patients with the clinical diagnosis of ARPKD and identified risk factors associated with rapid kidney disease progression.

Anti-nephrin autoantibodies in steroid-resistant nephrotic syndrome may inform treatment strategy.

Objective: Autoantibodies against the podocyte protein nephrin were recently identified in a pediatric cohort primarily comprising steroid-sensitive (SSNS) and steroid-dependent (SDNS) nephrotic syndrome (NS). However, their prevalence across all NS subtypes, particularly in steroid-resistant nephrotic syndrome (SRNS), and their relation to therapy response remain need to be determined to advance pathophysiological understanding and refine treatment strategies.

Methodology: A multicenter cohort study measuring anti-nephrin autoantibodies in samples from children with SSNS, SDNS, non-genetic and genetic SRNS was conducted.

Long-Term Outcomes of Allogeneic Stem Cell Transplantation for Relapsed/Refractory Hodgkin and Non-Hodgkin Lymphoma: Multi-center Experience from Turkey.

This multicenter retrospective study evaluated the efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) on survival and safety in patients with relapsed/refractory (R/R) Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL). A total of 110 patients with R/R HL or NHL who underwent allo-HSCT between July 2007 and October 2022 at 7 adult stem cell transplant centers were evaluated. Progression-free survival (PFS), graft versus host disease-free survival (GRFS), and overall survival (OS) were the primary endpoints, and NRM was the secondary endpoint.