Tumor budding is an optimal indictor of occult cervical metastasis in clinical early-stage buccal mucosa squamous cell carcinoma.

Background: Buccal mucosa squamous cell carcinoma (BMSCC) is an aggressive disease. This study investigated the clinicopathological significance of tumor budding (TB), depth of invasion (DOI), and mode of invasion (MOI) on occult cervical metastasis (CM) of BMSCC.

Methods: Seventy-one cTN BMSCC patients were included in this retrospective study.

Simultaneous realization of high gain and low DMG of four-mode EDFA under bidirectional hybrid-mode pump.

We theoretically and experimentally verify that, the bidirectional hybrid-mode pumping scheme can address the optimization problem of trade-off between high gain and low differential modal gain (DMG) of four-mode erbium-doped fiber amplifier (4M-EDFA), in comparison with traditional both forward and backward hybrid-mode pumping scheme. It is noticed that, when the total pump power is fixed, the bidirectional hybrid-mode pumping scheme can not only achieve higher gain, but also suppress DMG due to different overlap integrals for the forward and backward pumping schemes. The bidirectional hybrid-mode pumped 4M-EDFA is developed with the forward pumping at LP mode and the backward pumping at LP mode, under a pump power ratio of 30%:70%.

Association between exposure to multiple polyaromatic hydrocarbons and periodontitis: findings from a cross-sectional study.

The impact of environmental pollutant exposure on periodontitis has raised significant concerns. But the association between exposure to multiple polyaromatic hydrocarbons (PAHs) and periodontitis still remained unclear. Our study investigated the association of exposure to multiple PAHs with periodontitis.

Mandible reconstruction with free fibula flaps: Accuracy of a cost-effective modified semicomputer-assisted surgery compared with computer-assisted surgery - A retrospective study.

A new individualized, cost-effective, modified semi-computer-assisted surgery (MSCAS) concept for free fibular flap mandibular reconstruction is reported and compared with the computer-assisted surgery (CAS) concept. Patients were divided into two groups and retrospectively reviewed. In the MSCAS and CAS groups, intraoperative guides were created using computer-aided design with manual fabrication and computer-aided design and manufacturing, respectively.

Case Report: Superficial Circumflex Iliac Artery Perforator Flap for Tongue Reconstruction Following the Hemiglossectomy.

Therapeutic evaluation of applying superficial circumflex iliac artery perforator (SCIP) flap in tongue reconstruction after hemiglossectomy. We retrospectively collected a total number of 14 patients who received SCIP flap reconstruction for tongue defects at the Fujian Medical University affiliated Union Hospital, between November 2016 and November 2020. We evaluated the clinical features of the flap, analyzed the postoperative functions and esthetic effects after 6 months of the tongue reconstruction.

Refractive index sensor based on multiple Fano resonances in a plasmonic MIM structure.

A chip-scale refractive index sensor based on multiple Fano resonances is proposed by using a metal-insulator-metal (MIM) structure, which is constructed by two side-coupled semi-ring cavities and a vertical cavity. The finite-difference time-domain method and multimode interference coupled-mode theory are employed to simulate and analyze the transmission spectra of this structure, respectively. First, dual Fano resonances are generated in the MIM structure with a baffle and a semi-ring cavity.

Study of AsO regulating proliferation and apoptosis of Tca8113 cells by inhibiting the expression of Id-1.

Objective: Our study aims to investigate the effect of arsenic trioxide (AsO) on proliferation and apoptosis of Tca8113 tongue squamous carcinoma cells.

Methods: Cell proliferation and the expression of Id-1 mRNA in Tca8113 cells after treatment with different concentrations of AsO were detected by MTT and qRT-PCR, respectively. The expression of Id-1, cell proliferation and apoptosis in Id-1 silencing Tca8113 cells were detected by qRT-PCR, Western blot, MTT and flow cytometry, respectively.

Plasmonic-induced absorption based on an end-coupled combined resonance system of a semiannular cavity and rectangular cavity.

A semiannular rectangular composite cavity structure based on metal-insulator-metal waveguides is proposed. By adding a rectangular cavity at a suitable position around the semiannular cavity (SAC), a single analogous plasmonic-induced absorption (PIA) effect is achieved at the expected mode of the SAC structure. After adding two rectangular cavities together in the SAC system, dual analogous PIA effects for both modes can be realized simultaneously.

A Plasmonic Chip-Scale Refractive Index Sensor Design Based on Multiple Fano Resonances.

In this paper, multiple Fano resonances preferred in the refractive index sensing area are achieved based on sub-wavelength metal-insulator-metal (MIM) waveguides. Two slot cavities, which are placed between or above the MIM waveguides, can support the bright modes or the dark modes, respectively. Owing to the mode interferences, dual Fano resonances with obvious asymmetrical spectral responses are achieved.

Plasmonic filter and sensor based on a subwavelength end-coupled hexagonal resonator.

In this paper, an end-coupled hexagonal resonator inserted with dual parallel metallic blocks is proposed based on subwavelength metal-insulator-metal waveguides. When the blocks are vertically inserted into the resonator, more transmission channels (three peaks) with symmetrical spectral shapes than that (one peak) of the perfect hexagonal resonator are achieved in the same wavelength range. The transmission peaks all have high transmittances; thus, the structure can be performed as an on-chip optical filter.

Plasmonic Multichannel Refractive Index Sensor Based on Subwavelength Tangent-Ring Metal⁻Insulator⁻Metal Waveguide.

In this paper, a multichannel refractive index sensor based on a subwavelength metal⁻insulator⁻metal (MIM) waveguide coupled with tangent-ring resonators is proposed. When two tangent-ring resonators were placed above the MIM waveguide, Fano resonance with asymmetrical line shape appeared in the transmission spectrum due to the interference between the light⁻dark resonant modes. The sensitivity and figure of merit were as high as 880 nm/RIU and 964, respectively.

Reducing depressive or anxiety symptoms in post-stroke patients: Pilot trial of a constructive integrative psychosocial intervention.

Background: About 30% of stroke survivors clinically have depressive symptoms at some point following stroke and anxiety prevalence is around 20-25%.

Objective: The purpose of this brief report is to evaluate a pilot trial of a constructive integrative psychosocial intervention (CIPI) over standard care in post-stroke depression or anxiety.

Methods: Patients were randomly assigned to either CIPI ( = 23) or standard care ( = 19).