Comparing the bowel cleansing efficacy between sodium picosulfate vs. 2L polyethylene glycol electrolyte lavage solution for colonoscopy: a prospective observational study.

Background: This study aimed to compare the bowel cleansing efficacy, adverse reactions, and patient compliance of two low-volume bowel preparation regimens, sodium picosulfate (PICO) and 2 L polyethylene glycol electrolyte lavage solution (2 L PEG-ELS).

Methods: This single-center, prospective observational trial was conducted at the Gastrointestinal Endoscopy Center of The Third People's Hospital of Chengdu between May and October 2023. Patients undergoing colonoscopy were enrolled, with the primary outcome being the rate of adequate bowel cleansing, as assessed by the Boston Bowel Preparation Scale (BBPS) with three segments scoring ≥ 2.

Cost Utility Analysis of Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder: Randomized Controlled Trial.

Background: Unguided internet-based cognitive behavioral therapy (ICBT) has been proven effective for major depressive disorder (MDD). However, few studies have examined its cost-effectiveness in low-resource countries and under nonspecialist routine care.

Objective: This study aimed to evaluate the short- and long-term cost utility of unguided ICBT compared to a waitlist control for persons with MDD from the perspectives of society and the health care system.

Prevalence of myopia and refractive parameters among children and adolescents in Hi-tech District of Chengdu City.

Objective: To analyze the prevalence of myopia among children and adolescents in Chengdu from 2021 to 2023, providing insights for myopia prevention and control.

Methods: This study was a school-based cross-sectional study in children and adolescents aged 3-18 years in Hi-tech District of Chengdu City. All the students underwent comprehensive ocular measurement, including uncorrected binocular visual acuity (VA), spherical equivalent error (SER) with noncycloplegic autorefraction, corneal radius (CR), and axial length (AL).

Stabilizing Layered Oxide Cathodes Based on Universal Surface Residual Alkali Conversion Chemistry for Rechargeable Secondary Batteries.

Layered transition metal oxides (LTMOs) are attractive cathode candidates for rechargeable secondary batteries because of their high theoretical capacity. Unfortunately, LTMOs suffer from severe capacity attenuation, voltage decay, and sluggish kinetics, resulting from irreversible lattice oxygen evolution and unstable cathode-electrolyte interface. Besides, LTMOs accumulate surface residual alkali species, like hydroxides and carbonates, during synthesis, limiting their practical application.

Impact of Laser-Assisted Hatching on Cognitive and Metabolic Development of Singletons Conceived Through Frozen-Thawed Embryo Transfer: A Matched Cohort Study.

Objective: This study aimed to examine the impact of laser-assisted hatching (LAH) on the physical, metabolic, cognitive and behavioural profiles of singletons conceived through frozen-thawed embryo transfer (FET) at the preschool age.

Design: A matched cohort study.

Setting: The reproductive centre of Women's Hospital, Zhejiang University School of Medicine.

Liver-Secreted Extracellular Vesicles Promote Cirrhosis-Associated Skeletal Muscle Injury Through mtDNA-cGAS/STING Axis.

Skeletal muscle atrophy (sarcopenia) is a serious complication of liver cirrhosis, and chronic muscle inflammation plays a pivotal role in its pathologenesis. However, the detailed mechanism through which injured liver tissues mediate skeletal muscle inflammatory injury remains elusive. Here, it is reported that injured hepatocytes might secrete mtDNA-enriched extracellular vesicles (EVs) to trigger skeletal muscle inflammation by activating the cGAS-STING pathway.

The phonation test can distinguish the patient with Parkinson's disease via Bayes inference.

Unlabelled: Parkinson's disease (PD) is a neurodegenerative disease with various clinical manifestations caused by multiple risk factors. However, the effect of different factors and relationships between different features related to PD and the extent of those factors leading to the incidence of PD remains unclear. we employed Bayesian network to construct a prediction model.

Probabilistic Attention Map: A Probabilistic Attention Mechanism for Convolutional Neural Networks.

The attention mechanism is essential to (CNN) vision backbones used for sensing and imaging systems. Conventional attention modules are designed heuristically, relying heavily on empirical tuning. To tackle the challenge of designing attention mechanisms, this paper proposes a novel probabilistic attention mechanism.

Intra-arterial Alteplase Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulation (IAT-TOP): Study protocol and rationale.

Rationale: The Chemical Optimization of Cerebral Embolectomy (CHOICE) trial suggested that the administration of intra-arterial alteplase after successful endovascular thrombectomy (EVT) may improve neurological outcomes in patients with acute ischemic stroke due to large-vessel occlusion (AIS-LVO) in the anterior circulation. However, the use of adjunctive intra-arterial alteplase following successful EVT in acute posterior circulation stroke remains unexplored.

Aims: This study aims to investigate the efficacy and safety of intra-arterial alteplase after successful EVT for AIS-LVO in the posterior circulation.

High-performance 2D electronic devices enabled by strong and tough two-dimensional polymer with ultra-low dielectric constant.

As the feature size of microelectronic circuits is scaling down to nanometer order, the increasing interconnect crosstalk, resistance-capacitance (RC) delay and power consumption can limit the chip performance and reliability. To address these challenges, new low-k dielectric (k < 2) materials need to be developed to replace current silicon dioxide (k = 3.9) or SiCOH, etc.

