Publications by authors named "Yifen Zhuo"
Purpose: While esketamine shows promise as an adjunct in procedural sedation, its impact on postoperative cognitive recovery remains incompletely characterized. This study investigated the effects of esketamine on multiple dimensions of recovery, particularly cognition, in patients undergoing colonoscopy with propofol-based sedation.
Patients And Methods: We conducted this randomized, double-blinded, placebo-controlled trial from January 6, 2023, to May 20, 2024, at two hospitals in China.
Purpose: Intrathecal morphine is increasingly used for pain management in laparoscopic colorectal surgery. While ropivacaine shows advantages of reduced cardiotoxicity and faster motor recovery compared to bupivacaine, the impact of intrathecal morphine-ropivacaine combination on postoperative recovery quality remains unclear. This study aimed to evaluate this combination's effect on recovery outcomes after laparoscopic colorectal surgery.
View Article and Find Full Text PDFBackground: Remimazolam, a novel ultra-short-acting benzodiazepine, shows promise for procedural sedation. This study compared the cognitive recovery of remimazolam versus propofol in elderly patients undergoing colonoscopy.
Patients And Methods: In this prospective, randomized, double-blind, controlled trial, 228 patients aged ≥ 65 years undergoing outpatient colonoscopies were recruited.
Article Synopsis
- A study examined the effectiveness of a combined intranasal premedication of dexmedetomidine and esketamine in reducing emergence delirium and postoperative negative behavioral changes in young children undergoing tonsillectomy/adenoidectomy compared to each drug alone.
- The results showed that the combination significantly lowered the incidence of emergence delirium compared to esketamine alone, with a reduction from 38.1% to 9.4%, and also reduced postoperative negative behavioral changes compared to dexmedetomidine.
- Overall, the combined premedication led to better sedation, easier separation from parents, improved acceptance of anesthetic masks, shorter recovery times, and higher parental satisfaction compared to using either drug by itself.
Introduction: Many clinical trials have demonstrated the benefits of intraoperative systemic lidocaine administration in major abdominal surgeries. We tested the hypothesis that systemic lidocaine is associated with an enhanced early quality of recovery in patients following laparoscopic colorectal resection.
Patients And Methods: We randomly allocated 126 patients scheduled for laparoscopic colorectal surgery in a 1:1 ratio to receive either lidocaine (1.