Publications by authors named "Yih Yih Kok"

Background: Resilience contributes to mental well-being, hence expediting recovery from stressful events. Health professions students, in particular, often experience heightened levels of stress and anxiety due to academic demands and other stressors. This study aimed to explore the factors contributing to resilience and identify support systems that universities can implement to help undergraduate health professions students build resilience and manage their mental well-being.

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  • * Marine algae contain a variety of bioactive compounds that possess properties such as anti-inflammation and antioxidant effects, making them appealing for pharmaceutical applications.
  • * This article explores how these algal compounds might protect against neurodegeneration in AD and their potential roles in both modifying the disease and managing symptoms.
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Algae and its metabolites have been a popular subject of research in numerous fields over the years. Various reviews have been written on algal bioactive components, but a specific focus on Antarctic-derived algae is seldom reviewed. Due to the extreme climate conditions of Antarctica, it is hypothesized that the acclimatized algae may have given rise to a new set of bioactive compounds as a result of adaptation.

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  • Cardiovascular diseases, particularly atherosclerosis, are major global health issues leading to high mortality rates from conditions like ischemic heart disease and stroke.
  • Current treatments for atherosclerosis are inadequate, raising the need for new and effective therapies.
  • Emerging approaches such as cell-based and nanoparticle-based therapies are explored in the paper, detailing their mechanisms, pros and cons, and recent advancements to combat atherosclerosis.
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Microalgae are well known for their metal sorption capacities, but their potential in the remediation of hydrophobic organic compounds has received little attention in polar regions. We evaluated in the laboratory the ability of an Antarctic microalga to remediate diesel hydrocarbons and also investigated physiological changes consequent upon diesel exposure. Using a polyphasic taxonomic approach, the microalgal isolate, WCY_AQ5_1, originally sampled from Greenwich Island (South Shetland Islands, maritime Antarctica) was identified as sp.

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  • Water pollution, particularly from toxic phenolic compounds, poses a significant threat to human and animal health, necessitating effective removal methods before wastewater is released into the environment.
  • Biotechnology is addressing this issue through biological treatment methods, especially using microorganisms and microalgae, which are cost-efficient in degrading organic pollutants like phenol.
  • This review highlights bibliometric trends from 2000-2020 in research on algae for bioremediation, noting an increase in publications, particularly from countries like China, Spain, and the U.S., while analyzing the mechanisms of phenol degradation by algae using software tools like VOSviewer and SciMAT.
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The achievement of learning goals via laboratory practical depends on both extrinsic and intrinsic factors. They could be limited by laboratory time, incurred cost, safety, self-efficacy, inadequate prior preparation by learners, and different learning styles. Hence, virtual laboratory simulation (vLAB) may be an appropriate e-learning tool to overcome these restrictions.

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Nutrition can modulate host immune responses as well as promote anticancer effects. In this study, two nutritional supplements, namely gamma-tocotrienol (γT3) and were evaluated for their immune-enhancing and anticancer effects in a syngeneic mouse model of breast cancer (BC). Five-week-old female BALB/c mice were fed , γT3, or a combination of and γT3 ( + γT3) for 56 days.

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Plastics have enormous impacts to every aspect of daily life including technology, medicine and treatments, and domestic appliances. Most of the used plastics are thrown away by consumers after a single use, which has become a huge environmental problem as they will end up in landfill, oceans and other waterways. These plastics are discarded in vast numbers each day, and the breaking down of the plastics from micro- to nano-sizes has led to worries about how toxic these plastics are to the environment and humans.

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  • Increasing concern exists about the toxic effects of microplastics and copper on microalgae, yet limited research has been done on their combined toxicity over long-term exposure.
  • The study focused on two freshwater microalgae, Chlorella sp. and Pseudokirchneriella subcapitata, and found that while microalgae were sensitive to copper, they tolerated microplastics; however, microplastics heightened copper toxicity during extended exposure.
  • The research revealed significant oxidative stress and structural changes in the microalgae, with most copper remaining in its free ionic form and low levels being absorbed by microplastics, highlighting potential environmental risks due to mixtures of these contaminants.
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Plastics, with their many useful physical and chemical properties, are widely used in various industries and activities of daily living. Yet, the insidious effects of plastics, particularly long-term effects on aquatic organisms, are not properly understood. Plastics have been shown to degrade to micro- and nanosize particles known as microplastics and nanoplastics, respectively.

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Fouling of marine surfaces has been a perpetual problem ever since the days of the early sailors. The tenacious attachment of seaweed and invertebrates to man-made surfaces, notably on ship hulls, has incurred undesirable economic losses. Graphene receives great attention in the materials world for its unique combination of physical and chemical properties.

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Girinimbine, a carbazole alkaloid isolated from the stem bark of Murraya koenigii was tested for the in vitro anti-tumour promoting and antioxidant activities. Anti-tumour promoting activity was determined by assaying the capability of this compound to inhibit the expression of early antigen of Epstein-Barr virus (EA-EBV) in Raji cells that was induced by the tumour promoter, phorbol 12-myristate 13-acetate. The concentration of this compound that gave an inhibition rate at fifty percent was 6.

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This study aimed to assess the inhibitory activities of methanol extracts from the microalgae Ankistrodesmus convolutus, Synechococcus elongatus, and Spirulina platensis against Epstein-Barr virus (EBV) in three Burkitt's lymphoma (BL) cell lines, namely Akata, B95-8, and P3HR-1. The antiviral activity was assessed by quantifying the cell-free EBV DNA using real-time polymerase chain reaction (PCR) technique. The methanol extracts from Ankistrodesmus convolutus and Synechococcus elongatus displayed low cytotoxicity and potent effect in reducing cell-free EBV DNA (EC(50)<0.

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