The nonspecific anti-inflammatory therapy with methotrexate for patients with chronic heart failure.

Background: Inflammatory mediators play an important role in the pathogenesis of chronic heart failure (CHF). Methotrexate (MTX) is used in the treatment of inflammatory-mediated diseases (eg, rheumatoid arthritis) because it modulates the expression of numerous inflammatory cytokines. However, no studies have assessed the effects of MTX on plasma levels of inflammatory mediators in patients with CHF.

[Effect of shuxuetong in preventing restenosis after intracoronary stenting].

Objective: To evaluate the effect of shuxuetong (SXT) in preventing restenosis after intracoronary stenting.

Methods: Sixty-eight patients, accepted intracoronary stenting, were divided into two groups, the SXT group and the control group, both of them were treated with conventional treatment, and to the SXT group, SXT was given additionally. The condition of treated coronary artery restenosis in the two groups was compared by way of quantitative coronary angiography and a 6-month follow-up study was adopted.