Publications by authors named "Yifei Xu"

Background: Patients with chronic obstructive pulmonary disease (COPD) are at high risk of developing frailty and need to be prevented and managed. This study aims to investigate the relationship between dietary magnesium (Mg) intake and the risk of frailty in patients with COPD.

Methods: We conducted a cross-sectional study from the National Health and Nutrition Examination Survey (NHANES) in the United States, focusing on patients with COPD.

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During tunnel construction, the protracted mucking phase poses significant occupational health risks, particularly from dust exposure. This study delves into comprehensive numerical simulations to examine the spatiotemporal dynamics of dust particles during the mucking process. A distinct 'bimodal pattern' was characterized by higher concentrations in the mucking area (0-30 m) and the inverted arch area (60-110 m), where concentrations exceed 30 mg/m3 under all conditions.

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Background: COVID-19 is a respiratory disease, and its symptoms may be affected by the upper airways of adolescents.

Objective: To investigate the effect of parameters of adolescents' upper airways on COVID-19 symptom severity.

Methods: This retrospective study was performed from January to March 2022 at the Hospital of Stomatology, Xi'an Jiaotong University, Xi'an, China.

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Article Synopsis
  • Heart transplant patients with donor-specific antibodies (DSAs) face a higher risk of rejection, but some do not show antibody-mediated rejection despite having graft dysfunction.
  • A study involved 216 participants undergoing serial evaluations like endomyocardial biopsy (EMB) and echocardiograms to understand the relationship between DSAs, rejection types, and long-term outcomes.
  • Results indicated that both antibody-mediated rejection (pAMR+) and DSA-related left ventricle dysfunction significantly correlated with increased mortality and prolonged heart dysfunction, particularly if they occurred within the first six months after transplant.
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Background: The assessment of growth stages, typically determined by Cervical Vertebrae Maturation (CVM), plays a crucial role in orthodontics. However, there is a potential deviation from actual growth stages when using CVM. This study aimed to introduce CDSNet, an interpretable deep learning model for assessing growth stages based on cervical vertebrae, dentition, and frontal sinus in lateral cephalograms.

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Unravelling the influence of strain and geometric effects on the electrochemical reduction of carbon dioxide (CORR) on Cu-based (or Pd-based) alloys remains challenging due to complex local microenvironment variables. Herein, we employ two PdCu alloys (nanoparticles and nanodendrites) to demonstrate how CORR selectivity can shift from CO to HCOO. Despite sharing consistent phases, exposed crystal facets, and overall oxidative states, these alloys exhibit different local strain profiles due to their distinct geometries.

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Article Synopsis
  • The electrocatalytic reduction of CO to CO is made more efficient by a new mechanism that involves the transfer of hydrogen radicals, helping to speed up the hydrogenation step which leads to the formation of *COOH.
  • Researchers used nickel (Ni) paired with other metals (denoted as M) to enhance the conversion of CO by generating adsorbed hydrogen (H•), which in turn reduces CO to carboxyl radicals.
  • The choice of metal for pairing with Ni affects the strength of hydrogen adsorption, optimizing H• formation and resulting in a significant increase in CO reduction rates, achieving an impressive faradaic efficiency of up to 100% in certain solutions.
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Objective: This study investigated how obesity, BMI ≥ 30 kg/m, abdominal adiposity, and systemic inflammation relate to neuroinflammation using diffusion basis spectrum imaging.

Methods: We analyzed data from 98 cognitively normal midlife participants (mean age: 49.4 [SD 6.

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  • Fusarium head blight (FHB) is a serious problem for wheat production worldwide, as it causes yield losses and harmful mycotoxin contamination; this study investigates FHB trends and meteorological risk factors across regions in Jiangsu Province, China, from 1965 to 2023.
  • The analysis found that Regions I and III consistently had higher FHB rates, with Region III experiencing a significant increase in severity since 2000, surpassing Region I post-2010.
  • The study highlighted a stronger correlation between specific meteorological conditions during the grain filling stage and FHB incidence, suggesting that increased humidity and temperature post-2000 may have created favorable conditions for FHB development.
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HoF crystals of varying sizes and morphologies were synthesized by controlling the amount of water. As the water content gradually decreased, the size of the crystals reduced, transforming from microcrystals to approximately 100 nm nanocrystals with unique morphologies. At room temperature, the pressure-induced phase transitions, and photoluminescence (PL) properties of HoF micro/nanocrystals are studied using in situ high-pressure PL technique.

