Visible Light-Mediated Late-Stage Thioetherification of Mercaptopurine Derivatives.

We disclose herein a novel and general radical approach to alkylthiopurines, encompassing 4 types of thiopurines, as well as their corresponding ribosides. This strategy is achieved through visible light-mediated late-stage functionalization of the sulfur atoms of mercaptopurines. The in situ-generated disulfide was proposed as the pivotal neutral intermediate for this transformation.

Mesoscopic Analysis of Rounded and Hybrid Aggregates in Recycled Rubber Concrete.

Recycled rubber concrete (RRC), a sustainable building material, provides a solution to the environmental issues posed by rubber waste. This research introduces a sophisticated hybrid random aggregate model for RRC. The model is established by combining convex polygon aggregates and rounded rubber co-casting schemes with supplemental tools developed in MATLAB and Fortran for processing.

Analysis of Mechanical Properties and Failure Mechanism of Lightweight Aggregate Concrete Based on Meso Level.

The relationship between the macroscopic mechanical properties of lightweight aggregate concrete and its microstructure is a hot topic in the discipline of concrete materials. It is very meaningful to provide an efficient numerical analysis method to conduct a meso-level analysis. This study proposes an automatic dissection algorithm and adapts the calculation program of the base force element method to conduct a non-linear damage analysis.

Analysis of Tensile Strength and Failure Mechanism Based on Parallel Homogenization Model for Recycled Concrete.

In this paper, a parallel homogenization model for recycled concrete was proposed. A new type of finite element method, the base force element method, based on the complementary energy principle and the parallel homogenization model, is used to conduct meso-level damage research on recycled concrete. The stress-strain softening curve and failure mechanism of the recycled concrete under uniaxial tensile load are analyzed using the nonlinear damage analysis program of the base force element method based on the parallel homogenization model.

Numerical Simulation of Dynamic Mechanical Properties of Concrete under Uniaxial Compression.

Based on the base force element method (BFEM), the dynamic mechanical behavior of concrete under uniaxial compression loading at different strain rates is investigated. The concrete can be considered as a three-phase composite material composed of aggregate, cement mortar, and interfacial transition zone (ITZ) on the meso-level. A two-dimensional random aggregate model is generated by the Monte Carlo method.