Publications by authors named "Yiguo Zhou"
In this study, we analyzed the dynamic molecular epidemiology of herpangina based on pharyngeal swabs and demographic data collected from children with herpangina monitored in Tongzhou district in China from January 2021 to December 2022. A total of 1022 herpangina cases were diagnosed. Out of 225 samples collected, 56.
View Article and Find Full Text PDFTo explore impact of the propensity to coronavirus disease 2019 (COVID-19) vaccine/vaccination on influenza vaccination from willingness to behavior after COVID-19 pandemic among older adults in rural China. A combined study involving a cross-sectional survey for the willingness of influenza vaccination, a health education momentary intervention and a community intervention program were conducted from September 11 to 16, 2023 among rural older adults in China. Totally 3138 individuals were investigated in this study with 1923 (61.
View Article and Find Full Text PDFArticle Synopsis
- Infectious diseases are a significant global threat, highlighting the need to enhance the capabilities of the public health workforce through the development of the Infectious Disease Control Competency Scale (IDCCS).
- The IDCCS was created by reviewing existing literature and involving expert feedback through a Delphi process, leading to the identification of key indicators within three main dimensions: knowledge, practical skills, and leadership.
- The final IDCCS includes a three-level scale with four primary dimensions and demonstrates strong reliability and validity, effectively serving as a framework for improving the competencies of public health professionals.
Background: Indoor residual spraying (IRS) has been implemented to prevent malaria in Zambia for several decades, but its effectiveness has not been evaluated long term and in Vubwi District yet. This study aimed to assess the association between IRS and the malaria burden in Zambia and Vubwi District and to explore the factors associated with refusing IRS.
Methods: A retrospective study was used to analyze the association between IRS and malaria incidence in Zambia in 2001-2020 and in Vubwi District in 2014-2020 by Spearman correlation analysis.
Article Synopsis
- The COVID-19 pandemic has significantly affected food security and nutrition globally, with lasting impacts particularly on school-age children, adolescents, and young adults.
- This review analyzed 42 published studies to evaluate the changes in dietary habits during the pandemic, finding that juice intake increased and alcohol consumption decreased overall.
- Age-specific findings revealed that school-age children increased their intake of fruits and dairy, adolescents consumed more vegetables and meals, while young adults saw reduced carbs and alcohol, but increased protein and dairy.
Objective: To describe the lipid metabolic profile of different patients with coronavirus disease 2019 (COVID-19) and contribute new evidence on the progression and severity prediction of COVID-19.
Methods: This case-control study was conducted in Peking University Third Hospital, China. The laboratory-confirmed COVID-19 patients aged ≥18 years old and diagnosed as pneumonia from December 2022 to January 2023 were included.
Purpose: To evaluate the impact of momentary intervention on the willingness and actual uptake of influenza vaccination among the elderly in China.
Methods: A cross-sectional study assessed the willingness of the elderly to receive influenza vaccination, and an momentary intervention aimed to increase vaccination willingness among those initially unwilling. The elderly reporting a willingness were offered free influenza vaccination through a community intervention program.
Objective: The study analyzed the impact of urbanization on epidemiological characteristics of respiratory infectious disease in Tongzhou District, Beijing during 2014-2022 to provide reference for prevention and control priorities of respiratory infectious diseases during the innovative urbanization process in China.
Methods: The incidence data of notifiable respiratory infectious diseases (NRIDs) in Tongzhou Beijing during 2014-2022 were summarized. The trend of incidence rate was analyzed by Joinpoint regression model, and entropy method was performed to construct the comprehensive index of urbanization (CIU) and generalized linear model was used to analyze the influence of CIU on the incidence rate of respiratory infectious diseases.
Background: The study evaluated the protective effect of 13-valent pneumococcal polysaccharide conjugate vaccine (PCV13) against all-cause hospitalized pneumonia in children in Beijing.
Methods: Based on the vaccination record and inpatient medical record database of Beijing, children born in 2017 in Beijing, matched by age, gender, and district of the children with the ratio of 1:4, were selected as the vaccinated and unvaccinated groups according whether if vaccinated with PCV13. The incidence rate and 95 % confidence interval (95 %CI), vaccine effectiveness (VE) and direct medical costs of all-cause hospitalized pneumonia were calculated and compared within the same period of 12 months, 18 months, 24 months and 30 months after the birth of the child.
Objectives: To explore epidemiological changes of Japanese encephalitis (JE) in a long-time span and evaluate the impact of mass immunisation.
Method: Data on JE cases from hospitals and the county Centers for Disease Control and Prevention in Guizhou Province was collected between 2005 and 2021. Epidemiological changes were analyzed according to a series of policy implementations and the coronavirus disease 2019 (COVID-19) pandemic.
Article Synopsis
- The study investigates how human adenovirus (HAdV) affects lipid metabolism in infected patients, focusing on those with pneumonia and upper respiratory tract infections (URTI).
- Researchers analyzed blood samples from 35 patients during acute and recovery stages, finding that most differential metabolites were lipids, particularly in the sphingolipid metabolism pathway.
- The results indicate that increased levels of ceramide and lactosylceramide in pneumonia patients suggest that targeting lipid metabolism could be a potential treatment strategy against HAdV infections.
