Reflective analysis on the current I adjuvant therapy indications in intermediate- and high-risk differentiated thyroid cancer.

Purpose: Radioiodine (I) adjuvant therapy (RAT) is given to treat subclinical tumor of differentiated thyroid cancer (DTC) that may or may not actually be present after prior adequate treatment, yet the indications and benefits for RAT remain controversial. This multi-center study retrospectively evaluated the real targets and responses to RAT in intermediate- and high-risk patients, aiming to refine current "one-size-fits-all" guidelines.

Methods: Totally 599 intermediate- and high-risk DTC patients from three centers were enrolled.

Risk factors for extraurothelial recurrence in upper tract urothelial carcinoma after radical nephroureterectomy: a retrospective study based on a Chinese population.

Objectives: The risk factors for extraurothelial recurrence (EUR) after radical nephroureterectomy (RNU) in patients with upper urinary tract urothelial carcinoma (UTUC) are currently inconsistent and unclear. In this study, we aimed to identify these risk factors and develop a grading system for EUR.

Methods: We retrospectively analyzed 220 patients who underwent RNU for UTUC in our center from January 2009 to December 2020.

Correlation between the timing of diagnostic ureteroscopy for upper tract urothelial cancer and intravesical recurrence after radical nephroureterectomy.

Objective: We aimed to evaluate the effect of the timing of diagnostic ureteroscopy (URS) on intravesical recurrence (IVR) following radical nephroureterectomy (RNU).

Patients And Methods: The clinical data of 220 patients with upper tract urothelial carcinoma (UTUC) treated with RNU at our center from June 2010 to December 2020 were retrospectively analyzed. According to the timing of the URS, all patients were divided into three groups: the no URS group, the 1-session group (diagnostic URS immediately followed by RNU), and the 2-session group (RNU after diagnostic URS).

Associations between NK Cells in Different Immune Organs and Cellular SIV DNA and RNA in Regional HLADR CD4 T Cells in Chronically SIV-Infected, Treatment-Naïve Rhesus Macaques.

With the development of NK cell-directed therapeutic strategies, the actual effect of NK cells on the cellular SIV DNA levels of the virus in SIV-infected macaques in vivo remains unclear. In this study, five chronically SIV-infected, treatment-naïve rhesus macaques were euthanized, and the blood, spleen, pararectal/paracolonic lymph nodes (PaLNs), and axillary lymph nodes (ALNs) were collected. The distributional, phenotypic, and functional profiles of NK cells were detected by flow cytometry.

Impact of LED transmitters' radiation pattern on received power distribution in a generalized indoor VLC system.

This paper analyzes the received power distribution of a generalized indoor visible light communication (VLC) system. The generalization includes: both ceiling-mounted and wall-mounted layouts are considered on the transmitting end to cover some special scenarios; a generally applicable sum-of-sine luminous intensity pattern (SSLIP) is used to fit light emitting diodes (LEDs)' radiation curve; the receiver is considered to have a large light receiving area (LRA) with non-uniformly distributed received power. Through mathematical calculation, the expression of received power at any point of the room is derived.