Arthroscopic Resection for Extra-articular Ganglion Cysts of Gastrocnemius Near Vessels.

Extra-articular ganglion cysts arising from the gastrocnemius tendon near popliteal vessels can cause pain and claudication. Open resection of this kind of cyst has been described frequently because the vessels can be well protected with a retractor. However, it's a challenge to remove cysts that are near vessels under arthroscopy, because a retractor cannot be used in arthroscopic surgery.

A Hybrid Scaffold Induces Chondrogenic Differentiation and Enhances Cartilage Regeneration.

Extensively researched tissue engineering strategies involve incorporating cells into suitable biomaterials, offering promising alternatives to boost tissue repair. In this study, a hybrid scaffold, Gel-DCM, which integrates a photoreactive gelatin-hyaluronic acid hydrogel (Gel) with an oriented porous decellularized cartilage matrix (DCM), was designed to facilitate chondrogenic differentiation and cartilage repair. The Gel-DCM exhibited excellent biocompatibility , promoting favorable survival and growth of human adipose-derived stem cells (hADSCs) and articular chondrocytes (hACs).

Analysis of differentially expressed genes in torn rotator cuff tendon tissues in diabetic patients through RNA-sequencing.

Background: Rotator cuff tears (RCT) is a common musculoskeletal disorder in the shoulder which cause pain and functional disability. Diabetes mellitus (DM) is characterized by impaired ability of producing or responding to insulin and has been reported to act as a risk factor of the progression of rotator cuff tendinopathy and tear. Long non-coding RNAs (lncRNAs) are involved in the development of various diseases, but little is known about their potential roles involved in RCT of diabetic patients.

Stem Cell Applications and Tenogenic Differentiation Strategies for Tendon Repair.

Tendons are associated with a high injury risk because of their overuse and age-related tissue degeneration. Thus, tendon injuries pose great clinical and economic challenges to the society. Unfortunately, the natural healing capacity of tendons is far from perfect, and they respond poorly to conventional treatments when injured.

Tendon Stem/Progenitor Cell-Laden Nanofiber Hydrogel Enhanced Functional Repair of Patellar Tendon.

Functional repair of tendons remains a challenge to be overcome for both clinicians and scientists. We have previously reported a three-dimensional RADA peptide hydrogel that provides a suitable microenvironment for human tendon stem/progenitor cells (TSPCs) survival and tenogenesis. In this study, we explore the potential of patellar tendon repair by human TSPC-laden RADA hydrogel in rats, which were sacrificed at 4 and 8 weeks after operation.

Two-type classification system for femoral trochlear dysplasia in recurrent patellar instability based on three-dimensional morphology.

Purpose: Radiographic and two-dimensional (2D) CT/MRI analysis of femoral trochlear dysplasia play a significant role in surgical decision-making for recurrent patellar instability. However, the three-dimensional morphology of dysplastic trochlea is rarely studied due to the limitations of conventional imaging modalities. This study aimed to (1) develop a 3D morphological classification for trochlear dysplasia based on the concavity of the trochlear groove and (2) analyze the interrater reliability of the classification system.

Effects of Perioperative Fascia Iliaca Compartment Block on Postoperative Pain and Hip Function in Elderly Patients With Hip Fracture.

Purpose: Pain management is a challenging issue in elderly patients with hip fracture. Despite the accepted clinical outcomes following hip surgery, pain and prolonged recovery time are the most difficult consequences associated with the rehabilitation process. The purpose of this study was to evaluate pain relief and functional improvement associated with the Fascia Iliaca Compartment Block (FICB) during the perioperative period of elderly patients with hip fracture.

Experimental study of the effects of hypoxia simulator on osteointegration of titanium prosthesis in osteoporotic rats.

Background: Poor osseointegration is the key reason for implant failure after arthroplasty,whether under osteoporotic or normal bone conditions. To date, osseointegration remains a major challenge. Recent studies have shown that deferoxamine (DFO) can accelerate osteogenesis by activating the hypoxia signaling pathway.

Patient-Reported Outcomes and Risk Factors for Decreased Improvement after Patellofemoral Arthroplasty.

Patellofemoral arthroplasty (PFA) is acknowledged as the method for the treatment of isolated patellofemoral osteoarthritis (PFOA). Few previous studies have assessed the patient-reported outcomes (PROs) and risk factors of less improvement of PROs in patients undergoing PFA. A retrospective analysis was performed, including all patients who had undergone PFA.

Association of patellofemoral morphology and alignment with the radiographic severity of patellofemoral osteoarthritis.

Background: Risk factors for the severity of patellofemoral osteoarthritis (PFOA) are poorly understood. This research aims to evaluate the association between patellofemoral joint (PFJ) morphology and alignment with the radiographic severity of PFOA.

Methods: A retrospective analysis of CT scan and lateral radiograph data were acquired in patients with PFOA.

Joint Awareness after Patellofemoral Arthroplasty Evaluated with the Forgotten Joint Score: A Comparison Study.

Objective: The aim of the present study was to compare the forgotten joint score (FJS) in patients with isolated patellofemoral osteoarthritis who underwent patellofemoral arthroplasty (PFA) versus those who underwent total knee arthroplasty (TKA) and to analyze the predictors of the FJS after PFA.

Methods: From January 2014 to December 2017, a retrospective cohort study of 56 consecutive patients with isolated patellofemoral osteoarthritis underwent PFA and were included in the PFA group. The patients in the PFA group were matched in a 1:1 ratio based on age, sex, body mass index (BMI), and follow-up duration; 56 patients with isolated patellofemoral osteoarthritis underwent cruciate-retaining TKA (TKA group).