Few studies focused on human papillomavirus (HPV) in male patients. This study aimed to explore the detection rate and genotyping of HPV among male patients in Beijing to provide a reference for formulating prevention strategies for HPV infection. The cross-sectional study was conducted in Beijing Chaoyang Hospital from November 2015 to March 2023.
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- - A study was conducted to understand the metabolic changes in urine of patients with severe fever with thrombocytopenia syndrome (SFTS) by comparing affected individuals to a healthy control group, ruling out other medical conditions.
- - The results highlighted that alterations in tryptophan and phenylalanine metabolism could differentiate between SFTS patients and healthy controls, with specific metabolites linked to the severity of the disease.
- - These findings suggest that targeting metabolic pathways related to tryptophan and phenylalanine could help in understanding SFTS better and developing potential treatments.
Background: The global COVID-19 pandemic presented an immense obstacle to public health, with vaccination emerging as a crucial measure to curb transmission. This study aimed to evaluate the willingness, hesitancy, and coverage of SARS-CoV-2 vaccines among healthcare workers (HCWs) in Tanzania and reveal their concerns about SARS-CoV-2 vaccines and the reasons that might prevent them from getting vaccinated.
Methods: We conducted a cross-sectional study using an anonymous online survey from October to November 2022.
Background: Men who have sex with men (MSM) have an increased risk of human papillomavirus (HPV) infection. This study aimed to assess the incidence, persistence, and clearance of anogenital HPV infections among MSM and the correlates in a 3-year community cohort study.
Methods: From 2015 to 2019, MSM were recruited and followed up at 6, 12, 24, and 36 months in Taiwan.
To analyze changes in the detection of parainfluenza virus (PIV) in children hospitalized with acute respiratory tract infection (ARTI) during 2014-2022 in Hubei Province, and explore the impact of the universal two-child policy and the public health measures against COVID-19 epidemic on the prevalence of PIV in China. The study was conducted at the Maternal and Child Health Hospital of Hubei Province. Children aged <18 years with ARTI admitted from January 2014 to June 2022 were enrolled.
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- Parents play a crucial role in vaccine decisions for children, so it's essential to understand their beliefs about the SARS-CoV-2 vaccine for ages 3-17.
- A survey conducted in seven provinces of China found that 20.30% of parents were hesitant about getting vaccinated themselves, while only 7.80% were hesitant about vaccinating their children, with concerns about disease severity and susceptibility influencing these attitudes.
- The study concludes that parents' perceptions of threat can create inconsistencies in their vaccination choices for themselves compared to their children, highlighting the need for better education and misinformation correction regarding COVID-19 to reduce vaccine hesitancy.
Vaccine hesitancy is a significant obstacle to the prevention and control of coronavirus disease 2019, especially among people with human immunodeficiency virus (HIV) in developing countries like Malawi, where HIV prevalence rate is high and limited data is available on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine hesitancy among people living with HIV (PLHIV). This study was conducted among people aged ≥18 years at Mpemba health center, Blantyre. All PLHIV were interviewed using a structured questionnaire.
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- - The study examines how the universal two-child policy in China affected the rates of Influenza virus (IFV) infections among hospitalized children with acute respiratory tract infections (ARTI) from 2014 to 2022.
- - Findings show that the IFV positive rate increased significantly after the policy's implementation, particularly among children under one year, reaching a peak in 2019, but dropped sharply during the initial COVID-19 outbreak.
- - The results highlight a shift in the epidemiological patterns of IFV infections and suggest the need for future research on the health impacts of public health measures regarding COVID-19 on IFV transmission.
Impact of influenza virus infection on lung microbiome in adults with severe pneumonia.
Ann Clin Microbiol Antimicrob
June 2023
Background: Bacterial and viral infections are commonly implicated in the development of pneumonia. We aimed to compare the diversity and composition of lung bacteria among severe pneumonia patients who were influenza virus positive (IFVP) and influenza virus negative (IFVN).
Methods: Bronchoalveolar lavage fluid specimens were procured from patients diagnosed with severe pneumonia to investigate the microbiome utilizing 16S-rDNA sequencing.
Article Synopsis
- - The study examined the dynamics of respiratory syncytial virus (RSV) among hospitalized children with acute respiratory tract infections in Hubei Province from 2014 to 2022, highlighting a lack of longitudinal data on the virus in the region.
- - Results indicated that RSV was detected in 11.1% of hospitalized children, with higher rates in infants under 1 year old, and those with lower respiratory tract infections, showing a pronounced seasonal pattern peaking between December and February.
- - The research also assessed the effects of China's 2-child policy and the COVID-19 pandemic on RSV prevalence, using statistical models to analyze changes in detection rates before and after these events.
Introduction: Men who have sex with men (MSM) are increasingly using geosocial networking (GSN) mobile applications (apps) to socialize in the community. Our study aimed to compare sexual behaviors between app-using MSM (app users) and non-app-using MSM (non-app users), and evaluate the association between app use and sexually transmitted infections (STIs).
Methods: Eligible MSM were recruited from January to August 2017 in three metropolitan cities: Guangzhou, Shenzhen and Wuxi.