Publications by authors named "Yiling Kong"
Article Synopsis
- Porcine reproductive and respiratory syndrome (PRRS) is a major global disease that weakens pigs' immune systems, with Nsp4 identified as a key target for inhibitors.
- This study screened natural compounds to find those that can inhibit PRRSV replication by binding to Nsp4, using molecular docking techniques.
- Three compounds—naringin dihydrochalcone (NDC), agathisflavone (AGT), and amentoflavone (AMF)—showed strong binding affinity and stability, suggesting they could be promising candidates for developing new anti-PRRSV medications.
Hemophagocytic lymphohistiocytosis (HLH) can be classified into primary HLH and secondary HLH. Primary HLH usually occurs in infants and children with an underlying genetic defect, and there are also teens and occasional adults with primary HLH. Most cases with secondary HLH are adult patients with secondary triggers including infections, malignancies, and autoimmune diseases.
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