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By engaging in redox processes, ferroptosis plays a crucial role in sepsis-induced acute lung injury (ALI). Although iron stimulates calcium signaling through the stimulation of redox-sensitive calcium pathways, the function of calcium signals in the physiological process of ferroptosis in septic ALI remains unidentified. Iron homeostasis disequilibrium in ferroptosis is frequently accompanied by aberrant calcium signaling.

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Article Synopsis
  • Atherosclerosis is an inflammatory heart disease, and the study explores how immune cells, specifically C1q+ macrophages and CD8T cells, influence its progression.
  • Researchers used various techniques, including single-cell RNA sequencing and mouse models, to examine how these immune cells interact.
  • The findings suggest that C1q+ macrophages help promote atherosclerosis by preventing CD8T cell death and enhancing their activation through a specific pathway (C1q-C1qbp axis).
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Unlabelled: Amauroderma (Blume and T. Nees) Torrend (Ganodermataceae) ( ) has been found to have anti-inflammatory ability in previous studies. The present study aimed to verify the therapeutic benefits of in the treatment of ulcerative colitis and to investigate its underlying mechanism of action.

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Background: Combined art activities can improve the neural network function within various brain regions involved in emotions, cognition, and behavior, thereby preventing or reversing cognitive decline. However, few studies have systematically examined its effects. Furthermore, the impact of nurse-led art-based cognitive intervention on cognitive and psychological health is unclear.

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A multimodal exercise training program might be the best way to improve motor and cognitive function in patients with Parkinson's disease (PD), but this has yet to be fully proven in PD patients with mild cognitive impairment (MCI). This study aims to examine the feasibility and effectiveness of a theory-based, multi-component exercise intervention in older people with PD-MCI. Participants were randomized into an intervention group (n=23) and an active control group (n=23), receiving the theory-based multi-component exercise intervention and Parkinson's health exercises, respectively.

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Post-stroke depression (POSD) is a common difficulty and most predominant emotional syndrome after stroke often consequences in poor outcomes. In the present investigation, we have designed and studied the neurologically active celastrol/minocycline encapsulated with macrophages-derived exosomes functionalized PLGA nanoformulations (CMC-EXPL) to achieve enhanced anti-inflammatory behaviour and anti-depressant like activity in a Rat model of POSD. The animal model of POSD was established through stimulating process with chronic unpredictable mild stress (CUM) stimulations after procedure of middle cerebral artery occlusion (MCAO).

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HONO is a critical precursor of •OH, but its sources are controversial due to its complex formation mechanism. This study conducted comprehensive observations in Zhengzhou from April 26 to May 11, 2022. Low NO concentrations were observed during the Covid epidemic period (EP) (10.

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Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by ciliary structural abnormalities and dysfunction, leading to chronic rhinosinusitis, otitis media with effusion, bronchiectasis, and infertility. Approximately half of Japanese PCD cases are attributed to variants in the dynein regulatory complex subunit 1 (DRC1) gene, predominantly featuring homogeneous deletions of exons 1-4 spanning 27,748 base pairs on chromosome 2. Here, we report 10 new PCD cases (9 families) in addition to 29 previously reported cases (24 families) caused by DRC1 variants.

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We previously demonstrated that glycyrrhizin (GL) suppressed inflammation and carcinogenesis in an azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced murine model of colorectal cancer (CC). In this study, we found an accumulation of regulatory T cells (Tregs) in the spleen and suppression by GL in model mice. ICR mice were divided into four groups: Control, GL, CC, and GL-treated CC (CC+GL), and were sacrificed 20 weeks after AOM/DSS treatment.

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Over the past decade, advancements in high-throughput sequencing technologies have led to a qualitative leap in our understanding of the role of the microbiota in human diseases, particularly in oncology. Despite the low biomass of the intratumoral microbiota, it remains a crucial component of the tumor immune microenvironment, displaying significant heterogeneity across different tumor tissues and individual patients. Although immunotherapy has emerged a major strategy for treating tumors, patient responses to these treatments vary widely.

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Due to the general incompleteness of photochemical reactions, the photostationary structure in traditional photo-controlled host-guest self-assembly transfer is usually disordered or irregular. This fact readily affects the photoregulation or improvement of related material properties. Herein, a photoexcitation-induced aggregation molecule, hydroxyl hexa(thioaryl)benzene (HB), was grafted into β-cyclodextrin to form a host-guest system.

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