Early patellofemoral articular cartilage degeneration in a rat model of patellar instability is associated with activation of the NF-κB signaling pathway.

Background: Patellar instability (PI) often increases the possibility of lateral patellar dislocation and early osteoarthritis. The molecular mechanism of early articular cartilage degeneration during patellofemoral osteoarthritis (PFOA) still requires further investigation. However, it is known that the NF-κB signaling pathway plays an important role in articular cartilage degeneration.

Pigmented villonodular synovitis does not influence the outcomes following cruciate-retaining total knee arthroplasty: a case-control study with minimum 5-year follow-up.

Background: Pigmented villonodular synovitis (PVNS) is a rare synovial disease with benign hyperplasia, which has been successfully treated with total knee arthroplasty (TKA). The purpose of this study was to investigate the middle-term follow-up outcomes of cruciate-retaining (CR) TKA in patients with PVNS.

Methods: From January 2012 to December 2014, a retrospective study was conducted in 17 patients with PVNS who underwent CR TKA as PVNS group.

Patellofemoral Arthroplasty Improves Patellofemoral Alignment in Patients with Patellofemoral Osteoarthritis with Trochlear Dysplasia.

The impact of trochlear dysplasia on patellofemoral arthroplasty (PFA) has rarely been reported in the literature. The purpose of this study was to explore the effectiveness of PFA in patients with patellofemoral osteoarthritis (PFOA) associated with trochlear dysplasia. From January 2014 to March 2018, 35 patients with PFOA and trochlear dysplasia (29 females and 6 males), underwent PFA, were included in the present retrospective study.

Mini-midvastus versus medial parapatellar approach in total knee arthroplasty: difference in patient-reported outcomes measured with the Forgotten Joint Score.

Background: Low knee awareness after minimally invasive total knee arthroplasty (TKA) has become the ultimate target of a natural-feeling knee that meets patient expectations. The objective of this research was to compare the clinical outcomes of TKA via the mini-midvastus (MMV) approach or the medial parapatellar (MPP) approach, and to evaluate which approach can lead to a better quality of life after surgery.

Methods: From January 2015 to December 2016, a retrospective cohort study was conducted in 330 patients who underwent TKA via a mini-midvastus (MMV) approach.

A surgical reduction technique for posterior cruciate ligament avulsion fracture in total knee arthroplasty: a comparison study.

Background: Posterior cruciate ligament (PCL) avulsion fracture of the tibia is an uncommon but serious complication during primary cruciate-retaining total knee arthroplasty (TKA). The first objective of this report was to conduct a retrospective cohort study to investigate the incidence and potential risk factors of PCL avulsion fracture in primary cruciate-retaining TKA. The second objective was to assess the functional outcomes of the knee after reduction of PCL avulsion fracture.

Scalpel can achieve better clinical outcomes compared with electric cautery in primary total knee arthroplasty: a comparison study.

Background: Whether using the scalpel can provide better and faster recovery after the primary total knee arthroplasty (TKA) is still controversial. The aim of this research was to compare the clinical outcomes of using the scalpel and the electric cautery in primary TKA.

Methods: From January 2016 to December 2017, a retrospective cohort study was conducted in 313 patients who underwent unilateral primary TKA by using the scalpel (group S).

Distal femoral morphological dysplasia is correlated with increased femoral torsion in patients with trochlear dysplasia and patellar instability.

Aims: The purpose of this study was to explore the correlation between femoral torsion and morphology of the distal femoral condyle in patients with trochlear dysplasia and lateral patellar instability.

Methods: A total of 90 patients (64 female, 26 male; mean age 22.1 years (SD 7.

The effect of increased femoral anteversion on the morphological and trabecular microarchitectural changes in the trochlea in an immature rabbit.

Increased femoral anteversion (FA) has been recently demonstrated as one risk factor for recurrent patellar dislocation (RPD). However, it has been still unclear whether the increase of FA can result in patellar dislocation, and subsequent morphological and trabecular microarchitectural changes in the trochlea has not been investigated. Forty knees from 20 rabbits at 3 months of age were included.

Joint Awareness after Unicompartmental Knee Arthroplasty Evaluated with the Forgotten Joint Score.

Objective: To investigate the temporal relationship of medial unicompartmental knee arthroplasty (UKA) and forgotten joint score (FJS), and to analysis the predictive factors associated with FJS after medial UKA.

Methods: This is a cross-sectional observational study. A total of 188 cases of medial UKA were included in this study, and all the prostheses used were Oxford mobile-bearing UKA from January 2016 to January 2019.

Changes in cartilage and subchondral bone in a growing rabbit experimental model of developmental trochlear dysplasia of the knee.

: Trochlear dysplasia is one of the most frequent lower extremities deformities. Aim of this research was to investigate the changes in cartilage and subchondral bone of trochlea after patellar dislocation in growing rabbits. : Ninety-six knees from 48 one-month-old rabbits were divided into two groups (experimental, control).

The dysplastic trochlear sulcus due to the insufficient patellar stress in growing rats.

Background: Developmental factors were assumed to be the key factors that influenced the morphology of femoral trochlea. This study investigated the effects of insufficient patellar stress after birth on the morphological development of the femoral trochlea. Effects of insufficient patellar stress on femoral trochlea were investigated using surgical induced patellectomy and patellar dislocation in growing rat model.