Zeolite Encapsulation to Enhance Interfacial Gas Availability for Photocatalytic Hydrogen Peroxide Production.

The photocatalytic oxidation of water with gaseous oxygen is environmentally benign for the synthesis of hydrogen peroxide (HO), but it is currently constrained by the inadequate supply of gaseous oxygen at the catalyst surface in a solid-liquid-gas triple-phase reaction system. Herein, we address this challenge by employing the zeolite encapsulated catalysts that efficiently enrich gaseous oxygen and accelerate the HO synthesis in aqueous conditions. We focus on the classical titania photocatalyst, encapsulating it within siliceous MFI zeolite crystals.

"Sadness smile" curve: Processing emotional information from social network for evaluating thermal comfort perception.

Thermal comfort is a subjective perception, hence conventional evaluation using meteorological factors faces a technical challenge in precise assessment. Human beings have the nature to differentiate expressions of facial emotions when varied thermal environments are perceived. Facial expression scores can be taken as a predictor of perceived thermal comfort which can be precisely assessed using deep learning against physical factors.

Associations of childhood trauma with remission and treatment response after 12 weeks of selective serotonin reuptake inhibitor treatment in patients with major depressive disorder.

Objective: To explore the associations of childhood trauma and its subtypes with remission and treatment response after 12 weeks of selective serotonin reuptake inhibitor (SSRI) treatment among patients with major depressive disorder (MDD).

Methods: Data were from patients with MDD in the Depression Cohort in China. At baseline, the Childhood Trauma Questionnaire-Short Form was used to assess childhood trauma, including physical abuse, emotional abuse, sexual abuse, physical neglect, and emotional neglect.

IRIS, a randomised, double-blind, placebo-controlled trial of interleukin-6 receptor inhibition undergoing endovascular treatment in acute anterior circulation ischaemic stroke: study rationale and design.

Rationale: Neuroprotective strategies based on reperfusion therapy hold substantial promise for acute ischaemic stroke (AIS). Preclinical research indicates that tocilizumab, an interleukin-6 receptor antagonist, can attenuate ischaemia-reperfusion damage by exerting anti-inflammatory and neuroprotective effects.

Aim: To determine tocilizumab's efficacy and safety when combined with endovascular thrombectomy (EVT) in patients with acute anterior circulation large vessel occlusion (LVO).

Cation migration in layered oxide cathodes for sodium-ion batteries: fundamental failure mechanisms and practical modulation strategies.

Sodium-ion batteries (SIBs) are regarded as competitive candidates for the next generation of electrochemical energy storage (EES) systems due to their low cost and abundant sodium resources. Layered oxide cathodes have attracted much interest owing to their simple preparation process, high specific capacity and environmental friendliness. However, undesired cation migration during electrochemical reactions can lead to irreversible phase transitions and structural degradation of layered oxide cathode materials, resulting in a sharp decrease in specific capacity and energy density.

A Universal Interfacial Reconstruction Strategy Based on Converting Residual Alkali for Sodium Layered Oxide Cathodes: Marvelous Air Stability, Reversible Anion Redox, and Practical Full Cell.

Mn-based layered oxide cathodes have attracted widespread attention due to high capacity and low cost, however, poor air stability, irreversible phase transitions, and slow kinetics inhibit their practical application. Here, we propose a universal interfacial reconstruction strategy based on converting residual alkali to tunnel phase NaMnO for addressing the above mentioned issue simultaneously, using O3 NaNiFeMnO@2 mol % NaMnO (NaNFM@NMO) as the prototype material. The optimized material exhibits an initial capacity and energy density comparable with lithium-ion batteries.

Development of an Angular Stiffness Sensor to Measure Dental Implant Stability In Vitro.

This investigation aims to develop an angular stiffness sensor intended for measuring dental implant stability in bone. The sensor hardware included a tiny eccentric motor and an accelerometer to measure a flex constant of an implant with its abutment. The sensor software included a mechanics-based model to convert the flex constant to angular stiffness at the implant/abutment junction to indicate the stability.

Investigation of an improved ceramic-based pulse-forming line based on impedance matching electrode.

A ceramic-based pulse-forming line (PFL) is a solid-state device with a wide range of applications in compact pulsed power systems. In this paper, the characteristic impedance of a ceramic-based PFL is theoretically analyzed, and an improved PFL based on an impedance matching electrode is proposed. The improved PFL effectively increases the flat-top ratio and reduces the rise and fall times, enhancing its potential applicability.

Fe-Doped NiS Induces Self-Reconstruction for Urea-Assisted Water Electrolysis Enhancement.

Urea oxidation reaction (UOR) is an attractive alternative anodic reaction to oxygen evolution reaction (OER) for its low thermodynamic potential (0.37 V vs RHE). A major challenge that prohibits its practical application is the six-electron transfer process during UOR, demanding enhancements in the catalytic activity.

Identification of cigarettes with different grades by using FTIR microspectroscopy.

In this paper, FTIR microspectroscopy was used to identify the cigarettes of three different grades such as Jinwan cigarettes (J group), Yinxiangyipin cigarettes (Y group) and Hongsanhuan cigarettes (H group). IR spectra and peak-area ratios (A /A, A /A, A/A and A/A) revealed significant differences among H, Y and J groups, reflecting the changes in chemical compositions with increased grade. Discriminant analysis was carried out on basis of the above peak-area ratios, achieving 100% accuracy for identification of H, Y and J groups.