Publications by authors named "Yihua Guo"
Glucagon is essential for glucose homeostasis, and its dysregulation is associated with diabetes. Despite extensive research, the mechanisms governing glucagon secretion remain incompletely understood. Here, we unveil that famsin, a gut-secreted hormone, promotes glucagon release and modulates glucose homeostasis.
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- - The study investigates the effectiveness and safety of vamorolone, a treatment for Duchenne muscular dystrophy (DMD), comparing its effects at different doses and against standard glucocorticosteroids like prednisone and deflazacort.
- - A systematic search and meta-analysis of 193 patients from four clinical trials were conducted to analyze the results, focusing on various performance measures such as TTSTANDV and 6MWT to assess efficacy.
- - The findings indicated significant benefits of higher vamorolone doses over lower ones in various metrics, while also evaluating the safety profile of vamorolone compared to traditional treatments like prednisone.
Purpose: To investigate the optimal agent combined with propofol for sedation in elderly patients undergoing gastrointestinal endoscopy.
Methods: A total of 120 elderly patients scheduled for gastrointestinal endoscopy under propofol-based sedation were randomly allocated to receive propofol + saline (control group), propofol + sufentanil 0.1 μg/kg, propofol + dexmedetomidine 0.
Article Synopsis
- The study examined asthma prevalence and risk factors in children aged 0-14 years in Fuzhou, China, highlighting an increase from 1.57% in 1990 to 3.28% in 2000, and further to 1.83% in 2010.
- A total of 12,235 parents were surveyed, with 648 reporting asthma symptoms; however, only 485 children were confirmed to have asthma, indicating a disparity in reported versus diagnosed cases.
- Significant risk factors for asthma included having atopic diseases, family history of allergies, antibiotic use in the first year, and early protein feeding, while natural home ventilation was associated with lower asthma risk.
Objective: To explore the prevalence and the different risk factors for asthma in children between urban and rural areas in Fuzhou, Fujian province.
Method: The epidemiological survey of asthma in 0-14 years old children was conducted from October 2009 to October 2010 between Fuzhou urban and rural areas in Fujian province. The investigation subjects were selected in urban and rural areas by phased stratified random cluster sampling.
[Effect of nasal cavity expansion surgery on chronic nasal obstructive diseases on the blood supply of the cerebral arterial system].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
September 2013
Objective: To investigate the effect of nasal cavity expansion surgery on the abnormal blood supply of the cerebral arterial system.
Methods: Fifty-nine inpatients with abnormal blood supply of cerebral arterial system confirmed by transcranial doppler (TCD) and chronic nasal obstructive diseases were included in this study. All patients accepted nasal cavity expansion surgery and were followed-up with TCD every month after operation until TCD became normal, or up to seven months even if the TCD was still abnormal.
[Etiological analysis of the children with non-specific chronic cough in Fuzhou area of Fujian province].
Zhonghua Er Ke Za Zhi
February 2011
Objective: Chronic cough in children is a common pediatric symptom with complex causes and its diagnosis is difficult; chronic cough affects the life of children in both physical and mental health and also learning. Therefore this study aimed to investigate the causes of chronic cough in children in Fuzhou area of Fujian province.
Method: Data were collected from 364 children with chronic cough who visited the asthma specialist clinic of Children's Hospital of Fuzhou, Fujian Province from March 2009 to April 2010.